Olfactory functions in Parkinson's disease and Alzheimer's disease

Chemical Senses

Volumn 22, Issue 1, 1997, Pages 105-110

  Lehrner, J P ^a   Brucke T ^a   Dal Bianco, P ^a   Gatterer, G ^b   Kryspin Exner, I ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b Geriatric Center Wienerwald   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MEMORY; OLFACTORY DISCRIMINATION; PARKINSON DISEASE; PRIORITY JOURNAL; SMELLING;

AGED; ALZHEIMER DISEASE; FEMALE; HUMANS; MALE; MIDDLE AGED; ODORS; OLFACTORY NERVE; PARKINSON DISEASE; SENSORY THRESHOLDS; SMELL;

EID: 0342276105     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/22.1.105     Document Type: Article

References (50)

1. Ansari, K.A. and Johnson, A. (1975) Olfactory functions in patients with Parkinson disease. J. Chronic Dis., 28, 493-497.
2. Averback, P. (1983) Two new lesions in Alzheimer's disease. Lancet, ii, 1203-1204
3. Braak, H. and Braak, E. (1991) Neuropathological staging of Alzheimer-related changes. Acta Neuropathol., 82, 239-259.
4. Braak, H., Braak, E., Yilmazer, D., de Vos, R., Jansen, E., Bohl, E. and Jellinger, K. (1994) Amygdala pathology in Parkinson's disease. Acta Neuropathol., 88, 493-500.
5. Braak, H., Braak, E., Yilmazer, D., Schultz, C., De Vos, R.A.I, and Jansen, E.N.H. (1995) Nigral and extranigral pathology in Parkinson's disease. J. Neural Transm., 46(Suppl.), 15-31.
6. Burns, R.S., Chiueh, C.C., Markey, S.P., Ebert, M.H., Jacobowitz, D.M. and Kopin, I.J. (1983) A primate model of Parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. Natl Acad. Sci. USA, 80, 4546-4550.
7. Corwin, J., Serby, M., Conrad, P. and Rotrosen, J. (1985) Olfactory recognition deficit in Alzheimer's and Parkinsonian dementias. IRCS Med. Sci., 13, 260.
8. Crino, P.D., Martin, J.A., Hill, W.D., Greenberg, B., Lee, V.M. and Trojanowsky, J.Q. (1995) β-Amyloid peptide and amyloid precurser proteins in olfactory mucosa of patients with Alzheimer's disease, Parkinson's disease, and Down syndrome. Ann. Otol. Rhinol. Laryngol., 104, 655-661.
9. Daniel, S.E. and Hawkes, C.H. (1992) Preliminary diagnosis of Parkinson's disease by olfactory bulb pathology. Lancet, 340, 186.
10. Delacourte, A. (1994) Pathological tau proteins of Alzheimer's disease as a biochemical marker of neurofibrillary degeneration. Biomed. Pharmacother., 48, 287-295.
11. Doty, R.L. (1991) Olfactory dysfunction in neurodegenerative disorders. In Getchell, T.V., Doty, R.L., Bartoshuk, L.M. and Snow, J.B. (eds), Smell and Taste in Health and Disease. Raven, New York, pp. 735-751.
12. Doty, R.L., Reyes, P.F. and Gregor, G. (1987) Presence of both odor identification and detection deficits in Alzheimer's disease. Brain Res. Bull., 18, 597-600.
13. Doty, R.L., Deems., D.A. and Stellar, S. (1988) Olfactory dysfunction in Parkinsonism: a general deficit unrelated to neurologic signs, disease stage, or disease duration. Neurology, 38, 1237-1244.
14. Doty, R.L., Riklan, M., Deems, D.A., Reynolds, C. and Stellar, S. (1989) The olfactory deficits of Parkinson's disease: evidence for independence. Ann. Neurol., 25, 251-261.
15. Doty, R.L., Perl, D.P., Steele, J.C., Chen, K.M., Pierce, J.D., Reyes, P. and Kurland, L.T. (1991) Odor identification deficit of the Parkinsonism-dementia complex of Guam: equivalence to that of Alzheimer's and idiopathic Parkinson's disease. Neurology, 41 (suppl. 2), 77-80.
16. Doty, R.L., Stern, M.B., Pfeiffer, C., Golomp, S.M. and Hurtig, H.I. (1992a) Bilateral olfactory dysfunction in early stage treated and untreated idiopathic Parkinson's disease. J. Neurol. Neurosurg. Psychiat., 55, 138-142.
17. Doty, R.L., Singh, A., Tetrud, J. and Langston, J.W. (1992b) Lack of major olfactory dysfunction in MPTP-induced Parkinsonism. Ann. Neurol., 32, 97-100.
18. Doty, R.L., McKeown, D.A., Lee, W.W. and Shaman, P. (1995) A study of test-retest reliability of ten olfactory tests. Chem. Senses, 20, 645-565.
19. Esiri, M.M and Wilcock, G. (1984) The olfactory bulbs in Alzheimer's disease. J. Neurol. Neurosurg. Psychiat., 47, 56-60.
20. Flower, K.A., Pearce, I. and Pearce, J.M.S. (1984) Recognition memory in Parkinson's disease. J. Neurol. Neurosurg. Psychiat., 47, 1174-1181.
21. Hyman, B.T., Arriagada, P.V. and Van Hoesen, G.W. (1991) Pathologic changes in the olfactory system in aging and Alzheimer's disease. Ann. NY Acad. Sci., 640, 14-19.
22. Kesslak, J. P., Cotman, C.W., Chui, H.I., Van den Noort, S., Fang, H., Pfeffer, R. and Lynch, G. (1988) Olfactory tests as possible probes for detecting and monitoring Alzheimer's Disease. Neurobiol. Aging, 9, 399-403.
