Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings

Organic Letters

Volumn 5, Issue 21, 2003, Pages 3783-3786

  Nelson, Alshakim ^a   Stoddart, J Fraser ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLODEXTRIN; CYCLODEXTRIN DERIVATIVE; LACTOSE; LECTIN; POLYMER;

ARTICLE; CHEMICAL PROCEDURES; HYDROPHOBICITY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; SYNTHESIS;

CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CYCLODEXTRINS; GLYCOSIDES; LECTINS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; POLYMERS; THERMODYNAMICS;

EID: 0242712912     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0353464     Document Type: Article

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63. Although the CDs are often assumed to adopt a head-to-head/tail-to-tail co-conformation along the polymer chain, a recent study has shown that the ratio of the formation of head-to-head versus head-to-tail co-conformations is 2:1. See: Miyake, K.; Yasuda, S.; Harada, A.; Sumaoka, J.; Komiyama, M.; Shigekawa, H. J. Am. Chem. Soc. 2003, 125, 5080-5085. The graphical representation shown in the abstract of this communication is an idealized one since we have no experimental data to allow us to be specific about co-conformational arrangements.