Lipase-catalyzed enantioselective alcoholysis of enol acetates: Optical resolution of ketones and aldehydes using lipases in organic solvents

Enantiomer

Volumn 1, Issue 3, 1996, Pages 219-222

  Naemura, Koichiro ^a   Kittaka, Koji ^a   Murata, Masaki ^a   Ida, Hirotsugu ^a   Hirose, Keiji ^a   Tobe, Yoshito ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Enantioselective Reaction; Enol Acetate; Lipase Catalyzed Alcoholysis; Optical Resolution of Aldehyde; Optical Resolution of Ketone; Stereomodel

Indexed keywords

EID: 0342737570     PISSN: 10242430     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. M. P. Schneider, Enzymes as Catalysts in Organic Synthesis, Reidel, Dordrecht, 1986;
2. D. H. G. Crout and M. Chrisen In Modern Synthetic Methods, ed. R. Scheffold, Springer-Verlag, Berlin, 1989, vol. 5, pp. 1-14;
3. H. G. Daviers, R. H. Green, D. R. Kelly and S. M. Roberts, Biotransformations in Preparative Organic Chemistry, Academic Press, London, 1990.
4. E. Santaniello, P. Ferraboschi, P. Grisenti and A. Manzocchi, Chem. Rev., 1992, 92, 1071 and references cited therein.
5. K. Matsumoto, S. Tsutsumi, T. Ihori, and H. Ohta, J. Am. Chem. Soc., 1990, 112, 9614.
6. H. O. House, W. L. Respess, and G. M. Whitesides, J. Org. Chem., 1966, 31, 3128.
7. H. O. House and W. F. Fischer, Jr., J. Org. Chem., 1969, 34, 3615;
8. P. Z. Bedoukian, Organic Syntheses, Wiley, New York, 1955, Collect Vol. 3, p. 127.
9. 3 requires M, 194.0939.
10. Lipase YS, lipase PS and lipase AY were supplied by the Amano Pharmaceutical Co. All lipases were used without further purification.
11. -1.