Correlation of the exon/intron organization to the secondary structures of the protease domain of mouse meprin α subunit

Gene

Volumn 189, Issue 1, 1997, Pages

  Jiang, Weiping ^a   Flannery, Angela V ^b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Astacin family; Meprin gene; Metalloendopeptidase

Indexed keywords

MEPRIN; PROTEIN SUBUNIT; PROTEINASE;

AMINO ACID SEQUENCE; ARTICLE; COMPUTER MODEL; EXON; GENE STRUCTURE; INTRON; MOUSE; NONHUMAN; ORGANIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; BASE COMPOSITION; BASE SEQUENCE; CLONING, MOLECULAR; ENDOPEPTIDASES; EVOLUTION, MOLECULAR; EXONS; INTRONS; METALLOENDOPEPTIDASES; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0342602071     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00834-7     Document Type: Article

References (42)

1. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A. and Struhl, K. (1995) Current Protocols in Molecular Biology. John Wiley & Sons, New York.
3. Bode, W., Gomis-Rüth, F.X., Stöcker, W. (1993) Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'. FEBS Lett. 331, 134-140.
4. Bond, J.S. and Beynon, R.J. (1995) The astacin family of metalloendopeptidases. Protein Sci. 4, 1247-1261.
5. Bond, J.S., Beynon, R.J., Reckelhoff, J.F. and David, C.S. (1984) Mep-1 gene controlling a kidney metalloendopeptidase is linked to the major histocompatibility complex in mice. Proc. Natl. Acad. Sci. USA 81, 5542-5545.
6. Bond, J.S., Rojas, K., Overhauser, J., Zoghbi, H.Y. and Jiang, W. (1995) The structural genes, MEP1A and MEP1B, for the α and β subunits of the metalloendopeptidase meprin map to human chromosomes 6p and 18q, respectively. Genomics 25, 300-303.
7. Childs, S.R. and O'Connor, M.B. (1994) Two domains of the tolloid protein contribute to its unusual genetic interaction with decapentaplegic. Dev. Biol. 162, 209-220.
8. Corbell, D., Gaudoux, F., Wainwright, S., Ingram, J., Kenny, A.J., Boileau, G. and Crine, P. (1992) Molecular cloning of the α subunit of rat endopeptidase-24.18 (endopeptidase-2) and co-localization with endopeptidase-24.11 in rat kidney by in situ hybridization. FEBS Lett. 309, 203-208.
9. Dietrich, J.M., Jiang, W. and Bond, J.S. (1996) (1996) A novel meprin β′ mRNA in mouse embryonal and human colon carcinoma cells. J. Biol. Chem. 271, 2271-2278.
10. Doolittle, R.F. (1995) The multiplicity of domains in proteins. Annu. Rev. Biochem. 64, 287-314.
11. Dumermuth, E., Sterchi, E.E., Jiang, W., Wolz, R.L., Bond, J.S., Flannery, A.V. and Beynon, R.J. (1991) The astacin family of metalloendopeptidases. J. Biol. Chem. 266, 21381-21385.
12. Dumermuth, E., Eldering, J.A., Grünberg, H., Jiang, W. and Sterchi, E.E. (1993) Cloning of the PABA peptide hydrolase alpha subunit (PPHα) from human small intestine and its expression in COS-1 cells. FEBS Lett. 335, 367-375.
13. Finelli, A.L., Bossie, C.A., Xie, T. and Padgett, R.W. (1994) Mutational analysis of the Drosophila tolloid gene, a human BMP-1 homolog. Development 120, 861-870.
