A putative latency promoter/enhancer (P(LAT2)) region of pseudorabies virus contains a virulence determinant

Journal of General Virology

Volumn 81, Issue 2, 2000, Pages 415-420

  Boldogköi, Zsolt ^a   Erdélyi, Ferenc ^a   Fodor, István ^a,b  

^a SZENT ISTVÁN UNIVERSITY   (Hungary)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ENHANCER REGION; GENE DELETION; PRIORITY JOURNAL; PROMOTER REGION; PSEUDORABIES HERPETOVIRUS; VIRUS LATENCY; VIRUS MUTANT; VIRUS VIRULENCE;

DNA VIRUSES; HERPETOVIRUS; RNA VIRUSES; SUID HERPESVIRUS 1;

EID: 0342470946     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-81-2-415     Document Type: Article

References (19)

1. Banfield, B. W., Yap, G. S., Knapp, A. C. & Enquist, L. W. (1998). A chicken embryo eye model for the analysis of alphaherpesvirus neuronal spread and virulence. Journal of Virology 72, 4580-4588.
2. Boldogköi, Z. & Murvai, J. (1994). A novel explanation for the existence of open reading frames on the latency-associated transcripts of alphaherpesviruses. Virus Genes 9, 47-51.
3. Boldogköi, Z., Murvai, J. & Fodor, I. (1995). G and C accumulation at silent positions of codons produces additional ORFs. Trends in Genetics 11, 125-126.
4. Boldogköi, Z., Braun, A., Antal, J. & Fodor, I. (1998a). A restriction cleavage and transfection system for introducing foreign DNA sequences into the unique and inverted repeat regions of a herpesvirus. Research in Virology 149, 87-97.
5. Boldogköi, Z., Braun, A., Medveczky, I., Glávits, R., Gyúró, B. & Fodor, I. (1998b). Analysis of the equalization of inverted repeats and neurovirulence using a pseudorabies virus mutant strain altered at the Ul/Ir junction. Virus Genes 17, 89-98.
6. Card, J. P., Whealy, M. E., Robbins, A. K. & Enquist, L. W. (1992). Pseudorabies virus envelope glycoprotein gl influences both neurotropism and virulence during infection of the rat visual system. Journal of Virology 66, 3032-3041.
7. Card, J. P., Enquist, L. W., Miller, A. D. & Yates, B. J. (1997). Differential tropism of pseudorabies virus for sensory neurons in the cat. Journal of Neurovirology 3, 49-61.
8. Cheung, A. K. (1991). Cloning of the latency gene and the early protein O gene of pseudorabies virus. Journal of Virology 65, 5260-5271.
9. R junction reduces pseudorabies neurovirulence. Journal of Virology 69, 1334-1338.
10. Dean, H. J., Miller, J. M., Ackerman, M. R., Gao, X. Y., Anderson, L. L., Jacobson, C. D. & Cheung, A. K. (1996). Replication and pathogenicity after intranasal and intracranial inoculation of swine with recombinant pseudorabies virus containing a deletion at the UL/IR junction. Virology 223, 19-28.
11. Elhai, J. & Wolk, C. P. (1988). A versatile class of positive-selection vectors based on the non-viability of palindrome containing plasmids, that allows cloning into the polylinkers. Gene 68, 119-138.
12. Field, H. J. & Hill, T. J. (1975). The pathogenesis of pseudorabies in mice: virus replication at the inoculation site and axonal uptake. Journal of General Virology 26, 145-148.
13. Kaplan, A. S. & Watter, A. E. (1959). A comparison of herpes simplex and pseudorabies virus. Virology 7, 394-407.
14. Lomniczi, B., Watanabe, S., Ben-Porat, T. & Kaplan, A. S. (1984). Genetic basis of neurovirulence of pseudorabies virus. Journal of Virology 52, 198-205.
15. Rall, G. F., Kupershmidt, S., Sugg, N., Veach, R. A. & Ben-Porat, T. (1992). Functions of the sequences at the end of inverted repeats of pseudorabies virus. Journal of Virology 66, 1506-1519.
16. Reed, L. J. & Muench, M. (1938). A simple method of estimating fifty percent end points. American Journal of Hygiene 27, 493-497.
17. Ryan, P. & Shankly, F. L. (1996). A double-strand break in a herpesvirus genome stimulates targeted homologous recombination with exogenous, cloned viral sequences. Journal of Virological Methods 57, 95-107.
18. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
19. Vlcek, C., Kozmik, Z., Paces, V., Schirm, S. & Schwyzer, M. (1993). Pseudorabies virus immediate early gene overlaps with an oppositely oriented open reading frame - characterization of their promoter and enhancer regions. Virology 179, 365-377.