Intracerebroventricular injection of somatostatin sst5 receptor agonist inhibits gastric acid secretion in rats

European Journal of Pharmacology

Volumn 296, Issue 2, 1996, Pages 153-160

  Martínez, Vicente ^a,c   Coy, David H ^b   Lloyd, K C Kent ^a   Taché, Yvette ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Brain; Gastric acid secretion; Rat; SMS 201 995; Somatostatin analog; Somatostatin receptor subtype; Somatostatin sst2 receptor; Somatostatin sst3 receptor; Somatostatin sst5 receptor

Indexed keywords

DC 3287; DEXTRO PHENYLALANYLPHENYLALANYLPHENYLALANYL DEXTRO TRYPTOPHYLLYSYLTHREONYLPHENYLALANYLTHREONINAMIDE; DEXTRO PHENYLALANYLPHENYLALANYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLPHENYLALANYL DEXTRO [3 (2 NAPHTHYL)ALANINAMIDE]; OCTREOTIDE; RECEPTOR SUBTYPE; SOMATOSTATIN; SOMATOSTATIN 14; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR; SOMATOSTATIN RECEPTOR AGONIST; SOMATOSTATIN SST2 RECEPTOR; SOMATOSTATIN SST2 RECEPTOR AGONIST; SOMATOSTATIN SST3 RECEPTOR; SOMATOSTATIN SST3 RECEPTOR AGONIST; SOMATOSTATIN SST5 RECEPTOR; SOMATOSTATIN SST5 RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; CONTROLLED STUDY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH ACID SECRETION;

EID: 0342716477     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00690-7     Document Type: Article

References (35)

