Isolation, excystation and axenization of Giardia lamblia isolates: In vitro susceptibility to metronidazole and albendazole

Journal of Antimicrobial Chemotherapy

Volumn 51, Issue 4, 2003, Pages 1017-1020

  Cruz, Agostinho ^a,b   Sousa, M Isaura ^b   Azeredo, Zaida ^b   Leite, Emilia ^a   de Sousa, J C Figueiredo ^b   Cabral, Miguel ^b  

^a Escola Superior de Tecnologia da Saude do Porto   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Albendazole; Giardia; Metronidazole; Susceptibility assays

Indexed keywords

ALBENDAZOLE; ANTIPARASITIC AGENT; METRONIDAZOLE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CELL ADHESION; CONTROLLED STUDY; CULTURE MEDIUM; FECES ANALYSIS; GIARDIA LAMBLIA; HUMAN; IC 50; IN VITRO STUDY; NONHUMAN; PARASITE CULTIVATION; PARASITE ISOLATION; TROPHOZOITE;

ALBENDAZOLE; ANIMALS; ANTIPROTOZOAL AGENTS; CELL ADHESION; FECES; GIARDIA LAMBLIA; GIARDIASIS; METRONIDAZOLE; PORTUGAL;

EID: 0242684595     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkg150     Document Type: Article

References (10)

1. Adam, R. D. (2001). Biology of Giardia lamblia. Clinical Microbiology Reviews 55, 706-32.
2. Schupp, D., Januschka, M., Sherlock, L., Stibbs, H., Meyer, E., Bemrick, W. et al. (1988). Production of viable Giardia cysts in vitro: determination by fluorogenic dye staining, excystation, and animal infectivity in the mouse and Mongolian gerbil. Gastroenterology 95, 1-10.
3. Farbey, M. D., Reynoldson, J. A. & Thompson, R. C. A. (1995). In vitro drug susceptibility of 29 isolates of Giardia duodenalis from humans as assessed by an adhesion assay. International Journal for Parasitology 25, 593-9.
4. Hautus, M., Kortbeek, L., Vetter, J. & Laarman, J. (1988). In vitro excystation and subsequent axenic growth of Giardia lamblia. Transactions of The Royal Society of Tropical Medicine and Hygiene 82, 858-61.
5. Romero-Cabello, R., Robert, L., Munoz-Garcia, R. & Tanaka, J. (1995). Randomized study comparing the safety and efficacy of albendazole and metronidazole in the treatment of giardiasis in children. Revista Latinoamericana de Microbiologia 37, 315-23.
6. Meloni, B. P., Thompson, R. C. A., Reynoldson, J. & Seville P. (1990). Albendazole, a more effective antigiardial agent in vitro than metronidazole or tinidazole. Transactions of The Royal Society of Tropical Medicine and Hygiene 84, 375-9.
7. Nash, T. E., Ohl, C. A., Thomas, E., Subramanian, G., Keiser, P. & Moore, T. A. (2001). Treatment of patients with refractory giardiasis. Clinical Infectious Diseases 33, 22-8.
8. Meloni, B. P. & Thompson, R. C. A. (1987). Comparative studies on the axenic in vitro cultivation of Giardia of human and canine origin: evidence for intraspecific variation. Transactions of The Royal Society of Tropical Medicine and Hygiene 81, 637-40.
9. Cedillo-Rivera, R. & Muñoz, O. (1992). In-vitro susceptibility of Giardia lamblia to albendazole, mebendazole and other chemotherapeutic agents. Journal of Medical Microbiology 37, 221-4.
10. Townson, S. M., Laqua, H., Upcroft, P., Boreham, P. F. & Upcroft, J. A. (1992). Induction of metronidazole and furazolidone resistance in Giardia. Transactions of The Royal Society of Tropical Medicine and Hygiene 86, 521-2.