메뉴 건너뛰기




Volumn 90, Issue 5, 2003, Pages 3155-3160

PI3-Kinase Inhibitors Abolish the Enhanced Chronotropic Effects of Angiotensin II in Spontaneously Hypertensive Rat Brain Neurons

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 2 MORPHOLINO 8 PHENYLCHROMONE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; CALPHOSTIN C; LOSARTAN; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN KINASE C; WORTMANNIN;

EID: 0242677526     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00222.2003     Document Type: Article
Times cited : (15)

References (35)
  • 1
    • 0033956392 scopus 로고    scopus 로고
    • Angiotensin peptides and baroreflex control of sympathetic outflow: Pathways and mechanisms of the medulla oblongata
    • Averill DB and Diz DI. Angiotensin peptides and baroreflex control of sympathetic outflow: pathways and mechanisms of the medulla oblongata. Brain Res Bull 51: 119-128, 2000.
    • (2000) Brain Res Bull , vol.51 , pp. 119-128
    • Averill, D.B.1    Diz, D.I.2
  • 2
    • 0030772513 scopus 로고    scopus 로고
    • IGF-I modulates N and L calcium channels in a PI3-kinase-dependent manner
    • Blair LA and Marshall J. IGF-I modulates N and L calcium channels in a PI3-kinase-dependent manner. Neuron 19: 421-429, 1997.
    • (1997) Neuron , vol.19 , pp. 421-429
    • Blair, L.A.1    Marshall, J.2
  • 4
    • 0033824138 scopus 로고    scopus 로고
    • International union of pharmacology. XXIII. The angiotensin II receptors
    • de Gasparo M, Catt KJ, Inagami T, Wright JW, and Unger T. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 52: 415-472, 2000.
    • (2000) Pharmacol Rev , vol.52 , pp. 415-472
    • De Gasparo, M.1    Catt, K.J.2    Inagami, T.3    Wright, J.W.4    Unger, T.5
  • 5
    • 0036090823 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: An emerging therapeutic target
    • Eldar-Finkelman H. Glycogen synthase kinase 3: an emerging therapeutic target. Trends Mol Med 8: 126-132, 2002.
    • (2002) Trends Mol Med , vol.8 , pp. 126-132
    • Eldar-Finkelman, H.1
  • 6
    • 0035134144 scopus 로고    scopus 로고
    • Hormonal and neurotransmitter roles for angiotensin in the regulation of central autonomic function
    • Ferguson AV, Washburn DL, and Latchford KJ. Hormonal and neurotransmitter roles for angiotensin in the regulation of central autonomic function. Exp Biol Med 226: 85-96, 2001.
    • (2001) Exp Biol Med , vol.226 , pp. 85-96
    • Ferguson, A.V.1    Washburn, D.L.2    Latchford, K.J.3
  • 7
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes center stage more than 20 years after its discovery
    • Frame S and Cohen P. GSK3 takes center stage more than 20 years after its discovery. Biochem J 359: 1-16, 2001.
    • (2001) Biochem J , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 8
    • 0022873434 scopus 로고
    • Quantitative autoradiography of angiotensin II receptors in the SHR brain
    • Gehlert DR, Speth RC, and Wamsley JK. Quantitative autoradiography of angiotensin II receptors in the SHR brain. Peptides 7: 1021-1027, 1986.
    • (1986) Peptides , vol.7 , pp. 1021-1027
    • Gehlert, D.R.1    Speth, R.C.2    Wamsley, J.K.3
  • 9
    • 0023835384 scopus 로고
    • Increased concentration of angiotensin II binding sites in selected brain areas of spontaneously hypertensive rats
    • Gutkind JS, Kurihara M, Castren E, and Saavedra JM. Increased concentration of angiotensin II binding sites in selected brain areas of spontaneously hypertensive rats. J Hypertens. 6: 79-84, 1988.
    • (1988) J Hypertens , vol.6 , pp. 79-84
    • Gutkind, J.S.1    Kurihara, M.2    Castren, E.3    Saavedra, J.M.4
  • 10
    • 0031853171 scopus 로고    scopus 로고
    • Hypothalamic angiotensin receptor subtypes in normotensive and hypertensive rats
