Physical properties and tissue distribution of adriamycin encapsulated in polyethyleneglycol-coated liposomes

Advanced Drug Delivery Reviews

Volumn 24, Issue 2-3, 1997, Pages 257-263

  Sadzuka, Yasuyuki ^a   Hirota, Sadao ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

adriamycin; aqueous layer thickness; liposome; polyethyleneglycol; prolonged circulation; reticuloendothelial system; zeta potential

Indexed keywords

DRUG DOSAGE; DRUG INTERACTIONS; DRUG THERAPY; ELECTRIC PROPERTIES; ENCAPSULATION; IONIC STRENGTH; LIPIDS; PHARMACOKINETICS; PHYSICAL PROPERTIES; POLYETHYLENE GLYCOLS; TISSUE;

ADRIAMYCIN; BIOACTIVITY; BIODISTRIBUTION; DEBYE HUCKEL PARAMETER; LIPOSOMALIZATION; LIPOSOMES; PROLONGED CIRCULATION; RETICULOENDOTHELIAL SYSTEM; ZETA POTENTIAL;

DRUG PRODUCTS;

1 MONOMETHOXYPOLYETHYLENE GLYCOL 2,3 DIMYRISTOYLGLYCEROL; BUFFER; CHOLESTEROL; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DIMYRISTOYLPHOSPHATIDYLGLYCEROL; DOXORUBICIN; LACTIC ACID; LIPOSOME; MACROGOL; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; CIRCULATION TIME; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG TISSUE LEVEL; EHRLICH ASCITES TUMOR; ENCAPSULATION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; IONIC STRENGTH; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RETICULOENDOTHELIAL SYSTEM; TISSUE DISTRIBUTION; ZETA POTENTIAL;

EID: 0342460488     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(96)00466-8     Document Type: Conference Paper

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