Rats with decreased brain cholecystokinin levels show increased responsiveness to peripheral electrical stimulation-induced analgesia

Brain Research

Volumn 745, Issue 1-2, 1997, Pages 158-164

  Zhang, Li Xin ^a,b   Li, Xiu Li ^a   Wang, Li ^a   Han, Ji Sheng ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Acupuncture; CCK 8; Cholecystokinin octapeptide; Neuropeptide; Opioid; Seizure

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; CHOLECYSTOKININ; CHOLECYSTOKININ OCTAPEPTIDE; NALTREXONE;

ACUPUNCTURE; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; FEMALE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MUTANT; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SEIZURE; SUBCUTANEOUS DRUG ADMINISTRATION; TAIL FLICK TEST;

ACOUSTIC STIMULATION; ACUPUNCTURE ANALGESIA; ANIMALS; BRAIN CHEMISTRY; CHOLECYSTOKININ; ELECTRIC STIMULATION; FEMALE; MALE; PAIN MEASUREMENT; PERIPHERAL NERVES; RADIOIMMUNOASSAY; RATS; RATS, INBRED STRAINS; RATS, WISTAR; SEIZURES;

EID: 0342601423     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01095-5     Document Type: Article

References (35)

1. Baber, N.S., Dourish, C.T. and Hill, D.R., The role of CCK, caerulein, and CCK antagonist in nociception, Pain, 39 (1989) 307-328.
2. Benfield, M.C. and Palkovits, M., Distribution of cholecystokinin (CCK) in the rat lower brain stem nuclei, Brain Res., 238 (1982) 260-265.
3. Chen, X.H., Han, J.S. and Huang, L.T., CCK receptor antagonist L-365,260 potentiated electroacupuncture analgesia in Wistar rats but not in audiogenic epileptic rats, Chin. Med. J. (Engl.), 107 (1994) 113-118.
4. Douris, C.T., Hawley, D. and Iversen, S.D., Enhancement of morphine analgesia and prevention of morphine tolerance in the rat by the cholecystokinin antagonist L-364,718, Eur. J. Pharmacol., 147 (1988) 469-472.
5. Dourish, C.T., O'Neill, M.F., Coughan, J., Kitchener, S.J., Hawley, D. and Iversen, S.D., The selective CCK-B antagonist L-365,260 enhances morphine analgesia and prevents morphine tolerance in rat, Eur. J. Pharmaciol., 175 (1990) 35-44.
6. Fan, S.G., Qu, Z.C., Zhe, Q.Z. and Han, J.S., GABA: antagonistic effect on electroacupuncture analgesia and morphine analgesia in the rat, Life Sci., 31 (1982) 1225-1228.
7. Paris, P.L., Komisaruk, B.R., Watkins, A.C. and Mayer, D., Evidence for the neuropeptide cholecystokinin as an antagonist of opiate analgesia, Science, 219 (1983) 310-312.
8. Han, J.S., The role of CCK in electro-acupuncture analgesia and electro-acupuncture tolerance. In C.T. Dounish, S.J. Cooper, S.D. Iversen and L.L. Iversen (Eds.), Multiple Cholecystokinin Receptors in the CNS, 1992, pp. 480-502.
9. Han, J.S., Chen, X.H., Sun, S.L., Xu, X.J., Yuan, Y., Yan, S.C., Hao, J.X. and Terenius, L., Effect of low- and high-frequency TENS on Met-enkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumbar CSF, Pain, 47 (1991) 295-298.
10. Han, J.S., Ding, X.Z. and Fan, S.G., Cholecystokinin octapeptide (CCK-8): antagonism to electroacupuncture analgesia and a possible role in electroacupuncture tolerance, Pain, 27 (1986) 101-115.
11. Han, J.S., Tang, J., Ren, M.F., Zhou, Z.F., Fan, S.G. and Qiu, X.C., Central neurotransmitters and acupuncture analgesia, Am. J. Chin. Med., 8 (1980) 331-348.
12. Han, J.S., Xie, G.X., Ding, X.Z. and Fan, S.G., High and low frequency electroacupuncture analgesia are mediated by different opioid peptides, Pain Suppl., 2 (1984) 543.
13. Hill, D.R., Shaw, T.M. and Woodruff, G.N., Binding sites for I-cholecystokinin in primate spinal cord are of the CCK-A subclass, Neurosci. Lett., 89 (1988) 286-289.
14. Itoh, S., Katsuura, G. and Maeda, Y., Caerulein and cholecystokinin suppress β-endorphin-induced analgesia in the rat, Eur. J. Pharmacol., 80 (1982) 421-425.
15. Kellstein, D.E. and Mayer, D.J., Spinal co-administration of cholecystokinin antagonists with morphine prevents the development of opioid tolerance, Pain, 47 (1991) 221-229.