    • Han NL and Sim MK. Hypothalamic angiotensin receptor subtypes in normotensive and hypertensive rats. Am J Physiol Heart Circ 275: H703-709, 1998.
    • (1998) Am J Physiol Heart Circ , vol.275
    • Han, N.L.1    Sim, M.K.2
  • 11
    • 0030575636 scopus 로고    scopus 로고
    • Complex activation of inducble transcription factors in the brain of normotensive and spontaneously hypertensive rats following central angiotensin II administration
    • Lebrun CJ, Blume A, Herdegen T, Mollenhoff E, and Unger T. Complex activation of inducble transcription factors in the brain of normotensive and spontaneously hypertensive rats following central angiotensin II administration. Regul Pept 66:19-23, 1996.
    • (1996) Regul Pept , vol.66 , pp. 19-23
    • Lebrun, C.J.1    Blume, A.2    Herdegen, T.3    Mollenhoff, E.4    Unger, T.5
  • 12
    • 0028796839 scopus 로고
    • Neuronal excitation by angiotensin II in the rostral ventrolateral medulla of the rat in vitro
    • Li YW and Guyenet PG. Neuronal excitation by angiotensin II in the rostral ventrolateral medulla of the rat in vitro. Am J Physiol Regulatory Integrative Comp Physiol 268: R272-277, 1995.
    • (1995) Am J Physiol Regulatory Integrative Comp Physiol , vol.268
    • Li, Y.W.1    Guyenet, P.G.2
  • 13
    • 0028292393 scopus 로고
    • Regulation of angiotensin II type 1 receptor mRNA in neuronal cultures of normotensive and spontaneously hypertensive rat brains by phorbol esters and forskolin
    • Lu D, Sumners C, and Raizada MK. Regulation of angiotensin II type 1 receptor mRNA in neuronal cultures of normotensive and spontaneously hypertensive rat brains by phorbol esters and forskolin. J Neurochem 62: 2079-2084, 1994.
    • (1994) J Neurochem , vol.62 , pp. 2079-2084
    • Lu, D.1    Sumners, C.2    Raizada, M.K.3
  • 14
    • 0032514215 scopus 로고    scopus 로고
    • Regulation of anigotensin II-induced neuromodulation by MARCKS in brain neurons
    • Lu D, Yang H, Lenox RH, and Raizada MK. Regulation of anigotensin II-induced neuromodulation by MARCKS in brain neurons. J Cell Biol 142: 217-227, 1998.
    • (1998) J Cell Biol , vol.142 , pp. 217-227
    • Lu, D.1    Yang, H.2    Lenox, R.H.3    Raizada, M.K.4
  • 18
    • 0037163065 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of deoxycorticosterone acetate-salt hypertensive rats
    • Northcott CA, Poy MN, Najjar SM, and Watts SW. Phosphoinositide 3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of deoxycorticosterone acetate-salt hypertensive rats. Circ Res 91: 360-369, 2002.
    • (2002) Circ Res , vol.91 , pp. 360-369
    • Northcott, C.A.1    Poy, M.N.2    Najjar, S.M.3    Watts, S.W.4
  • 20
    • 0035281015 scopus 로고    scopus 로고
    • Adenoviral vector demonstrates that angiotensin II-induced depression of the cardiac baroreflex is mediated by endothelial nitric oxide synthase in the nucleus tractus solitarii of the rat
    • Paton JF, Deuchars J, Ahmad Z, Wong LF, Murphy D, and Kasparov S. Adenoviral vector demonstrates that angiotensin II-induced depression of the cardiac baroreflex is mediated by endothelial nitric oxide synthase in the nucleus tractus solitarii of the rat. J Physiol 531: 445-458, 2001.
    • (2001) J Physiol , vol.531 , pp. 445-458
    • Paton, J.F.1    Deuchars, J.2    Ahmad, Z.3    Wong, L.F.4    Murphy, D.5    Kasparov, S.6
  • 22
    • 0035726046 scopus 로고    scopus 로고
    • Differential role of kinases in brain stem of hypertensive and normotensive rats
    • Seyedabadi M, Goodehild AK, and Pilowsky PM. Differential role of kinases in brain stem of hypertensive and normotensive rats. Hypertension 38: 1087-1092, 2001.
    • (2001) Hypertension , vol.38 , pp. 1087-1092
