Characterization of the active site thiol group of rhinovirus 2A proteinase

FEBS Letters

Volumn 481, Issue 3, 2000, Pages 289-292

  Sarkany Z ^a   Skern, T ^b   Polgar L ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Active site reactivity; Cysteine protease; Kinetic deuterium isotope effect; Picornain 2A; Rhinovirus protease

Indexed keywords

CYSTEINE PROTEINASE; DEUTERIUM; IMIDAZOLE DERIVATIVE; IODOACETAMIDE; IODOACETIC ACID; PAPAIN; PICORNAIN 2A; THIOL GROUP; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN RHINOVIRUS; NONHUMAN; PH; PRIORITY JOURNAL;

BINDING SITES; CATALYSIS; CYSTEINE ENDOPEPTIDASES; DEUTERIUM OXIDE; DITHIONITROBENZOIC ACID; ENZYME ACTIVATION; HUMAN; HYDROGEN-ION CONCENTRATION; KINETICS; OLIGOPEPTIDES; OXIDATION-REDUCTION; RHINOVIRUS; SUBSTRATE SPECIFICITY; SULFHYDRYL COMPOUNDS; SULFHYDRYL REAGENTS; SUPPORT, NON-U.S. GOV'T; TITRIMETRY;

EID: 0342409311     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(00)02024-X     Document Type: Article

References (25)

1. Krausslich H.-G., Wimmer E. Ann. Rev. Biochem. 57:1988;701-754.
2. Skern T., Liebig H.-D. Methods Enzymol. 244:1994;583-595.
3. Ryan M.D., Flint M. J. Gen. Virol. 78:1997;699-723.
4. Bergmann, E.M. and James, M.N.G. (1999) in: Proteases of Infectious Agents (Dunn, B.M., Ed.), pp. 139-163, Academic Press, London.
5. Allaire M., Cherney M.M., Malcolm A., James M.N.G. Nature (Lond.). 369:1994;72-76.
6. Matthews D.A., Smith W.W., Ferre R.A., Condon B., Budahazi G., Sisson W., Villafranca J.E., Janson C.A., McElroy H.E., Gribskov C.L., Worland S. Cell. 77:1994;761-771.
7. Mosimann S.C., Cherney M.M., Sia S., Plotch S., James M.N.G. J. Mol. Biol. 273:1997;1032-1047.
8. Petersen J.F.W., Cherney M.M., Liebig H.-D., Skern T., Kuechler E., James M.N.G. EMBO J. 18:1999;5463-5475.
9. Voss T., Meyer R., Sommergruber W. Protein Sci. 4:1995;2526-2531.
10. Sommergruber W., Zorn M., Blaas D., Fessl F., Volkmann P., Maurer-Fogy I., Pallai P., Merluzzi V., Matteo M., Skern T., Kuechler E. Virology. 169:1989;68-77.
11. Polgár L. FEBS Lett. 47:1974;15-18.
12. Luderer-Gmach M., Liebig H.-D., Sommergruber W., Voss T., Fessl F., Skern T., Kuechler E. Biochem. J. 318:1996;213-218.
13. Ellman G.L. Arch. Biochem. Biophys. 82:1959;70-77.
14. Liebig H.-D., Ziegler E., Yan R., Hartmuth K., Klump H., Kowalski H., Blaas D., Sommergruber W., Frasel L., Lamphear B., Rhoads R., Kuechler E., Skern T. Biochemistry. 32:1993;7581-7588.
15. Leatherbarrow, R.J. (1998) GraFit, Version 4, Erythacus Software Ltd., Staines.
16. Glasoe P.K., Long F.A. J. Phys. Chem. 64:1960;188-190.
17. Polgár L. Eur. J. Biochem. 98:1979;369-374.
18. Brocklehurst K., Kowlessur D., Patel G., Templeton W., Quigley K., Thomas E.W., Wharton C.W., Willenbrock F., Szawelski R.J. Biochem. J. 250:1988;761-772.
19. Wandinger A., Creighton D.J. FEBS Lett. 116:1980;116-121.
20. Polgár L. Eur. J. Biochem. 33:1973;104-109.
21. Halász P., Polgár L. Eur. J. Biochem. 79:1977;491-494.
22. Polgár L. FEBS Lett. 38:1974;187-190.
23. Csoma C., Polgár L. Biochem. J. 222:1984;769-776.
24. Kembhavi A.A., Buttle D.J., Rauber P., Barrett A.J. FEBS Lett. 283:1991;277-280.
25. Chen J.-M., Rawlings N.D., Stevens R.A.E., Barrett A.J. FEBS Lett. 441:1998;361-365.