Ascorbic Acid Stabilization of Re-188- And I-131-Radiolabeled Peptides for Radiotherapy

Radiochimica Acta

Volumn 79, Issue 2, 1997, Pages 93-97

  Guhlke, S ^a   Zamora, P O ^a,b   Sartor, J ^a   Knapp Jr , F F ^c   Bender, H ^a   Rhodes, B A ^b   Biersack, H J ^a  

^a UNIVERSITY OF BONN   (Germany)

^b RhoMed Inc   (United States)

^c OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

Peptides; Radiolysis; RC 160; Rhenium 188; Small cell lung carcinoma

Indexed keywords

EID: 0342788336     PISSN: 00338230     EISSN: None     Source Type: Journal    
DOI: 10.1524/ract.1997.79.2.93     Document Type: Article

References (17)

1. 123I-Tyr3]-octreotide; the Rotterdam experience with more than 1000 patients. Europ. J. Nucl. Med. 20, 716-731 (1993).
2. Stolz, B., Smith-Jones, P., Albert, R., Tolcsvai, L., Briner, U., Ruser, G., Maecke, H., Weckbecker, G., Bruns, C.: Somatostatin analogues for somatostatin-receptor-mediated radiotherapy of cancer. Digestion 57 (Suppl. 1), 17-21 (1996).
3. De Jong, M., Bakker, W. H., Krenning, E. P., Breeman, W. A. P., van der Pluijm, M. E., Bernard, B. F., Visser, T. J., Jermann, E., Behe, M., Powell, P., Maecke, H. R.: Yttrium-90 and indium-111 labelling, recleptor binding and biodistribution of [DotaO, D-Phe1, Tyr3]octreotide, a promising somatostatin analogue for radionuclide therapy. Europ. J. Nucl. Med. 24, 368-371 (1997).
4. Schally, A. V.: Hypothalmic hormones: from neuroendocrinology to cancer therapy. Anticancer Drugs 5, 115-130 (1994).
5. 188Re.RC160, a directly-radiolabeled somatostatin analog. Int. J. Cancer 65, 214-220 (1996).
6. 188Re-RC-160, a somatostatin analogue. Tumor Targeting 2, 49-59 (1996).
7. Knapp, F. F. Jr., Mirzahdeh, S., Beets, A. L., Sharkey, R., Griffiths, G., Juweid, M., Goldenberg, D. M.: Curie-scale tungsten-188/rhenium generators for routine clinical applications, in (M. Nicolini, B. Bandoli, U. Mazzi, eds.) Technetium Chemistry and Nuclear Medicine 4, Padova, SGEditoriali (1995) pp. 319-324.
8. Zamora, P. O., Marek, M., Knapp, F. F., Jr.: Preparation of Re-188-RC-160 somatostatin analog: a peptide for radiotherapy. Appl. Rad. Isotopes 48, 305-309 (1997).
9. Djura, P., Hoskinson, R. M.: 125-I-somatostatin analogues: high performance liquid chromatography profiles and antibody binding properties following three methods of radioiodination. J. Chrom. 389, 261-266 (1987).
10. McLemore, T. L., Eggleston, J. C., Shoemaker, R. H., Abbott, B. J., Bohlman, M. E., Liu, C., Fine, D. L., Mayo, J. G., Boyd, M. R.: Comparison of intrapulmonary, percutaneous intrathoracic, and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice. Cancer Res. 48, 2880-2886 (1988).
11. Zamora, P. O., Domalewski, M., Marek, M. J., Budd, P., Rhodes, B. A.: Quantitation of radiolabeled antibody binding to cells by thin-layer chromatography. Nucl. Med. Biol. 21, 205-210 (1994).
12. Bakker, W. H., Breeman, W. A. P., van der Pluijm, M. E., de Jong, M., Visser, T. J., Krenning, E. P.: Iodine-131 labelled octreotide : not an option for somatostatin receptor therapy. Eur. J. Nucl. Med. 23, 775-181 (1996).
13. Chakrabarti, M. C., Le, N., Paik, C. H., De Graff, W. G., Carrasquillo, J. A.: Prevention of radiolysis of monoclonal antibody during labeling. J. Nucl. Med. 37, 1384-1388 (1996).
14. Hsieh, B.-T., Callahan, A. P., Beets, A. L., Ting, G., Knapp, F. F., Jr.: Ascorbic acid saline eluant increases Re-188 yields after "wet" storagae of W-188/Re-188 generators. Appl. Radiat. Isot. 47, 23-26 (1996).
15. Krenning, E. P., Kooji, P. P. M., Bakker, W. H. B., Breeman, W. A. P., Postema, P. T. E., Kwekkeboom, D. J., Oei, H. Y., de Jong, M., Visser, T. J., Regs, A. E. M., Lamberts, S. W. J.: Radiotherapy with a radiolabeled somatostatin analogue, [111In-DTPA-d-Phe1]octreotide: a case history. Ann. N.Y. Acad. Sci. 733, 496-506 (1994).
16. de Jong, M., Breeman, W. A. P., Bernard, B. F., Rolleman, E. J., Hofland, L. J., Visser, T. J., Setyono-Han, B., Bakker, W. H., Van der Pluijm, M. E., Krenning, E. P.: Evaluation in vitro and in rats of 161Tb-DTPA-octreotide, a somatostatin analogue with potential for intraoperative scanning and radiotherapy. Europ. J. Nucl. Med. 22, 608-616 (1995).
17. Hosono, M., Hosono, M. N., Haberberger, T., Zamora, P. O., Guhlke, S., Bender, H., Knapp, F. F., Jr., Biersack, H.-J.: Localization of small-cell lung cancer xenografts with I-125, In-111, and Re-188 octreotides. Jpn. J. Nucl. Med. 87, 995-1000 (1996).