    • Seyedabadi, M.1    Goodehild, A.K.2    Pilowsky, P.M.3
  • 25
    • 0025320646 scopus 로고
    • Physiological and pharmacological comparisons of angiotensin II receptors in neuronal and astrocyte glial cultures
    • Sumners C, Myers LM, Kalberg CJ, and Raizada MK. Physiological and pharmacological comparisons of angiotensin II receptors in neuronal and astrocyte glial cultures. Prog Neurobiol 34: 355-385, 1990.
    • (1990) Prog Neurobiol , vol.34 , pp. 355-385
    • Sumners, C.1    Myers, L.M.2    Kalberg, C.J.3    Raizada, M.K.4
  • 26
    • 0025887310 scopus 로고
    • Angiotensin II receptor subtypes coupled with distinct signal transduction mechanism on neurons and astrocytes from rat brain
    • Sumners C, Tang W, Zelezna B, and Raizada MK. Angiotensin II receptor subtypes coupled with distinct signal transduction mechanism on neurons and astrocytes from rat brain. Proc Natl Acad Sci USA 88: 7567-7571, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7567-7571
    • Sumners, C.1    Tang, W.2    Zelezna, B.3    Raizada, M.K.4
  • 27
    • 0036175502 scopus 로고    scopus 로고
    • Chronotropic action of angiotensin II in Neurons via protein kinase C and CaMKII
    • Sun CW, Sumners C, and Raizada MK. Chronotropic action of angiotensin II in Neurons via protein kinase C and CaMKII. Hypertension 39: 562-566, 2002.
    • (2002) Hypertension , vol.39 , pp. 562-566
    • Sun, C.W.1    Sumners, C.2    Raizada, M.K.3
  • 28
    • 0033555721 scopus 로고    scopus 로고
    • PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor
    • Takeda H, Matozaki T, Takada T, Noguchi T, Yamao T, Tsuda M, Ochi F, Fukunaga K, Inagaki K, and Kasuga M. PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor. EMBO J 18: 386-395, 1999.
    • (1999) EMBO J , vol.18 , pp. 386-395
    • Takeda, H.1    Matozaki, T.2    Takada, T.3    Noguchi, T.4    Yamao, T.5    Tsuda, M.6    Ochi, F.7    Fukunaga, K.8    Inagaki, K.9    Kasuga, M.10
  • 29
    • 0030805669 scopus 로고    scopus 로고
    • Mechanisms underlying the chronotropic effect of angiotensin II on cultured neurons from rat hypothalamus and brain stem
    • Wang DS, Gelband CH, Sumners C, and Posner P. Mechanisms underlying the chronotropic effect of angiotensin II on cultured neurons from rat hypothalamus and brain stem. J Neurophysiol 78: 1013-1020, 1997.
    • (1997) J Neurophysiol , vol.78 , pp. 1013-1020
    • Wang, D.S.1    Gelband, C.H.2    Sumners, C.3    Posner, P.4
  • 31
    • 0029897648 scopus 로고    scopus 로고
    • Regulation of neuromodulatory actions of angiotensin II in the brain neurons by the Ras-dependent mitogen-activated protein kinase pathway
    • Yang H, Lu D, Yu K, and Raizada MK. Regulation of neuromodulatory actions of angiotensin II in the brain neurons by the Ras-dependent mitogen-activated protein kinase pathway. J Neurosci 16: 4047-4058, 1996.
    • (1996) J Neurosci , vol.16 , pp. 4047-4058
    • Yang, H.1    Lu, D.2    Yu, K.3    Raizada, M.K.4
  • 32
    • 0033119104 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat
    • Yang H and Raizada MK. Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat. J Neurosci 19: 2413-2423, 1999.
    • (1999) J Neurosci , vol.19 , pp. 2413-2423
    • Yang, H.1    Raizada, M.K.2
  • 35
    • 0035021758 scopus 로고    scopus 로고
    • Chronotropic effect of angiotensin II via type 2 receptors in rat brain neurons
    • Zhu M, Sumners C, Gelband CH, and Posner P. Chronotropic effect of angiotensin II via type 2 receptors in rat brain neurons. J Neurophysiol 85: 2177-2183, 2001.
    • (2001) J Neurophysiol , vol.85 , pp. 2177-2183
    • Zhu, M.1    Sumners, C.2    Gelband, C.H.3    Posner, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.