16. Kellstein, D.E. and Mayer, D.J., Chronic administration of cholecystokinin antagonists reverses the enhancement of spinal morphine analgesia induced by acute pretreatment, Brain Res., 516 (1990) 263-270.
17. Noble, F., Derrien, M. and Roques, B.P., Modulation of opioid antinociception by CCK at the supraspinal level: evidence of regulatory mechanisms between CCK and enkephalin systems in the control of pain, Br. J. Pharmacol., 109 (1993) 1064-1070.
18. O'Neill, M.F., Dourish, C.T. and Iversen, S.D., Morphine analgesia in the rat paw pressure test is blocked by CCK and enhanced by the CCK antagonist MK-329, Neuropharmacology, 28 (1989) 243-248.
19. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1982.
20. Ren, M.F. and Han, J.S., Rat tail flick acupuncture analgesia model, Chin. J. Med., 92 (1979) 576-582.
21. Saito, A., Sankaran, H., Goldfine, J.D. and Williams, J.A., Cholecystokinin receptors in the brain: characterization and distribution, Science, 208 (1980) 1155-1156.
22. Stengaad-Pedersen, K. and Larsson, L.-I., Localization and opiate receptor binding of enkephalin, CCK and ACTH/beta-endorphin in the rat central nervous system, Peptides, Suppl., 1 (1981) 3-19.
23. Tseng, L.F. and Huang, F.Y., Release of immunoreactive [Met5]enkephalin and cholecystokinin from the spinal cord by beta-endorphin administered intraventricularly in the pentobarbital-anesthetized rat, Eur. J. Pharmacol., 215 (1992) 309-312.
24. Van Dijk, A., Richards, J.G., Trzeciak, A., Gillessen, D. and Mohler, H., Cholecystokinin receptors: biochemical demonstration and autoradiographical localization in rat brain and pancreas using H-cholecystokinin as radioligand, J. Neurosci., 4 (1984) 1021-1033.
25. Wang, Q., Mao, L.M. and Han, J.S., Diencephalon as a cardinal neural structure for mediating 2 Hz- but not 100 Hz-electroacupucture-induced tail flick reflex suppression, Behav. Brain. Res., 37 (1990) 149-156.
26. Watkins, L.R., Kinscheck, I.B. and Mayer, D.J., Potentiation of opioate analgesia and apparent reversal of morphine tolerance by proglumide, Science, 224 (1984) 395-396.
27. Wiesenfeld-Hallin, Z., Xu, X.J., Hughes, J., Horwell, D.C. and Hokfelt, T., PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analgesic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive reflexes, Proc. Natl. Acad. Sci. USA, 87 (1990) 7105-7109.
28. Woodruff, G.N. and Hughes, J., Cholecystokinin antagonists, Annu. Rev. Pharmacol. Toxicol., 31 (1991) 469-501.
29. Xu, W., Qiu, X.C. and Han, J.S., Serotonin receptor subtypes in spinal antinociception in the rat, J. Pharmacol. Exp. Ther., 269 (1994) 1182-1189.
30. Yamamoto, Y., Itano, T., Miyamoto, O., Tokuda, M., Matsui, H., Janjua, N.A., Suwaki, H., Okada, Y., Negi, T. and Murakami, T.H., Effect of ceruletide on epileptogenesis in amygdaloid kindled rats, Brain Res., 1993 (1993) 353-356.
31. Zetler, G., Anticonvulsant effects of caerulei, cholecystokinin octapeptide compared with those of diazepam, Eur. J. Pharmacol., 65 (1980) 297-300.
32. Zhang, L.X., Wu, M. and Han, J.S., Suppression of audiogenic epileptic seizures by intracerebral injection of a CCK gene vector, NeuroReport, 3 (1992) 700-702.
33. Zhang, L.X., Zhou, Y., Du, Y. and Han, J.S., Effect of CCK-8 on audiogenic epileptic seizures in P77PMC rats, Neuropeptides, 25 (1993) 73-76.
34. Zhao, D., Wu, X.R., Pei, Y.Q. and Zhao, Q.H., Long-term effect of febrile convulsion on seizure susceptibility in P77PMC rat resistant to acoustic stimuli but susceptible to kainate-induced seizure, Exp. Neurol., 88 (1985) 688-695.
35. Zhou, Y., Sun, Y.H., Shen, J.M. and Han, J.S., Increased release of immunoreactive CCK-7 by electroacupuncture and enhancement of electroacupuncture analgesia by CCK-B antagonist in rat spinal cord, Neuropeptides, 24 (1993) 139-144.