Intracellular pH regulation in human preimplantation embryos

Human Reproduction

Volumn 15, Issue 4, 2000, Pages 896-904

  Phillips, Karen P ^a   Léveillé, Marie Claude ^b   Claman, Paul ^c   Bauz, J M ^d  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b Division of Reproductive Medicine   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Cl exchanger; Embryo; H+ antiporter; HCO3 ; Na+; pH

Indexed keywords

CARBONIC ACID; CHLORIDE ION; PROTON; SODIUM ION;

ACIDOSIS; ALKALOSIS; ANION EXCHANGE; ARTICLE; CATION EXCHANGE; CELL PH; HOMEOSTASIS AND REGULATION; HUMAN; NORMAL HUMAN; PH; PREIMPLANTATION EMBRYO;

EID: 0342700228     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/15.4.896     Document Type: Article

References (30)

1. - exchanger (AE) gene family. Anna. Rev. Physiol, 53, 549-564.
2. - exchanger gene family. Cell Physiol. Biochem., 4, 265-281.
3. Baltz, J.M. and Phillips, K.P. (1998) Intracellular ion measurements in single eggs and embryos using ion-sensitive fluorophores. In Richter, J.D. (ed.), Advances in Molecular Biology, A Comparative Methods Approach to the Study of Oocytes and Embryos. Oxford University Press, Oxford.
4. + antiport activity in the two-cell mouse embryo. Dev. Biol., 138, 421-429.
5. Baltz, J.M., Biggers, J.D. and Lechene, C. (1991) Relief from alkaline load in 2-cell stage mouse embryos by bicarbonate-chloride exchange. J. Biol. Chem., 266, 17212-17217.
6. + exchanger isoforms to preimplantation development of the mouse. .A/oJ. Keprod. Dev., 50, 146-153.
7. Ben-Yosef, D., Oron, Y. and Shalgi, R. (1996) Intracellular pH of rat eggs is not affected by fertilization and the resulting calcium oscillations. Biol. Repmd., 55, 461-468.
8. 3 and metabolic inhibitors. J. Gen. Physiol., 67, 91-112.
9. Dale, B., Menezo.Y., Cohen, J., DiMatteo, L. and Wilding, M. (1998) Intracellular pH regulation in the human oocyte. Hum. Reprod., 13,964-970.
10. + exchange. Am. J. Physiol., 273, C404-419.
11. + exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation. Biochim. Biophys. Ada, 988, 73-97.
12. House, C.R. (1994) Confocal ratio imaging of intracellular pH in unfertilized mouse oocytes. Zygote, 2, 37-45.
13. +) antiporter. Biol. Reprod. Dev. Biol., 59, 1483-1490.
14. + antiporter activity in hamster embryos is activated during fertilization. Dev. Biol., 208,244-252.
15. Lane, M., Baltz, J.M. and Bavister, B.D. (1999b) Bicarbonate/chloride exchange regulates intracellular pH of embryos not oocytes of hamster. Biol. Reprod., 61, 452-457.
16. Lawitts, J.A. and Biggers, J.D. (1993) Culture of preimplantation embryos. Meth. Enzymol., 225, 153-164.
17. Maas, D., Storey, B. and Mastroianni, L. (1977) Hydrogen ion and carbon dioxide content in the oviductal fluid of the rhesus monkey. Fertil. Steril., 28, 981-985.
18. Maas, D.H., Stein, B., Metzger, H. and Schneider, U. (1987) Influence of microsurgical reanastomosis of the fallopian tube on luminal pH and PO2 and on the fertilization rate and embryo development in the rabbit oviduct. Eur. J. Obstet. Gynecol. Reprod. Biol., 24, 73-83.
19. - exchange modulates intracellular pH in rat type II alveolar epithelial cells. J. Biol. Chem., 263, 5599-5606.
20. + exchangers of mammalian cells. J. Biol. Chem., 272, 22373-22376.
21. Phillips, K.P. and Baltz, J.M. (1996) An intracellular pH increase does not accompany egg activation in the mouse. Mol. Reprod. Dev., 45, 52-60.
22. - exchange is activated during early mouse zygote development. Dev. Biol., 208, 392-405.
23. Phillips, K.P., Zhou, W.L. and Baltz, J.M. (1998) Fluorophore toxicity in mouse eggs and embryos. Zygote, 6, 113-123.
24. Rattanachaiyanont, M., Leader, A. and Léveillé, M-C. (1999) Lack of correlation between oocyte-corona-cumulus complex morphology and nuclear maturity of oocytes collected in stimulated cycles for intracytoplasmic sperm injection. Fertil. Steril., 71, 937-940.
25. Roos, A. and Boron, W.F. (1981) Intracellular pH. Physiol. Rev., 61, 296-434.
26. Thomas, J.A., Buchsbaum, R.N., Zimniak, A. and Racker, E. (1979) Intracellular pH measurements in Erhlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry, 18, 2210-2218.
27. Vaughan-Jones, R.D. (1988) Regulation of intracellular pH in cardiac muscle. In Bock, G.and Marsh, J. (eds), Proton Passage Across Cell Membranes. Ciba Foundation/ Wiley, Sussex, UK, pp. 23-46.
28. Zhao, Y. and Baltz, J.M. (1996) Characterization of bicarbonate/chloride exchange during preimplantation mouse embryo development. Am. J. Physiol., Cell Physiol., 271, C1512-C1520.
29. Zhao, Y., Chauvet, P.J-P., Alper, S.L. and Baltz, J.M. (1995) Expression and function of bicarbonate/chloride exchangers in the preimplantation mouse embryo. J. Biol. Chem., 270, 24428-24434.
30. - transport across the trophectoderm of the mouse blastocyst. Dev. Biol., 189, 148-160.