Asymmetric synthesis with chiral hydrogenolysable amines : A new route to enantiomerically pure amino diols

Heterocycles

Volumn 45, Issue 8, 1997, Pages 1451-1455

  Segat, Fabienne ^a   Lingibé, Olivier ^a   Graffe, Bernadette ^a   Sacquet, Marie Claude ^a   Lhommet, Gérard ^a  

^a SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0342800200     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-97-7849     Document Type: Article

References (14)

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7. P. Gmeiner and A. Kärtner, Synthesis, 1995, 83 and references therein.
8. O.M. Friedman and E. Boger, J. Am. Chem. Soc., 1956, 78, 4659.
9. O. Lingibé, B. Graffe, M.-C. Sacquet, and G. Lhommet, Heterocycles, 1995, 41, 1931 and references cited therein.
10. V. Caplar, A. Lisini, F. Kajfez, D. Kolbah, and V. Sunjic, J. Org. Chem., 1978, 43, 1355.
11. Unreacted amino acid (8) and side-product (9) were isolated from the mixture of the crude products. Compound 9 may arise from the acido-basic equilibrium followed by anionic condensation : (Figure Presented)
12. J.P. Célérier, E. Deloisy-Marchalant, and G. Lhommet, J. Heterocycl. Chem., 1984, 21, 1633.
13. 2 (1 atm or 180 atm).
14. 20of 7a and 7b are identical to those of amino alcohols obtained by reduction of L-aspartic and L-glutamic acids.