The influence of antagonists of poly(ADP-ribose) metabolism on acetaminophen hepatotoxicity

General Pharmacology

Volumn 27, Issue 1, 1996, Pages 167-170

  Kröger, Hans ^a,c   Ehrlich, Wilhelm ^b   Klewer, Monika ^b   Grätz, Regina ^b   Dietrich, Annette ^b   Miesel, Ralf ^a  

^a German Rheumatology Research Center   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

^c DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

Author keywords

Acetaminophen; Hepatotoxicity; Mice; Poly(ADP ribose)

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BENZAMIDE; CAFFEINE; LIVER PROTECTIVE AGENT; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARACETAMOL; POLY(ADENOSINE DIPHOSPHATE RIBOSE); THEOPHYLLINE; THYMIDINE; TRYPTOPHAN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME RELEASE; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

EID: 0342526809     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-3623(94)00293-2     Document Type: Article

References (25)

1. Althaus F. R., Lawrence S. D., He Y. Z., Sattler G. L., Tsukada Y. and Pitot H. C. (1982) Effects of altered (ADP-ribose) metabolism on expression of fetal functions by adult hepatocytes. Nature 300, 366-368.
2. Bergmeyer H. U. (1974) Methoden der enzymatischen Analyse I (Edited by Bergmeyer H. U.), p. 491. Verlag Chemie, Weinheim.
3. Blobel G. and Potter V. R. (1966) Nuclei from rat liver: isolation method that combines purity with high yield. Science 154, 1662-1665.
4. Borek C., Morgan W. F., Ong A. and Clever J. E. (1984) Inhibition of malignant transformation in vitro by inhibitors of poly(ADP-ribose) synthesis. Proc. Natl. Acad. Sci. USA 81, 243-247.
5. Boyer T. D. and Rouff S. L. (1971) Acetaminophen-induced hepatic necrosis and renal failure. J. Am. Med. Assoc. 218, 440-441.
6. Cerutti P. A. (1985) Prooxidant states and tumor promotion. Science 227, 375-381.
7. Davidson D. G. D. and Eastham W. N. (1966) Acute liver necrosis following overdose of paracetamol. Brit. Med. J. 2, 497-499.
8. Flower R. J., Moncada S. and Vane J. R. (1985) Drug therapy of inflammation: analgesic-antipyretics and anti-inflammatory agents. In. Goodman-Gilman's The Pharmacological Basis of Therapeutics (Edited by Goodman-Gilman A., Goodman L. S., Rall T. W. and Murad F.), pp. 692-695. Macmillan, New York.
9. Forth W., Henschler D., and Rummel W. (1983) Allgemeine und spezielle Pharmakologie und Toxikologie, pp. 1-85. B. I. Wissenschaftsverlag, Mannheim.
10. Halliwell B. and Gutteridge J. M. C. (1989) Protection against oxidants in biological systems: the superoxide theory of oxygen toxicity. In Free Radicals in Biology and Medicine II (Edited by Halliwell B. and Gutteridge J. M. C.), pp. 86-187. Clarendon, Oxford.
11. Hoshino J., Beckmann G. and Kroger H. (1993) 3-Aminobenzamide protects the mouse thymocytes in vitro from dexamethasone-medicated apoptotic cell death and cytolysis without changing DNA strand breakage. J. Steroid. Mol. Biol. 44, 113-119.
12. Jollow D. J., Thorgeirsson S.S., Potter W. Z., Hashimoto M. and Mitchell J. R. (1974) Acetaminophen-induced hepatic necrosis. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacol. 12, 251-271.
13. Kidwell W. R. and Burdette K. E. (1974) Poly(ADP-ribose) synthesis and cell division. Biochem. Biophys. Res. Commun. 61, 766-773.
14. Kröger H., Sohst S., Grätz R., Dietrich A. and Grahn H. (1989) Short time action of antirheumatic substances on the liver of rat. Protective effect of tryptophan + methionine. Gen. Pharmacol. 20, 211-212.
15. Lönn U. and Lönn S. (1985) Accumulation of 10-kilobase DNA replication intermediates in cells treated with 3-amino-benzamide. Proc. Natl. Acad. Sci. USA 82, 104-108.
16. Ludwig J. and Axelsen R. (1983) Drug effects on the liver. An updated tabular compilation of drugs and drug-related hepatic diseases. Digest. Dis. Sci. 28, 651-666.
17. Meredith T. J., Vale J. A. and Goulding R. (1981) The epidemiology of acute acetaminophen poisoning in England and Wales. Arch. Intern. Med. 141, 397-400.
18. Miesel R. and Zuber M. (1993) Copper-dependent antioxidase defenses in inflammatory and autoimmune rheumatic diseases. Inflammation 17, 283-294.
19. Murphy M. P. and Brand M. D. (1987) The control of electron flux through cytochrome oxidase. Biochem. J. 243, 499-505.
20. Nduka N., Skidmore C. J. and Shall S. (1980) The enhancement of cytotoxicity of N-methyl-N-nitrosourea and of gamma-radiation by inhibitors of poly-(ADP-ribose) polymerase. Eur. J. Biochem. 105, 525-530.
21. Oikawa A., Tohda H., Kanai M., Miwa M., and Sugimura T. (1980) Inhibitors of poly(adenosine diphosphate ribose) polymerase induce sister chromatid exchanges. Biochem. Biophys. Res. Commun. 97, 1311-1316.
22. Peters M., Meyer zum Büschenfelde K. H. and Gerken G. (1993) Acute hepatic failure: limitations of medical treatment and indications for liver transplantation. Clin. Investig. 71, 875-881.
23. Seeff L. B., Cuccherini B. A., Zimmerman H. J., Adler E. and Benjamin S. B. (1986) Acetaminophen hepatotoxicity in alcoholics: a therapeutic misadventure. Ann. Intern. Med. 104, 399-404.
24. Shall S. (1983) ADP-ribosylation, DNA repair, cell differentiation, and cancer. In ADP-Ribosylation, DNA Repair and Cancer (Edited by Miwa M., Hayaishi O., Shall S., Smulson M. and Sugimura T.), p. 5. Jap. Sci. Sos. Press, Tokyo/VNU Science Press, Utrecht.
25. Volans G. N. (1976) Self-poisoning and suicide due to paracetamol. J. Int. Med. Res. 4, 7-13.