23. Knupfer, L. and Spiegel, R. (1986) Differences in olfactory test performance between normal aged, Alzheimer and vascular type dementia individuals. Int. J. Geriat. Psychiat., 1, 3-14.
24. Koss, E. (1986) Olfactory dysfunction in Alzheimer's disease. Dev. Neuropsychol., 2, 89-99.
25. Koss, E., Weiffenbach, J.M., Haxby, V., Friedland, R.P. (1987) Olfactory detection and recognition in Alzheimer's disease. Lancet, i, 622.
26. Koss, E., Weiffenbach, J.M., Haxby, J.V., Friedland, R.P. (1988) Olfactory detection and identification performance are dissociate in early Alzheimer's disease. Neurology, 38, 1228-1232.
27. Laak, H.J.T., Renkawek, K., Workum, F.P.A. (1994) The olfactory bulb in Alzheimer's disease: a morphologic study of neuron loss, tangles and senile plaques in relation to olfaction. Alzheim. Dis. Assoc. Disord., 8, 38-48.
28. Lehrner, J.P. (1993a) Olfactory functioning from childhood to old age. Chem. Senses, 18, 587 (abstract).
29. Lehrner, J.P. (1993b) Gender differences in long-term odor recognition memory: verbal versus sensory influences and the consistency of label use. Chem. Senses, 18, 17-26.
30. Lehrner, J.P., Brücke, T., Kryspin-Exner, I., Asenbaum, S. and Podreka, I. (1995a) Impaired olfactory function in Parkinson's disease. Lancet, 345, 1054-1055.
31. Lehrner, J.P., Kryspin-Exner, I. and Vetter, N. (1995b) Higher olfactory threshold and decreased odor identification ability in HIV-infected persons. Chem. Senses, 20, 325-328.
32. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. and Stranlan, E. M. (1984) Clinical diagnosis of Alzheimer's disease. Neurology, 34, 939-944
33. Moberg, P.J., Pearlson, G.D., Speedie, L.J., Lipsey, J.R., Strauss, M.E. and Folstein, S.E. (1987) Olfactory recognition: differential impairments in early and late Huntington's and Alzheimer's diseases. J. Clin. Exp. Neuropsychol., 9, 650-664.
34. Ohm, T.G. and Braak, H. (1987) Olfactory bulb changes in Alzheimer's disease. Acta Neuropathol., 73, 365-369.
35. Pearce, R.K.B., Hawkes, C.H. and Daniel, S.E. (1995) The anterior olfactory nucleus in Parkinson's disease. Move. Disord., 10, 283-287.
36. Pearson, R.C.A., Esiri, M.M., Hiorns, R.W., Wilcock, G.K. and Powell, T.P.S. (1985) Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer's disease. Proc. Natl Acad. Sci. USA, 82, 4531-4534.
37. Pollack, N. and Norman, D. (1964) A non-parametric analysis of recognition experiments. Psychon. Sci., 1, 125-126.
38. Price, J.L. (1990) Olfactory system. In Paxinos, G. (ed.), The Human Nervous System. Academic Press, New York, pp. 979-998.
39. Quinn, N.P, Rossor, M. and Marsden, C.D. (1987) Olfactory thresholds in Parkinson's disease. J. Neurol. Neurosurg. Psychiat., 50, 88-89.
40. Reyes, P.F., Deems, D.A. and Suarez, M.G. (1993) Olfactory-related changes in Alzheimer's disease: a quantitative neuropathologic study. Brain Res. Bull., 32, 1-5.
41. Rezek, D.L. (1987) Olfactory deficits as a neurologic sign in dementia of the Alzheimer type. Arch. Neurol., 44, 1030-1032.
42. Serby, M., Larson, P. and Kalkstein, D. (1991) The nature and course of olfactory deficits in Alzheimer's disease. Am. J. Psychiat., 148, 357-360.
43. Stern, M.B., Doty, R.L., Corcoran, P., Crawford, D., McKeown, D.A., Adler, C., Golomp, S. and Hurtig, H. (1994) Olfactory function in Parkinson's disease subtypes. Neurology, 44, 266-268.
44. Tabaton, M., Cammarata, S., Mancardi, G.L., Cordone, G., Perry, G. and Loeb, C. (1991) Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease. Neurology, 41, 391-394.
45. Talamo, B.R., Rudel, R.A., Kosik, K.S., Lee, V., Neff, S., Adelman, L. and Kauer, J.S. (1989) Pathological changes in olfactory neurons in patients wih Alzheimer's disease. Nature, 337, 736-739.
46. Trojanowski, J.Q., Newman, P.D., Hill, W.D. and Lee, V. (1991) Human olfactory epithelium in normal aging, Alzheimer's disease, and other neurodegenerative disorders. J. Comp. Neurol., 310, 365-376.
47. Ward, C.D., Hess, W.A. and Calne, D.B. (1983) Olfactory impairment in Parkinson's disease. Neurology, 33, 943-946.
48. Warner, M.D., Peabody, C.A., Flattery, J.J. and Tinklenberg, J.R. (1986) Olfactory deficits and Alzheimer's disease. Biol. Psychiat., 21, 116-118.
49. Wenning, G.K., Shepard, B., Hawkes, C., Petruckevitch, A., Lees, A. and Quinn, N. (1995) Olfactory function in atypical Parkinsonian syndromes. Acta Neurol. Scand., 91, 247-250.
50. Yamagishi, M., Ishizuka, Y. and Seki, K. (1994) Pathology of olfactory mucosa in patients with Alzheimer's disease. Ann. Otol. Rhinol. Laryngol., 103, 421-427.