메뉴 건너뛰기




Volumn 6, Issue 4, 2003, Pages 189-194

Effectiveness of Statin-Gemfibrozil Combination Therapy in Patients with Mixed Hyperlipidemia: Experience of a Community Lipid Clinic and Safety Review from the Literature

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FLUINDOSTATIN; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; PRAVASTATIN; SIMVASTATIN; TRIACYLGLYCEROL;

EID: 0242662536     PISSN: 1520037X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1520-037X.2003.02200.x     Document Type: Review
Times cited : (4)

References (42)
  • 1
    • 0035500039 scopus 로고    scopus 로고
    • AHA/ACC guidelines for preventing heart attack and death with atherosclerotic cardiovascular disease: 2001 Update
    • Smith SC Jr, Blair SN, Bonow RO, et al. AHA/ACC guidelines for preventing heart attack and death with atherosclerotic cardiovascular disease: 2001 update. J Am Coll Cardiol. 2001;38:1581-1583.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 1581-1583
    • Smith S.C., Jr.1    Blair, S.N.2    Bonow, R.O.3
  • 2
    • 0030882897 scopus 로고    scopus 로고
    • Safety and efficacy of long-term statin-fibrate combinations in patients with refractory familial combined hyperlipidemia
    • Athyros VG, Papageorgiou AA, Hatzikonstandinou HA, et al. Safety and efficacy of long-term statin-fibrate combinations in patients with refractory familial combined hyperlipidemia. Am J Cardiol. 1997;80:608-613.
    • (1997) Am J Cardiol , vol.80 , pp. 608-613
    • Athyros, V.G.1    Papageorgiou, A.A.2    Hatzikonstandinou, H.A.3
  • 3
    • 0032788490 scopus 로고    scopus 로고
    • Long-term safety and efficacy of combination gemfibrozil and HMG-CoA reductase inhibitors for the treatment of mixed lipid disorders
    • Murdock DK, Murdock AK, Murdock RW, et al. Long-term safety and efficacy of combination gemfibrozil and HMG-CoA reductase inhibitors for the treatment of mixed lipid disorders. Am Heart J. 1999;138:151-155.
    • (1999) Am Heart J , vol.138 , pp. 151-155
    • Murdock, D.K.1    Murdock, A.K.2    Murdock, R.W.3
  • 4
    • 0026513207 scopus 로고
    • Lovastatin-induced rhabdomyolysis in the absence of concomitant drugs
    • Wallace CS, Mueller BA. Lovastatin-induced rhabdomyolysis in the absence of concomitant drugs. Ann Pharmacother. 1992;26(2):190-192.
    • (1992) Ann Pharmacother , vol.26 , Issue.2 , pp. 190-192
    • Wallace, C.S.1    Mueller, B.A.2
  • 5
    • 0025934984 scopus 로고
    • Lovastatin-associated rhabdomyolysis
    • Sylvain-Moore H, Worden JP Jr. Lovastatin-associated rhabdomyolysis. Heart Lung. 1991;20(5 pt 1):464-466.
    • (1991) Heart Lung , vol.20 , Issue.5 PART 1 , pp. 464-466
    • Sylvain-Moore, H.1    Worden J.P., Jr.2
  • 6
    • 0030855706 scopus 로고    scopus 로고
    • Rhabdomyolysis, acute renal failure and hepatopathy induced by lovastatin monotherapy
    • Chu PH, Chen WJ, Chiang CW, et al. Rhabdomyolysis, acute renal failure and hepatopathy induced by lovastatin monotherapy. Jpn Heart J. 1997;38(4):541-545.
    • (1997) Jpn Heart J , vol.38 , Issue.4 , pp. 541-545
    • Chu, P.H.1    Chen, W.J.2    Chiang, C.W.3
  • 7
    • 0025613424 scopus 로고
    • Rhabdomyolysis secondary to lovastatin therapy
    • Manoukian AA, Bhagavan NV, Hayashi T, et al. Rhabdomyolysis secondary to lovastatin therapy. Clin Chem. 1990;36(12):2145-2147.
    • (1990) Clin Chem , vol.36 , Issue.12 , pp. 2145-2147
    • Manoukian, A.A.1    Bhagavan, N.V.2    Hayashi, T.3
  • 8
  • 9
    • 0026032967 scopus 로고
    • Rhabdomyolysis with simvastatin use
    • Berland Y, Vacher Coponat H, Durand C, et al. Rhabdomyolysis with simvastatin use. Nephron. 1991; 57(3):365-366.
    • (1991) Nephron , vol.57 , Issue.3 , pp. 365-366
    • Berland, Y.1    Vacher Coponat, H.2    Durand, C.3
  • 10
    • 0026672714 scopus 로고
    • Massive rhabdomyolysis and simvastatin
    • Bizzaro N, Bagolin E, Milani L, et al. Massive rhabdomyolysis and simvastatin. Clin Chem. 1992;38(8 pt 1):1504.
