Action of the extract of Drymis winteri on contraction induced by inflammatory mediators, compound 48/80 and ovalbumin of the guinea-pig trachea in vitro

General Pharmacology

Volumn 28, Issue 5, 1997, Pages 699-704

  El Sayah, Mariem ^a   Cechinel Filho, Valdir ^b   Yunes, Rosendo A ^a   Calixto, João B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

Author keywords

allergy; asthma; capsaicin; compound 48 80; contraction; crude extract; Drymis winteri; guinea pig trachea; ovalbumin; prostanoids; tachykinins

Indexed keywords

BRADYKININ; CAPSAICIN; COMPOUND 48-80; HISTAMINE; NEUROKININ A; OVALBUMIN; PLANT EXTRACT; PROSTAGLANDIN E2; PROSTANOID; SUBSTANCE P; TACHYKININ; THROMBOXANE A2;

ALLERGY; ANIMAL TISSUE; ARTICLE; ASTHMA; CONCENTRATION RESPONSE; DOSE TIME EFFECT RELATION; DRUG ANTAGONISM; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; TRACHEA; TRADITIONAL MEDICINE;

ACETYLCHOLINE; ANIMALS; DRUG INTERACTIONS; FEMALE; GUINEA PIGS; HISTAMINE; INFLAMMATION MEDIATORS; KININS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; OVALBUMIN; P-METHOXY-N-METHYLPHENETHYLAMINE; PLANT EXTRACTS; PLANTS, MEDICINAL; PROSTAGLANDINS; TRACHEA;

EID: 0342618523     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(96)00361-8     Document Type: Article

References (43)

