1,5-Isoquinolinediol increases the frequency of gene targeting by homologous recombination in mouse fibroblasts

Biochemistry and Cell Biology

Volumn 81, Issue 1, 2003, Pages 17-24

  Semionov, Alexandre ^a   Cournoyer, Denis ^b   Chow, Terry Y K ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

DNA recombination; Gene targeting; PARP inhibition

Indexed keywords

ALCOHOLS; CELLS; DNA; GENES; ORGANIC POLYMERS;

MOUSE FIBROBLASTS;

BIOCHEMISTRY;

1,5 ISOQUINOLINEDIOL; 3 METHOXYBENZAMIDE; BENZAMIDE DERIVATIVE; ENZYME INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLASMID DNA; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DNA RECOMBINATION; ENZYME INHIBITION; FIBROBLAST CULTURE; GENE MUTATION; GENE TARGETING; GENE THERAPY; GENETIC TRANSFECTION; GENOME; HERPES SIMPLEX VIRUS; MOUSE; NONHUMAN; TARGET CELL;

ANIMALS; CELL LINE; CELL SURVIVAL; ENZYME INHIBITORS; FIBROBLASTS; GENE TARGETING; MICE; PLASMIDS; POLY(ADP-RIBOSE) POLYMERASES; QUINOLINES; RECOMBINATION, GENETIC;

ANIMALIA; HERPES; MAMMALIA; SIMPLEXVIRUS;

EID: 0242684603     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o02-172     Document Type: Article

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