    • (1992) Clin Chem , vol.38 , Issue.8 PART 1 , pp. 1504
    • Bizzaro, N.1    Bagolin, E.2    Milani, L.3
  • 11
    • 0034046256 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors and myotoxicity
    • Ucar M, Mjorndal T, Dhalqvist R. HMG-CoA reductase inhibitors and myotoxicity. Drug Saf. 2000;22(6):441-457.
    • (2000) Drug Saf , vol.22 , Issue.6 , pp. 441-457
    • Ucar, M.1    Mjorndal, T.2    Dhalqvist, R.3
  • 13
    • 0025278247 scopus 로고
    • Lovastatin-induced acute rhabdomyolysis
    • Kogan AD, Orenstein S. Lovastatin-induced acute rhabdomyolysis. Postgrad Med J. 1990;66:294-296.
    • (1990) Postgrad Med J , vol.66 , pp. 294-296
    • Kogan, A.D.1    Orenstein, S.2
  • 14
    • 0029817859 scopus 로고    scopus 로고
    • Rhabdomyolysis and acute renal failure associated with gemfibrozil therapy
    • Gorriz JL, Sancho A, Lopez-Martin JM, et al. Rhabdomyolysis and acute renal failure associated with gemfibrozil therapy. Nephron. 1996;74(2):437-438.
    • (1996) Nephron , vol.74 , Issue.2 , pp. 437-438
    • Gorriz, J.L.1    Sancho, A.2    Lopez-Martin, J.M.3
  • 16
    • 0032005257 scopus 로고    scopus 로고
    • Rhabdomyolysis after taking atorvastatin with gemfibrizol
    • Duell PB, Connor WE, Illingworth DR. Rhabdomyolysis after taking atorvastatin with gemfibrizol. Am J Cardiol. 1998; 81(3):368-369.
    • (1998) Am J Cardiol , vol.81 , Issue.3 , pp. 368-369
    • Duell, P.B.1    Connor, W.E.2    Illingworth, D.R.3
  • 17
    • 0032940035 scopus 로고    scopus 로고
    • Rhabdomyolysis and renal failure associated with cerivastatin-gemfibrizol combination therapy
    • Pogson GW, Kindred LH, Carper BG. Rhabdomyolysis and renal failure associated with cerivastatin-gemfibrizol combination therapy. Am J Cardiol. 1999;83(7):1146.
    • (1999) Am J Cardiol , vol.83 , Issue.7 , pp. 1146
    • Pogson, G.W.1    Kindred, L.H.2    Carper, B.G.3
  • 18
    • 0034161582 scopus 로고    scopus 로고
    • Rhabdomyolysis in a patient receiving the combination of cerivastatin and gemfibrizol
    • Bermingham RP, Whitsitt TB, Smart ML, et al. Rhabdomyolysis in a patient receiving the combination of cerivastatin and gemfibrizol. Am J Health Syst Pharm. 2000;57(5):461-464.
    • (2000) Am J Health Syst Pharm , vol.57 , Issue.5 , pp. 461-464
    • Bermingham, R.P.1    Whitsitt, T.B.2    Smart, M.L.3
  • 19
    • 0034663113 scopus 로고    scopus 로고
    • Rhabdomyolysis due to combination therapy with cerivastatin and gemfibrizol
    • Alexandridis G, Pappas GA, Elisaf MS. Rhabdomyolysis due to combination therapy with cerivastatin and gemfibrizol. Am J Med. 2000;109 (3):261-262.
    • (2000) Am J Med , vol.109 , Issue.3 , pp. 261-262
    • Alexandridis, G.1    Pappas, G.A.2    Elisaf, M.S.3
  • 20
    • 0033900967 scopus 로고    scopus 로고
    • A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrizol combination therapy - A case report
    • Ozdemir O, Boran M, Gokce V, et al. A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrizol combination therapy-a case report. Angiology. 2000;51(8):695-697.
    • (2000) Angiology , vol.51 , Issue.8 , pp. 695-697
    • Ozdemir, O.1    Boran, M.2    Gokce, V.3
  • 21
    • 0025365041 scopus 로고
    • Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination
    • Pierce LR, Wysowski DK, Gross TP. Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination. JAMA. 1990;264(1):71-75.
    • (1990) JAMA , vol.264 , Issue.1 , pp. 71-75
    • Pierce, L.R.1    Wysowski, D.K.2    Gross, T.P.3
  • 22
    • 0025710768 scopus 로고
    • Myopathy and rhabdomyolysis with lovastatin taken with gemfibrozil
    • Goldstein MR. Myopathy and rhabdomyolysis with lovastatin taken with gemfibrozil. JAMA. 1990;264(23):2991-2992.
    • (1990) JAMA , vol.264 , Issue.23 , pp. 2991-2992
    • Goldstein, M.R.1
  • 23
    • 0028829562 scopus 로고
    • Pancreatitis and rhabdomyolysis associated with lovastatin-gemfibrozil therapy