1. Andersson P. and Bergstrand H. (1981) Antigen-induced bronchial anaphylaxis in actively sensitized guinea-pig: Effect of long-term treatment with sodium cromoglycate and aminophylline. Br. J. Pharmac. 74, 601.
2. Appel H. H., Brooks C. J. W. and Overton K. H. (1959) The constitution and stereochemistry of drimenol, a novel bicyclic sesquiterpenoid. J. Chem. Soc, 673, 3322-3332.
3. Appel H. H. and Dohr R. (1958) Terpenos del canelo chileno III. Scientia 25, 135-142.
4. Arunlakshana O. and Schild H.O. (1959) Some quantitative uses of drug antagonists. Br. J. Pharmac. 14, 48-58.
5. 2)-receptor gene expression in inflammatory airway diseases. Am. J. Physiol. 269, 309-317.
6. Barnes P. J. (1992) Bradykinin and asthma. Thorax 47, 979.
7. Beer D. J., Matloff S. M. and Rocklin, R. E. (1984) The influence of histamine on immune and inflammation responses. Adv. Immunol. 35, 209-268.
8. Bevan S., Hothi S., Hughes G., James I. F., Rang H. P., Shah K., Walpole C. S. J. and Yeats J. C. (1992) Capsazepine: A competitive antagonist of the sensory neurone excitant capsaicin. Br. J. Pharmac. 107, 544-552.
9. Brown G. D. (1994) Drimendiol, a sesquiterpene from Drymis winteri. Phytochemistry 35, 975-977.
10. Busse W. W. and Sedgwick J. B. (1994) Eosinophil eicosanoid relations in allergic inflammation of the airways. Adv. Prostagland. Thrombox. Leuk. Res. 22, 241-249.
11. Calixto J. B., Yunes R. A. Bella Cruz A. and Medeiros Y. S. (1992) Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea-pig trachea. Agents Actions 36, 222-229.
12. Cortés M. M. and Oyarzun M. L. (1981) Tadeonal and isotadeonal from Drymis winteri. Fitoterapia 52, 33-35.
13. Cruz A. and Silva M. (1973) Further terpenoids and phenolics of Drymis winteri. Phytochemistry 12, 2549-2550.
14. Ellis J. L. and Undem B. J. (1994) Inhibition by Capsazepine of resiniferatoxin and capsaicin-induced contractions of guinea-pig trachea. J. Pharmac. Exp. Ther. 268, 85-89.
15. 2 receptors mediate tachykinin and resiniferatoxin-induced bronchospasm in guinea-pigs. Am. Rev. Respir. Dis. 148, 915-921.
16. Frossard N. and Advenier C. (1991) Tachykinin receptors and the airways. Life Sci. 49, 1941-1953.
17. Hamberg M., Svensson J. and Samuelsson, B. (1975) Thromboxane: A new group of biologically active compounds derived from prostaglandin endoperoxides. Proc. Natl. Acad. Sci. USA 72, 2994-2998.
18. Honda I., Kohrogi H., Yamaguchi T., Ando M. and Araki, S. (1991) Enkephalinase inhibitor potentiates substance P- and capsaicin-induced bronchial contractions in humans. Am. Rev. Respir. Dis. 143, 1416-1418.
19. Karlsson J. A. and Persson C. G. A. (1989). Novel peripheral neurotransmitters and control of the airways. Pharmac. Ther. 43, 397-423.
20. 2 or leukotrienes. Br. J. Pharmac. 110, 657.
21. Leurs R., Smitt M. J. and Timmerman H. (1995) Molecular pharmacological aspects of histamine receptors. Pharmac. Ther. 66, 413-463.
22. Lewis G. P., Nouri A. M. E., Fan D. T. P. and Gordon D. (1981) Effect of histamine and related compounds on the immune response. Adv. Pharmac. Ther. II 14, 159-169.
23. Lundberg J. M., Saria A., Brodin E., Rosell S. and Folkers K. (1983) A substance P antagonist inhibits vaguely induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea-pig. Proc. Natl. Acad. Sci. USA. 80, 1120-1124.
24. Maggi C. A. (1990) Tachykinin receptors in the airways and lung: What should we block? Pharmac. Res. 22, 527-540.
25. Maggi C. A., Gianchetti A., Dey R. D. and Said, S. I. (1995) Neuropeptides as regulators of airway function: Vasoactive intestinal peptide and the tachykinins. Physiol. Rev. 75, 277-322.
26. Maling H. M., Webster M. E., Williams M. A, Saul W. and Anderson W. (1974) Inflammation induced by histamine, serotonin, bradykinin and compound 48/80 in the rat: Antagonists and mechanisms of action. J. Pharmac. Exp. Ther. 191, 300-310.
27. Maron Z. and Casale T. B. (1983) Mast cells and their mediators. Ann. Allerg. 50, 367-370.
28. Morton J. F. (1981). Atlas of Medicinal Plants in Middle America-Bahamas to Yucatan. Charles C. Thomas, Springfield, IL.
29. Noveral J. P. and Grunstein M. M. (1995) Tachykinin regulation of airway smooth muscle cell proliferation. Am. J. Physiol. 269, 339-343.
30. O'Byrne P. M., Dolovich J. and Hargreave F. E. (1987) Late asthmatic responses. Am. Rev. Respir. Dis. 136, 740-748.
31. Paton W. D. M. (1951) Compound 48/80: A potent histamine liberator. Br. J. Pharmac. 6, 499-508.
32. Pauwels R. A., Joos G. F. and Kips, J. C. (1995) Leukotrienes as therapeutic target in asthma. Allergy 50, 615-622.
33. Pretolani M., Lefort J., Dumarey C. and Vargaftig B. B. (1989). Role of lipoxygenase metabolites for the hyper-responsiveness to platelet-activating factor of lungs from actively sensitized guinea-pigs. J. Pharmac. Exp. Ther. 248, 353-359.
34. Ricciardolo F. L., Nadel J. A., Graf P. D., Bertrand C., Yoshihara S. and Geppetti P. (1994). Role of kinins in anaphylactic-induced bronchoconstriction mediated by tachykinins in guinea-pigs. Br. J. Pharmac. 113, 508-512.
35. Santing R. E., Schraa E. O., Wachters A., Olymulder C. G., Zaagsma J. and Meurs H. (1994) Role of histamine in allergen-induced asthmatic reactions, bronchial hyperreactivity and inflammation in unrestrained guinea pigs. Eur. J. Pharmac. 254, 49-57.
36. 2 analogue in guinea- pigs. Allergy 47, 181-184.
37. Schelemper V. and Calixto J. B. (1994) Nitric oxide pathway-mediated relaxant effect of bradyklnin in the guinea pig isolated trachea. Br. J. Pharmac. 111, 83-88.
38. Schelemper V. and Calixto J. B. (1995) Mechanisms involved in the relaxant response of bradykinin in epithelium intact strips of the guinea-pig trachea. Eur. J. Pharmac. 282, 177-184.
39. Schlosberg M., Liu M. C. and Bochner B. S. (1993) Pathophysiology of asthma. Immunology and Allerg Clin of North America. 13, 721-743.
40. 2: Effects on airway and vascular smooth muscle. Prostaglandins 14, 425-436.
41. 3H] resiniferatoxin binding to central (spinal cord, dorsal root ganglia) and peripheral (urinary bladder, airways) vanilloid (capsaicin) receptors in the rat. J. Pharmac. Exp. Ther. 267, 728-733.
42. Thien F. C. K. and Walters E. H. (1995) Eicosanoids and asthma: An update. Prostagland., Leuk. Essen. Fatty Acids 52, 271-288.
43. Torres R., Pardo F. and Velasco, M.V. (1992). Flavonoid from Drymis winteri. Fitoterapia 58, 553-558.