Concentration-dependent effects of hematopoietic growth factors during in vitro expansion of mouse stem cells and progenitor cells

Growth Factors

Volumn 14, Issue 1, 1997, Pages 59-66

  Jönsson, Jan Ingvar ^a,b   Nilsson, Kenneth ^a   Phillips, Robert A ^b  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Cytokine mediated expansion; Hematopoietic stem cell; IL 1; IL 3

Indexed keywords

HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 1; INTERLEUKIN 3; INTERLEUKIN 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; FETUS; HEMATOPOIETIC STEM CELL; LIVER TRANSPLANTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; STEM CELL;

ANIMALIA;

EID: 0342601438     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.3109/08977199709021510     Document Type: Article

References (28)

1. Bodine, D. M., Crosier, F. S. and Clark, S. C. (1991) Effects of hematopoietic growth factors on the survival of primitive stem cells in liquid suspension culture. Blood 78, 914-920.
2. Cumano, A., Dorshkind, K., Gillism S. and Paige, C. J. (1990) The influence of S17 stromal cells and interleukin 7 on B cell development. Eur. J. Immunol. 20, 2183-2189.
3. Cumano, A., Paige, C. J., Iscove, N. N. and Brady, G. (1992) Bipotential precursors of B cells and macrophages in murine fetal liver. Nature 356, 612-615.
4. Fleming, W. H., Alpern, E. J., Uchida, N., Ikuta, K., Spangrude, G. J. and Weissman, I. L. (1993) Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells. J. Cell. Biol. 122, 897-902.
5. Harris, J. F., Hawley, R. G., Hawley, T. S. and Crawford-Sharpe, G. C. (1992) Increased frequency of both total and specific monoclonal antibody producing hybridomas using a fusion partner that constitutively expresses recombinant IL-6. J. Immunol. Methods 148, 199-207.
6. Harrison, D. E. and Lerner, C. P. (1991) Most primitive hematopoietic stem cells are stimulated to cycle rapidly after treatment with 5-fluorouracil. Blood 78, 1237-1240.
7. Iscove, N. N., Shaw, A. R. and Keller, G. (1989) Net increase of pluripotent hematopoietic precursors in suspension culture in response to IL-1 and IL-3. J. Immunol. 142, 2332-2337.
8. Iscove, N. N. and Van, X. Q. (1990) Precursors (pre-CFCmulti) of multilineage hemopoietic colony-forming cells quantitated in vitro. Uniqueness of IL-1 requirement, partial separation from pluripotential colony-forming cells, and correlation with long term reconstituting cells in vivo. J. Immunol. 145, 190-195.
9. Jordan, C. T., McKearn, J. P. and Lemischka, I. R. (1990) Cellular and developmental properties of fetal hematopoietic stem cells. Cell 61, 953-963.
10. Jönsson, J.-I. and Phillips, R. A. (1993) lnterleukin-7 responsivencss of B220 + B-cell precursors from bone marrow decreases in aging mice. Cell. Immunol. 147, 267-278.
11. Karasuyama, H. and Melchers, F. (1988) Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol. 18, 97.
12. Knobel, K. M., McNally, M. A., Berson, A. E., Rood, D., Chen, K., Kilinski, L., Tran, K., Okarma, T. B. and Lebkowski, J. S. (1994) Long-term reconstitution of mice after ex vivo expansion of bone marrow cells: differential activity of cultured bone marrow and enriched stem cell populations. Exp. Hematol. 22, 1227-1235.
13. Lowry, P. A., Deacon, D., Whitefield, P., McGrath, H. E. and Quesenberry, P. J. (1992) Stem cell factor induction of in vitro murine hematopoietic colony formation by "subliminal" cytokine combinations: the role of "anchor factors". Blood 80, 663-669.
14. McKearn, J. P., McCubrey, J. and Fagg, B. (1985) Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors. Proc. Natl Acad. Sci. USA 82, 7414-7418.
15. Moore, M. A. S. (1992) Does stem cell exhaustion result from combining hematopoietic growth factors with chemotherapy? If so, how do we prevent it? Blood 80, 3-7.
16. Muench, M. O., Firpo, M. T. and Moore, M. A. (1993) Bone marrow transplantation with interleukin-1 plus kit-ligand ex vivo expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell lineage and proliferative potential. Blood 81, 3463-3473.
17. Muench, M. O., Schneider, J. G. and Moore, M. A. (1992) Interactions among colony-stimulating factors, IL-1 beta. IL-6, and kit- ligand in the regulation of primitive murine hematopoietic cells. Exp. Hematol. 20, 339-349.
18. Musashi, M., Clark, S. C., Sudo, T., Urdal, D. L. and Ogawa, M. (1991) Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice. Blood 78, 1448-1451.
19. Neben, S., Donaldson, D., Sieff, C., Mauch, P., Bodine, D., Ferrara, J., Yetz-Aldape, J. and Turner, K. (1994) Synergistic effects of interleukin-11 with other growth factors on the expansion of murine hematopoietic progenitors and maintenance of stem cells in liquid culture. Exp. Hematol. 22.
20. Ogawa, M. (1993) Differentiation and proliferation of hematopoietic stem cells. Blood 81, 2844-2853.
21. Ogawa, M., Matsuzaki, Y., Nishikawa, S., Hayashi, S., Kunisada, T., Sudo, T., Kina,T., Nakauchi, H. and Nishikawa, S. (1991) Expression and function of c-kit in hemopoietic progenitor cells. J. Exp. Med. 174, 63-71.
22. Okada, S., Nakauchi, H., Nagayoshi, K., Nishikawa, S., Nishikawa, S., Miura, Y. and Suda, T. (1991) Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule. Blood 78, 1706-1712.
23. Peters, S. O., Kittler, E. L., Ramshaw, H. S. and Quesenberry, P. J. (1995) Murine marrow cells expanded in culture with IL-3, IL-6, IL-11, and SCF acquire an engraftment defect in normal hosts. Exp. Hematol. 23, 461-469.
24. Peters, S. O., Kittler, E. L., Ramshaw, H. S. and Quesenberry, P. J. (1996) Ex vivo expansion of murine marrow cells with interleukin-3 (IL-3), IL-6, IL-11, and stem cell factor leads to impaired engraftment in irradiated hosts. Blood 87, 30-37.
25. Petzer, A. L., Hogge, D. E., Lansdorp, P. M., Reid, D. S. and Eaves, C. J. (1996) Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium. Proc: Natl Acad. Sci. USA 93, 1470-1474.
26. Schibler, K. R., Yang, Y.-C. and Christensen, R. D. (1992) Effect of interleukin-11 on cycling status and clonogenic maturation of fetal and adult hematopoietic progenitors. Blood 80, 900-903.
27. Spivak, J. L., Smith, R. R. L. and Ihle, J. N. (1985) Interleukin 3 promotes the in vitro proliferation of murine pluripotent hematopoietic stem cells. J. Clin. Invest. 76, 1613-1621.
28. Tsuji, K., Lyman, S. D., Sudo, T., Clark, S. C. and Ogawa, M. (1992) Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Blood 79, 2855-2860.