TNF-α and IL-1α induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengers

Cytokine

Volumn 12, Issue 7, 2000, Pages 986-991

  Böhler, Torsten ^a,b   Waiser, Johannes ^a   Hepburn, Helen ^a   Gaedeke, Jens ^a   Lehmann, Christine ^a   Hambach, Pia ^a   Budde, Klemens ^a   Neumayer, Hans Hellmut ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Apoptosis; Hydrogen peroxide; IL 1 ; Lipid peroxidation; Mesangial cells; TNF

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; INTERLEUKIN 1; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOCHEMISTRY; CELL STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION; LIPID PEROXIDATION; MESANGIUM CELL; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECOND MESSENGER;

EID: 0342656225     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1999.0633     Document Type: Article

References (15)

1. Savill J (1995) Apoptosis: will cell death add life to nephrology? Nephrol Dial Transplant 10:1977-1979 .
2. Baker AJ, Mooney A, Hughes J, Lombardi D, Johnson RJ, Savill J (1994) Mesangial cell apoptosis: the major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis. J Clin Invest 5:2105-2116.
3. Kluth DC, Rees AJ (1996) Inhibiting inflammatory cytokines. Semin Nephrol 16:576-582.
4. Radeke HH, Meier B, Topley N, Flöge J, Habermehl GG, Resch K (1990) Interleukin 1-α and tumor necrosis factor-α induce oxygen radical production in mesangial cells. Kidney Int 37:767-775.
5. Sugiyama H, Kashihara N, Makino H, Yamasaki Y, Ota Z (1996) Reactive oxygen species induce apoptosis in cultured human mesangial cells. J Am Soc Nephrol 7:2357-2363.
6. Meyer TN, Gloy J, Hug MJ, Greger R, Schollmeyer P, Pavenstadt H (1996) Hydrogen peroxide increases the intracellular calcium activity in rat mesangial cells in primary culture. Kidney Int 49:388-395.
7. Shaw S, Naegeli P, Etter JD, Weidmann P (1995) Role of intracellular signaling pathways in hydrogen peroxide-induced injury to rat glomerular mesangial cells. Clin Exp Pharmacol Physiol 22:924-933.
8. Guo YL, Baysal K, Kang B, Yang LJ, Williamson JR (1998) Correlation between sustained c-jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-α in rat mesangial cells. J Biol Chem 7:4027-4034.
9. Lo YC, Wong JM, Cruz TF (1996) Reactive oxygen species mediate cytokine activation of c-jun NH2-terminal Kinases. J Biol Chem 271:15703-15707.
10. Liu ZH, Striker GE, Stetler-Stephenson M, Fukushima P, Patel A, Striker LJ (1996) TNF-alpha and IL-1 alpha induce mannose receptors and apoptosis in glomerular mesangial but not endothelial cells. Am J Physiol 270:1595-1601.
11. Zoja C, Rambaldi A, Remuzzi G (1993) Interleukin-1 and glomerular mesangial cells. Ren Physiol Biochem 16:89-92.
12. Budde K, Neumayer HH, Salant DJ, Cybulsky AV, Coleman DL, Sterzel RB (1997) Glomerular epithelial cell products stimulate mesangial cell proliferation in culture. Kidney Int 52:733-741.
13. Budde K, Coleman DL, Lacy J, Sterzel RB (1989) Rat mesangial cells produce granulocyte-macrophage colony-stimulating factor. Am J Physiol 257:1065-1078.
14. McGahon AJ (1995) The end of the (cell) line: methods for the study of apoptosis in vitro. In Schwartz LM, Osborne BA (eds) Methods in Cell Biology. Academic Press, Boston, pp 153-185.
15. Chromczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.