Up-regulation of microtubule-associated protein 4 and drebrin A mRNA expression by antidepressants in rat hippocampus following chronic stress

Neuroscience Letters

Volumn 351, Issue 3, 2003, Pages 206-208

  Yang, Hong Ju ^a   Li, Yun Feng ^a   Zhang, Hang Ting ^a   Zhang, Feng Qin ^a   Zhao, Nan ^a   Gong, Zheng Hua ^a   Luo, Zhi Pu ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Chronic stress; Desipramine; Differential display; Drebrin A; Fluoxetine; Microtubule associated protein 4

Indexed keywords

ANTIDEPRESSANT AGENT; COMPLEMENTARY DNA; DESIPRAMINE; DREBRIN; FLUOXETINE; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL DISPLAY; DOT HYBRIDIZATION; DRUG ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; HIPPOCAMPUS; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRESS; UPREGULATION;

EID: 0242667907     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2003.08.006     Document Type: Article

References (17)

1. Bassam B.J., Caetano-Anolles G., Gresshoff P.M. Fast and sensitive silver staining of DNA in polyacrylamide gels. Anal. Biochem. 196:1991;80-83.
2. Dumans R.S., Malberg J., Thome J. Neural plasticity to stress and antidepressant treatment. Biol. Psychiatry. 46:1999;1181-1191.
3. Eriksson E. Antidepressant drugs: does it matter if they inhibit the reuptake of noradrenaline or serotonin? Acta Psychiatr. Scand. 101:(Suppl. 402):2000;12-17.
4. Harigaya Y., Shoji M., Shirao T., Hirai S. Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease. J. Neurosci. Res. 43:1996;87-92.
5. Harrison P.J. The neuropathology of primary mood disorder. Brain. 125:2002;1428-1449.
6. Hayashi K., Shirao T. Change in the shape of dendritic spines caused by overexpression of drebrin in cultured cortical neurons. J. Neurosci. 19:1999;3918-3925.
7. Liang P., Pardee A.B. Differential display and cloning of messenger RNAs from human breast cancer versus mammary epithelial cells. Cancer Res. 52:1992;6966-6968.
8. Miguel-Hidalgo J.J., Rajkowska G. Morphological brain changes in depression: can antidepressants reverse them? CNC Drugs. 16:2002;361-372.
9. Molina V.A., Volosin M., Cancela L., Keller E., Murua V.S., Basso A.M. Effect of chronic variable stress on monoamine receptors: influence of imipramine administration. Pharmacol. Biochem. Behav. 35:1990;335-340.
10. Norrholm S.D., Ouimet C.C. Altered dendritic spine density in animal models of depression and in response to antidepressant treatment. Synapse. 42:2001;151-163.
11. Pei Q., Burnet P.J., Zetterstrom T.S. Changes in mRNA abundance of microtubule-associated proteins in the rat brain following electroconvulsive shock. NeuroReport. 9:1998;391-394.
12. Perez J., Mori S., Caivano M., Popoli M., Zanardi R., Smeraldi E., Racagni G. Effect of fluoxamine on the protein phosphorylation system associated with rat neuronal microtubules. Eur. Neuropsychopharmacol. 5:(Suppl.):1995;65-69.
13. Perez J., Tinelli D., Brunello N. cAMP-dependent phosphorylation of soluble and crude microtubule fractions of rat cerebral cortex after prolonged desmethylimipramine treatment. Eur. J. Pharmacol. 172:1989;305-316.
14. Popoli M., Mori S., Brunello N., Gennarelli M., Racagni G. Serine/threonine kinases as molecular targets of antidepressants: implications for pharmacological treatment and pathophysiology of affective disorders. Pharmacol. Ther. 899:2001;149-170.
15. Rajkowska G. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biol. Psychiatry. 48:2000;766-777.
16. Sanchez C., Diaz-Nido J., Avila J. Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of neuronal cytoskeleton function. Prog. Neurobiol. 61:2000;133-168.
17. Shim K.S., Lubec G. Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome. Neurosci. Lett. 324:2002;209-212.