Role of the Electrogenic Na/K Pump in Disinhibition-Induced Bursting in Cultured Spinal Networks

Journal of Neurophysiology

Volumn 90, Issue 5, 2003, Pages 3119-3129

  Darbon, P ^a   Tscherter, A ^a   Yvon, C ^a   Streit, J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); POTASSIUM; STROPHANTHIDIN;

ANIMAL TISSUE; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; HYPERPOLARIZATION; INTERNEURON; MEMBRANE DEPOLARIZATION; NERVE CELL CULTURE; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE; SPINAL CORD; SPINAL NERVE; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; ANIMALS; BICUCULLINE; CELLS, CULTURED; NA(+)-K(+)-EXCHANGING ATPASE; NEURAL INHIBITION; ORGAN CULTURE TECHNIQUES; RATS; SPINAL CORD; STROPHANTHIDIN;

EID: 0242677530     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00579.2003     Document Type: Article

References (41)

1. Ballerini L, Bracci E, and Nistri A. Pharmacological block of th electrogenic sodium pump disrupts rhythmic bursting induced by strychnine and bicuculline in the neonatal rat spinal cord. J Neurophysiol 77: 17-23, 1997.
2. Ballerini L and Galante M. Network bursting by organotypic spinal slice cultures in the presence of bicuculline and/or strychnine is developmentally regulated. Eur J Neurosci 10: 2871-2879, 1998.
3. Ballerini L, Galante M, Grandolfo M, and Nistri A. Generation of rhythmic patterns of activity by ventral interneurones in rat organotypic spinal slice culture. J Physiol 517: 459-475, 1999.
4. Ballion B, Morin D, and Viala D. Forelimb locomotor generators and quadrupedal locomotion in the neonatal rat. Eur J Neurosci 14: 1727-1738, 2001.
5. Bracci E, Ballerini L, and Nistri A. Spontaneous rhythmic bursts induced by pharmacological block of inhibition in lumbar motoneurons of the neonatal rat spinal cord. J Neurophysiol 75: 640-647. 1996.
6. Braschler UF, Iannone A, Spenger C, Streit J, and Lüscher H-R. A modified roller tube technique for organotypic cocultures of embryonic ra spinal cord, sensory ganglia and skeletal muscle. J Neurosci Methods 29 121-129, 1989.
7. Cazalets JR, Borde M, and Clarac F. The synaptic drive from the spina locomotor network to motoneurons in the newborn rat. J Neurosci 16 298-306, 1996.
8. Cazalets JR, Grillner P, Menard I, Cremieux J, and Clarac F. Two type of motor rhythm induced by NMDA and amines in an in vitro spinal cord preparation of neonatal rat. Neurosci Lett 111: 116-121, 1990.
9. Cowley KC and Schmidt BJ. Effects of inhibitory amino acid antagonists on reciprocal inhibitory interactions during rhythmic motor activity in the in vitro neonatal rat spinal cord. J Neurophysiol 74: 1109-1117, 1995.
10. Darbon P, Pignier C, Niggli E, and Streit J. Involvement of calcium in rhythmic activity induced by disinhibition in cultured spinal cord networks J Neurophysiol 88: 1461-1468, 2002a.
11. Darbon P, Scicluna L, Tscherter A, and Streit J. Mechanisms controlling bursting activity induced by disinhibition in spinal cord networks. Eur J Neurosci 15: 671-683, 2002b.
12. del Negro CA, Hsiao CF, and Chandler SH. Outward currents influencing bursting dynamics in guinea pig trigeminal motoneurons. J Neurophysiol 81: 1478-1485, 1999.
13. Demir R, Gao BX, Jackson MB, and Ziskind-Conhaim L. Interaction between multiple rhythm generators produce complex patterns of oscillation in the developing rat spinal cord. J Neurophysiol 87: 1094-1105, 2002.
14. + pump in rat dorsal root ganglia neurons. Neuroscience 93: 723-729, 1999.
15. el Manira A, Tegner J, and Grillner S. Calcium-dependent potassiun channels play a critical role for burst termination in the locomotor network in lamprey. J Neurophysiol 72: 1852-1861, 1994.
16. + current and slow cumulative spike adaptation in mouse and guinea-pig neocortical neurones in slices. J Physiol 493: 83-97, 1996.