14. Fleischmann, R.D., Adams, M.D., White, O., Clayton, R.A., Kirkness, E.F., Kerlavage, A.R., Bult, C.J., Tomb, J.-F., Dougherty, B.A., Merrick, J.M., McKenney, K., Sutton, G., FitzHugh, W., Fields, C., Gocayne, J.D., Scott, J., Shirley, R., Liu, L.-I., Glodek, A., Kelley, J.M., Weidman, J.F., Phillips, C.A., Spriggs, T., Hedblom, E., Cotton, M.D., Utterback, T.R., Hanna, M.C., Nguyen, D.T., Saudek, D.M., Brandon, R.C., Fine, L.D., Fritchman, J.L., Fuhrmann, J.L., Geoghagen, N.S.M., Gnehm, C.L., McDonald, L.A., Small, K.V., Fraser, C.M., Smith, H.O. and Venter, J.C. (1995) Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269, 496-512.
15. Fraser, C.M., Gocayne, J.D., White, O., Adams, M.D., Clayton, R.A., Fleischmann, R.D., Bult, C.J., Kerlavage, A.R., Sutton, G., Kelley, J.M., Fritchman, J.L., Weidman, J.F., Small, K.V., Sandusky, M., Fuhrmann, J., Nguyen, D., Utterback, T.R., Saudek, D.M., Phillips, C.A., Merrick, J.M., Tomb, J.-F., Dougherty, B.A., Bott, K.F., Hu, P.-C., Lucier, T.S., Peterson, S.N., Smith, H.O., Hutchison III, C.A. and Venter, J.C. (1995) The minimal gene complement of Mycoplasma genitalium. Science 270, 397-403.
16. Ghiglione, C., Lhomond, G., Lepage, T. and Gache, C. (1994) Structure of the sea urchin hatching enzyme gene. Eur. J. Biochem. 219, 845-854.
17. Gilbert, W. and Glynias, M. (1993) On the ancient nature of introns. Gene 135, 137-144.
18. Gorbea, C.M., Marchand, P., Jiang, W., Copeland, N.G., Gilbert, D.J., Jenkins, N.A. and Bond, J.S. (1993) Cloning, expression, and chromosomal localization of the mouse meprin β subunits. J. Biol. Chem. 268, 21035-21043.
19. Jiang, W. and Bond, J.S. (1992) Families of metalloendopeptidases and their relationships. FEBS Lett. 312, 110-114.
20. Jiang, W. and Bond, J.S. (1996) Astacin family of metalloendopeptidases. In: Hooper, N.M. (Ed.), Zinc Metalloproteases in Health and Disease. Taylor and Francis, London.
21. Jiang, W., Gorbea, C.M., Flannery, A.V., Beynon, R.J., Grant, G.A. and Bond, J.S. (1992) The α subunit of meprin A: molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the α and β subunits. J. Biol. Chem. 267, 9185-9193.
22. Jiang, W., Sadler, P.M., Jenkins, N.A., Gilbert, D.J., Copeland, N.G. and Bond, J.S. (1993) Tissue-specific expression and chromosomal localization of the α subunit of mouse meprin A. J. Biol. Chem. 268, 10380-10385.
23. Jiang, W., Dewald, G., Brundage, E., Mücher, G., Schildhaus, H.-U., Zerres, K. and Bond, J.S. (1995) Fine mapping of MEP1A, the gene encoding the α subunit of the metalloendopeptidase meprin, to human chromosome 6p21. Biochem. Biophys. Res. Commun. 216, 630-635.
24. Johnson, G.D. and Hersh, L.B. (1992) Cloning a rat meprin cDNA reveals the enzyme is a heterodimer. J. Biol. Chem. 267, 13505-13512.
25. Palmer, J.D. and Logsdon Jr., J.M. (1991) The recent origins of introns. Curr. Opin. Gen. Dev. 1, 470-477.
26. Patthy, L. (1987) Intron-dependent evolution: preferred types of exons and introns. FEBS Lett. 214, 1-7.
27. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
28. Shimell, M.J., Ferguson, E.L., Childs, S.R. and O'Connor, M.B. (1991) The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1. Cell 67, 461-481.
29. Spencer-Dene, B., Thorogood, P., Nair, S., Kenny, J., Harris, M. and Henderson, B. (1994) Distribution of, and a putative role for, the cell surface neutral metalloendopeptidases during mammalian craniofacial development. Development 120, 3213-3226.