1. Bell, G.I. and T. Reisine, 1993, Molecular biology of somatostatin receptors, Trends Neurosci. 16, 34.
2. Breder, C.D., Y. Yamada, K. Yasuda, S. Seino, C.B. Saper and G.I. Bell, 1992, Differential expression of somatostatin receptor subtypes in brain, J. Neurosci. 12, 3920.
3. Bruno, J.F., Y. Xu, J. Song and M. Berelowitz, 1992, Molecular cloning and functional expression of a brain-specific somatostatin receptor, Proc. Natl. Acad. Sci. USA 89, 11151.
4. Bruno, J.F., Y. Xu, J. Song and M. Berelowitz, 1993, Tissue distribution of somatostatin receptor subtype messenger ribonucleic acid in the rat, Endocrinology 133, 2561.
5. Buscail, L., J.-P. Estève, N. Saint-Laurent, V. Bertrand, T. Reisine, A.-M. O'Carroll, G.I. Bell, A.V. Schally, N. Vaysse and C. Susini, 1995, Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms, Proc. Natl. Acad. Sci. USA, 92, 1580.
6. Feldberg, W.S., 1982, Fifty years on: Looking Back on Some Developments in Neurohumoral Physiology (Liverpool University Press, Liverpool) p. 31.
7. Finley, J.C.W., J.L. Maderdrut, L.J. Roger and P. Petrusz, 1981, The immunocytochemical localization of somatostatin-containing neurons in the central nervous system, Neuroscience 6, 2173.
8. Gu, Z.-F., V.D. Corleto, S.A. Mantey, D.H. Coy, P.N. Naton, and R.T. Jensen, 1995, Somatostatin receptor subtype 3 mediates the inhibitory action of somatostatin on gastric smooth muscle cells, Am. J. Physiol. 268, G739.
9. Hermann, G.E. and R.C. Rogers, 1989, Extrinsic neural control of brainstem gastric vago-vagal reflex circuits, in: Nerves and the gastrointestinal tract - Falk Symposium No. 50, eds. M.V. Singer and H. Goebell (MTP Press Ltd., Lancaster) p. 345.
10. Hisano, S. and S. Daikoku, 1991, Existence of mutual synaptic relations between corticotropin-releasing factor-containing and somatostatin-containing neurons in the rat hypothalamus, Brain Res. 545, 265.
11. Hoyer, D., G.I. Bell, M. Berelowitz, J. Epelbaum, W. Feniuk, P.P.A. Humphrey, A.-M. O'Carroll, Y.C. Patel, A. Schonbrunn, J.E. Taylor, and T. Reisine, 1995, Classification and nomenclature of somatostatin receptors, Trends Pharmacol. Sci. 16, 86.
12. Kong, H., A.M. DePaoli, C.D. Breder, K. Yasuda, G.I. Bell and T. Reisine, 1994, Differential expression of messenger RNAs for somatostatin receptor subtypes SSTR1, SSTR2 and SSTR3 in adult rat brain: analysis by RNA blotting and in situ hybridization histochemistry, Neuroscience 59, 175.
13. Lenz, J.H., I. Forquignon, G. Druge and H. Greten, 1989, Effects of neuropeptides on gastric acid and duodenal bicarbonate secretions in freely moving rats, Reg. Pept. 24, 293.
14. Lloyd, K.C.K., J. Wang, K. Aurang, P. Grönhed, D.H. Coy and J.H. Walsh, 1995, Activation of somatostatin receptor subtype 2 inhibits acid secretion in rats, Am. J. Physiol. 268, G102.
15. Martínez, V., D.H. Coy and Y. Taché, 1995, Influence of intracisternal injection of somatostatin analog receptor subtypes 2, 3 and 5 on gastric acid secretion in conscious rats, Neurosci. Lett. 186, 79.
16. O'Carroll, A.M., S.J. Lolait, M. Konig and L.C. Mahan, 1992, Molecular cloning and expression of a pituitary somatostatin receptor with preferential affinity for somatostatin-28, Mol. Pharmacol. 42, 939.
17. Osumi, Y., T. Ishikawa and M. Fujiwara, 1979, Effect of intraventricularly applied somatostatin on gastric acid secretion and mucosal blood flow in rats, in: Integrative Control Functions of the Brain, Vol. II, eds. M. Ito, K. Kubota, N. Tsukahara and K. Yagi (Elsevier/North Holland Biomedical Press, Kodansha Ltd., Tokyo) p. 261.
18. Pappas, T., Y. Taché and H. Debas, 1985, Cerebro-ventricular somatostatin stimulates gastric acid secretion in the dog, in: Regulatory Peptides in Digestive, Nervous and Endocrine Systems, INSERM Symposium No. 25, eds. M.J.M. Lewin and S. Bonfils (Elsevier Science Publishers BV, Amsterdam) p. 323.
19. Paxinos, G. and C. Watson, 1986, The rat brain in stereotaxic coordinates (Academic Press, Orlando) p. 1.
20. Pérez, J. and D. Hoyer, 1995, Co-expression of somatostatin SSTR-3 and SSTR-4 receptor messenger RNAs in the rat brain, Neuroscience 64, 241.
21. Pless, J., W. Bauer, U. Briner, W. Doepfner, P. Marbach, R. Maurer, T.J. Petcher, J.C. Reubi and J. Vonderscher, 1986, Chemistry and pharmacology of SMS 201-995, a long-acting octapeptide analogue of somatostatin, Scand. J. Gastroenterol. 21 (Suppl. 119), 54.
22. Raynor, K., W.A. Murphy, D.H. Coy, J.E. Taylor, J.P. Moreau, K. Yasuda, G.I. Bell and T. Reisine, 1993a, Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides, Mol. Pharmacol. 43, 838.
23. Raynor, K., A.M. O'Carroll, H. Kong, K. Yasuda, L.C. Mahan, G.I. Bell and T. Reisine, 1993b, Characterization of cloned somatostatin receptors SSTR4 and SSTR5, Mol. Pharmacol. 44, 385.
24. Reisine, T., G.I. Bell, 1995, Molecular biology of somatostatin receptors, Endocrinol. Rev. 16, 427.
25. 2+ channels, Neuroendocrinology 54, 559.
26. Rossowski, W.J. and D.H. Coy, 1993, Potent inhibitory effects of a type four receptor-selective somatostatin analog on rat insulin release, Biochem. Biophys. Res. Commun. 197, 366.
27. Rossowski, W.J., Z.-F. Gu, U.S. Akarca, R.T. Jensen and D.H. Coy, 1994, Characterization of somatostatin receptor subtypes controlling rat gastric acid and pancreatic amylase release, Peptides 15, 1421.
28. Senaris, R.M., P.P.A. Humphrey and P.C. Emson, 1994, Distribution of somatostatin receptors 1, 2 and 3 mRNA in rat brain and pituitary, Eur. J. Neurosci. 6, 1883.
29. Stephens, R.L., Jr., 1991, Disparate effects of intracisternal RX 77368 and ODT8-SS on gastric acid secretion and serotonin release: role of adrenal catecholamines, Reg. Pept. 36, 21.
30. Taché, Y., J. Rivier, W. Vale and M. Brown, 1981, Is somatostatin or a somatostatin-like peptide involved in central nervous system control of gastric secretion?, Reg. Pept. 1, 307.
31. Tannenbaum, G.S. and Y.C. Patel, 1986, On the fate of centrally administered somatostatin in the rat: massive hypersomatostatinemia resulting from leakage into the peripheral circulation has effects on growth hormone secretion and glucoregulation, Endocrinology 118, 2137.
32. Yamada, Y., S. Kagimoto, A. Kubota, K. Yasuda, K. Masuda, Y. Someya, Y. Ihara, Q. Li, H. Imura, S. Seino and Y. Seino, 1993, Cloning, function expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype, Biochem. Biophys. Res. Commun. 195, 844.
33. Yang, H. and Y. Taché, 1994, Prepro-TRH-(160-169) potentiates gastric acid secretion stimulated by TRH microinjected into the dorsal motor nucleus of the vagus, Neurosci. Lett. 174, 43.
34. Yoneda, M. and Y. Taché, 1995, The somatostatin analog, SMS 201-995 stimulates gastric acid secretion via the dorsal vagal complex and inhibits it via the hypothalamus in anesthetized rats, Br. J. Pharmacol. 116, 2303.
35. Yoneda, M., H. Raybould and Y. Taché, 1991, Central action of somatostatin analog, SMS 201-995, to stimulate gastric acid secretion in rats, Peptides 12, 401.