Induced accumulation of triterpenoids in Scutellaria baicalensis suspension cultures using a yeast elicitor

Biotechnology Letters

Volumn 22, Issue 13, 2000, Pages 1071-1075

  Yoon, Hee Jeong ^a   Kim, Hye Kyong ^a   Ma, Choong Je ^a   Huh, Hoon ^a  

^a Seoul National University   (South Korea)

Author keywords

Elicitation; Octadecanoid pathway; Phospholipase A2; Scutellaria baicalensis; Triterpenoids

Indexed keywords

ARISTOLOCHIC ACID; OLEANOLIC ACID; PHOSPHOLIPASE A2; TRITERPENOID; URSOLIC ACID;

ARTICLE; CELL SUSPENSION; CONCENTRATION (PARAMETERS); ENZYME ACTIVITY; NONHUMAN; PHYTOCHEMISTRY; SIGNAL TRANSDUCTION; YEAST;

EID: 0342646895     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005610400511     Document Type: Article

References (22)

1. Brindle PA, Kuhn PJ, Threlfall DR (1988) Biosynthesis and metabolism of sesquiterpenoid phytoalexins and triterpenoids in potato cell-suspension cultures. Phytochemistry 27: 133-150.
2. Chapman KD (1998) Phospholipase activity during plant growth and development and in response to environmental stress. Trends Plant Sci. 3: 419-426.
3. Creelman RA, Mullet JE (1995) Jasmonic acid distribution and action in plants: regulation during development and response to biotic and abiotic stress, Proc. Natl. Acad. Sci. USA 92: 4114-4119.
4. Creelman RA, Mullet JE (1997) Biosynthesis and action of jasmonates in plants, Annu. Rev. Plant Physiol. Plant Mol. Biol. 48: 355-381.
5. Elsaady D, Simon A, Jayatvignoles C, Chulia AJ, Delage C (1996) MCF-7 Cell-cycle arrested at G1 through ursolic acid, and increased reduction of tetrazolium salts. Anticancer Res. 16: 481-486.
6. Gundlach H, Muller MJ, Kutchan TM, Zenk MH (1992) Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures. Proc. Natl. Acad. Sci. USA 89: 2389-2393.
7. Hsu HY (1954) Chinese drugs Huang-Lien (Coptis teeta), Huang-Chin (Scutellaria baicalensis) and Ko-Kun (Pueraria thunberriana). IV. Antibacterial activity of wogonin from Scutellaria baicalensis. J. Taiwan Pharm. Assoc. 6: 7-10.
8. 2's. FEBS Lett. 343: 213-218.
9. Montagnac A, Provost JP, Litaudon M, Pais M (1997) Antimitotic and cytotoxic constituents of Myodocarpus gracilis. Planta Med. 63: 365-366.
10. Morimoto S, Tateishi N, Matsuda T, Tanaka H, Taura F, Furuya N, Matsuyama N, Shoyama Y (1998) Novel hydrogen peroxide metabolism in suspension cells of Scutellaria baicalensis Georgi. J. Biol. Chem. 273: 12606-12611.
11. Mueller MJ, Brodschelm W, Spannagl E, Zenk MH (1993) Signaling in the elicitation process is mediated through the octadecanoid pathway leading to jasmonic acid. Proc. Natl. Acad. Sci. USA 90:7490-7494.
12. Radosevich MB, Delfel NE, England R (1985) Gas chromatography-mass spectrometry of oleanane- and ursane-type triterpenes-application to Chenopodium quinoa triterpenes. Phytochemistry 24: 2063-2066.
13. Schenk RU, Hildebrandt AC (1972) Medium and techniques for induction and growth of monocotyledons and dicotyledonous plant cell cultures. Can. J. Bot. 50: 199-204.
14. Seo WT, Park YH, Choe TB (1993) Identification and production of flavonoids in a cell suspension culture of Scutellaria baicalensis G. Plant Cell Rep. 12: 414-417.
15. Threlfall DR, Whitehead IM (1988) Coordinated inhibition of squalene synthetase and induction of enzymes of sesquiterpenoid phytoalexin biosynthesis in cultures of Nicotiana tabacum Phytochemistry 27: 2567-2580.
16. van der Heijden R, Threlfall DR, Verpoorte R, Whitehead IM (1989) Regulation and enzymology of pentacyclic triterpenoid phytoalexin biosynthesis in cell-suspension cultures of Tabernaemontana divaricata. Phytochemistry 28: 2981-2988.
17. van der Heijden R, Verheij R, Schripsema J, Baerheim Svendsen A, Verpoorte R, Harkes PAA (1988) Induction of triterpene biosynthesis by biotic elicitors in suspension cultures of Tabernaemontana species. Plant Cell Rep. 7: 51-54.
18. Verpoorte R, van der Heijen R, ten Hoopen HJG, Memelink J (1999) Metabolic engineering of plant secondary metabolites pathways for the production of fine chemicals. Biotechnol. Lett. 21: 467-479.
19. Vick BA (1993) Oxygenated fatty acids of the lipoxygenase pathway. In: Moore TS, ed. Lipid Metabolism in Plants. London: CRC Press, pp. 167-191.
20. Vick BA, Zimmerman DC (1984) Biosynthesis of jasmonic acid by several plant species. Plant Physiol. 64: 203-205.
21. Yamamoto H, Ichimura M, Inoue K (1995) Stimulation of prenylated flavone production by mannans and acidic polysaccharides in callus culture of Sophorae flavescens. Phytochemistry 40: 77-81.
22. Yoshikawa M, Yamaoka N, Takeuchi Y (1993) Elicitors: their significance and primary modes of action in the induction of plant defense reactions. Plant Cell Physiol. 34: 1163-1173.