30. Stoltzfus, A., Spencer, D.F., Zuker, M., Logsdon, J.M. and Doolittle, W.F. (1994) Testing the exon theory of genes: the evidence from protein structure. Science 265, 202-207.
31. Stöcker, W., Gomis-Rüth, F.-X., Bode, W. and Zwilling, R. (1993) Implications of the three-dimensional structure of astacin for the structure and function of the astacin family of zinc-endopeptidases. Eur. J. Biochem. 214, 215-231.
32. Stöcker, W., Grams, F., Baumann, R., Reinemer, P., Gomis-Rüth, F.-X., McKay, D.B. and Bode, W. (1995) The metzincins- Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases. Protein Sci. 4, 823-840.
33. Takahara, K., Lee, S., Wood, S. and Breenspan, D.S. (1995) Structural organization and genetic localization of the human bone morphogenetic protein 1/mammalian tolloid gene. Genomics 29, 9-15.
34. Thompson, J.D., Higgins, D.G. and Gibson, T.J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673-4680.
35. Tarentino, A.L., Quinones, G., Grimwood, B.G., Hauer, C.R., Plummer Jr., T.H. (1995) Molecular cloning and sequence analysis of flavastacin: an O-glycosylated prokaryotic zinc metalloendopeptidase. Arch. Biochem. Biophys. 319, 281-285.
36. Titani, K., Torff, H.-J., Hormel, S., Kumar, S., Walsh, K.A., Rödl, J., Neurath, H. and Zwilling, R. (1987) Amino acid sequence of a unique protease from the crayfish Astacus fluviatilis. Biochemistry 26, 222-226.
37. Weber, K. and Kabsch, W. (1994) Intron positions in actin genes seem unrelated to the secondary structure of the protein. EMBO J. 13, 1280-1286.
38. Wilson, R., Ainscough, R., Anderson, K., Baynes, C., Berks, M., Bonfield, J., Burton, J., Connell, M., Copsey, T., Cooper, J., Coulson, A., Craxton, M., Dear, S., Du, Z., Durbin, R., Favello, A., Fulton, L., Gardner, A., Green, P., Hawkins, T., Hillier, L., Jier, M., Johnston, L., Jones, M., Kershaw, J., Kirsten, J., Laister, N., Latreille, P., Lightning, J., Lloyd, C., McMurray, A., Mortimore, B., O'Callaghan, M., Parsons, J., Percy, C., Rifken, L., Roopra, A., Saunders, D., Shownkeen, R., Smaldon, N., Smith, A., Sonnhammer, E., Staden, R., Sulston, J., Thierry-Mieg, J., Thomas, K., Vaudin, M., Vaughan, K., Waterston, R., Watson, A., Weinstock, L., Wilkinson-Sproat, J. and Wohldman, P. (1994) 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature 368, 32-38.
39. Wozney, J. M., Rosen, V., Celeste, A.J., Mitsock, L.M., Whitters, M.J., Kriz, R.W., Hewick, R.M. and Wang, E.A. (1988) Novel regulators of bone formation: molecular clones and activities. Science 242, 1528-1534.
40. Yamaguchi, T., Fukase, M., Sugimoto, T., Kido, H. and Chihara, K. (1994) Purification of meprin from human kidney and its role in parathyroid hormone degradation. Biol. Chem. Hoppe-Seyler 375, 821-824.
41. Yasumasu, S., Yamada, K., Akasaka, K., Mitsunaga, K., Iuchi, I., Shimada, H. and Yamagami, K. (1992) Ioslation of cDNAs for LCE and HCE, two constituent proteases of the hatching enzyme of Oryzias latipes, and concurrent expression of their mRNAs during development. Dev. Biol. 153, 250-258.
42. Yasumasu, S., Iuchi, I. and Yamagami, K. (1994) cDNA and the genes of HCE and LCE, two constituents of the medaka hatching enzyme. Dev. Growth Differ. 36, 241-250.