17. Grillner S, Parker D, and el Manira A. Vertebrate locomotion: a lamprey perspective. Ann NY Acad Sci 860: 1-18, 1998.
18. Hamill OP, Marty A, Neher E, Sakmann B, and Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pfluegers Arch 391: 85-100, 1981.
19. Hanson MG and Landmesser LT. Characterization of the circuits tha generate spontaneous episodes of activity in the early embryonic mouse spinal cord. J Neurosci 23: 587-600, 2003.
20. Kiehn O and Kjaerulff O. Distribution of central pattern generators for rhythmic motor outputs in the spinal cord of limbed vertebrates. Ann NY Acad Sci 860: 110-129, 1998.
21. Kudo N and Yamada T. N-Methyl-D,L-aspartate-induced locomotor activity in a spinal cord-hindlimb muscles preparation of the newborn rat studied in vitro. Neurosci Lett 75: 43-48, 1987.
22. Latham PE, Richmond BJ, Nelson PG, and Nirenberg S. Intrinsic dynamics in neuronal networks. I. Theory. J Neurophysiol 83: 808-827, 2000.
23. Lauger P. Current noise generated by electrogenic ion pumps. Eur Biophys J 117-128, 1984.
24. Muller W and Swandulla D. Synaptic feedback excitation has hypothalamic neural networks generate quasirhythmic burst activity. J Neurophysiol 73: 855-861, 1995.
25. Munakata M, Fujimoto M, Jin YH, and Akaike N. Characterization of electrogenic Na/K pump in rat neostriatal neurons. Brain Res 800: 282-293, 1998.
26. O'Donovan MJ and Rinzel J. Synaptic depression: a dynamic regulator of synaptic communication with varied functional roles. Trends Neurosci 20: 431-433, 1997.
27. Powers RK, Sawczuk A, Musick JR, and Binder MD. Multiple mechanisms of spike-frequency adaptation in motoneurones. J Physiol Paris 93: 101-114, 1999.
28. Ross ST and Soltesz I. Selective depolarization of interneurons in the early posttraumatic dentate gyrus: involvement of the Na(+)/K(+)-ATPase. J Neurophysiol 83: 2916-2930, 2000.
29. Rozzo A, Ballerini L, Abbate G, and Nistri A. Experimental and modeling studies of novel bursts induced by blocking Na(+) pump and synaptic inhibition in the rat spinal cord. J Neurophysiol 88: 676-691, 2002.
30. Sanchez-Vives MV and McCormick DA. Cellular and network mechanisms of rhythmic recurrent activity in neocortex. Nat Neurosci 3: 1027-1034, 2000.
31. Senatorov VV, Mooney D, and Hu B. The electrogenic effects of Na(+)-K(+)-ATPase in rat auditory thalamus. J Physiol 502: 375-385, 1997.
32. Shen KZ and Johnson SW. Sodium pump evokes high density pump current in rat midbrain dopamine neurons. J Physiol 512: 449-457, 1998.
33. Staley KJ, Longacher M, Bains JS, and Yee A. Presynaptic modulation of CA3 network activity. Nat Neurosci 1: 201-209, 1998.
34. Streit J. Regular oscillations of synaptic networks in vitro. J Neurophysiol 70: 871-878, 1993.
35. Streit J, Tscherter A, Heuschkel MO, and Renaud P. The generation of rhythmic activity in dissociated cultures of rat spinal cord. Eur J Neurosci 14: 191-202, 2001.
36. Tabak J, Rinzel J, and O'Donovan MJ. The role of activity-dependent network depression in the expression and self-regulation of spontaneous activity in the developing spinal cord. J Neurosci 21: 8966-8978, 2001.
37. Thompson SM and Prince DA. Activation of electrogenic sodium pump in hippocampal CA1 neurons following glutamate-induced deplarization. J Neurophysiol 56: 507-522, 1986.
38. + channels. J Neurosci 18: 1893-1903, 1998.
39. Tsai MC and Chen YH. Bursting firing of action potentials in central snail neurons elicited by d-amphetamine: role of the electrogenic sodium pump. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 111: 131-141, 1995.
40. Tscherter A, Heuschkel MO, Renaud P, and Streit J. Spatiotemporal characterization of rhythmic activity in rat spinal cord slice cultures. Eur J Neurosci 14: 179-190, 2001.
41. Wenner P and O'Donovan MJ. Mechanisms that initiate spontaneous network activity in the developing chick spinal cord. J Neurophysiol 86: 1481-1498, 2001.