    • Abdul-Ghaffar N, El-Sonbaty MR. Pancreatitis and rhabdomyolysis associated with lovastatin-gemfibrozil therapy. J Clin Gastroenterol. 1995;21(4):340-341.
    • (1995) J Clin Gastroenterol , vol.21 , Issue.4 , pp. 340-341
    • Abdul-Ghaffar, N.1    El-Sonbaty, M.R.2
  • 24
    • 0026636425 scopus 로고
    • Gemfibrozil-lovastatin therapy for primary hyperlipoproteinemias
    • Glueck CJ, Oakes N, Speirs J, et al. Gemfibrozil-lovastatin therapy for primary hyperlipoproteinemias. Am J Cardiol. 1992;70:1-9.
    • (1992) Am J Cardiol , vol.70 , pp. 1-9
    • Glueck, C.J.1    Oakes, N.2    Speirs, J.3
  • 25
    • 0025181465 scopus 로고
    • Rhabdomyolysis and acute renal failure induced by combination lovastatin and Gemfibrozil therapy
    • Marais GE, Larson KK. Rhabdomyolysis and acute renal failure induced by combination lovastatin and Gemfibrozil therapy. Ann Intern Med. 1990;112(3):228-230.
    • (1990) Ann Intern Med , vol.112 , Issue.3 , pp. 228-230
    • Marais, G.E.1    Larson, K.K.2
  • 26
    • 0030473211 scopus 로고    scopus 로고
    • Possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil
    • Van Puijenbroek EP, Du Buf-Vereijken PW, Spooren PF, et al. Possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil. J Intern Med. 1996; 240(6):403-404.
    • (1996) J Intern Med , vol.240 , Issue.6 , pp. 403-404
    • Van Puijenbroek, E.P.1    Du Buf-Vereijken, P.W.2    Spooren, P.F.3
  • 27
    • 0030921631 scopus 로고    scopus 로고
    • Rhabdomyolysis associated with simvastatin-gemfibrozil therapy
    • Tal A, Raieshhawari M, Isley W. Rhabdomyolysis associated with simvastatin-gemfibrozil therapy. South Med J. 1997; 90(5):546-547.
    • (1997) South Med J , vol.90 , Issue.5 , pp. 546-547
    • Tal, A.1    Raieshhawari, M.2    Isley, W.3
  • 28
    • 0024514075 scopus 로고
    • Influence of lovastatin plus gemfibrozil on plasma lipids and lipoproteins in patients with heterozygous familial hypercholesterolemia
    • Illingworth DR, Bacon S. Influence of lovastatin plus gemfibrozil on plasma lipids and lipoproteins in patients with heterozygous familial hypercholesterolemia. Circulation. 1989; 79:590-596.
    • (1989) Circulation , vol.79 , pp. 590-596
    • Illingworth, D.R.1    Bacon, S.2
  • 29
    • 0030954159 scopus 로고    scopus 로고
    • Long term treatment with pravastatin alone and in combination with gemfibrozil in familial type IIB hyperlipoproteinemia or combined hyperlipidemia
    • Napoli C, Lepore S, Chiariello P, et al. Long term treatment with pravastatin alone and in combination with gemfibrozil in familial type IIB hyperlipoproteinemia or combined hyperlipidemia. J Cardiovasc Pharmacol Ther. 1997;2(1):17-26.
    • (1997) J Cardiovasc Pharmacol Ther , vol.2 , Issue.1 , pp. 17-26
    • Napoli, C.1    Lepore, S.2    Chiariello, P.3
  • 30
    • 0030268441 scopus 로고    scopus 로고
    • Effect of combination therapy with lipid-reducing drugs in patients with coronary heart disease and "normal" cholesterol levels. A randomized, placebo-controlled trial
    • Pasternak RC, Brown LE, Stone PH, et al., for the Harvard Atherosclerosis Reversibility Project (HARP) Study Group. Effect of combination therapy with lipid-reducing drugs in patients with coronary heart disease and "normal" cholesterol levels. A randomized, placebo-controlled trial. Ann Intern Med. 1996;125:529-540.
    • (1996) Ann Intern Med , vol.125 , pp. 529-540
    • Pasternak, R.C.1    Brown, L.E.2    Stone, P.H.3
  • 31
    • 0027400118 scopus 로고
    • Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia
    • Wiklund O, Bergman M, Bondjers G, et al. Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia. Am J Med. 1993;94(1):13-20.
    • (1993) Am J Med , vol.94 , Issue.1 , pp. 13-20
    • Wiklund, O.1    Bergman, M.2    Bondjers, G.3
  • 32
    • 0028033548 scopus 로고
    • Safety of combined pravastatin-gemfibrozil therapy
    • Rosenson RS, Frauenheim WA. Safety of combined pravastatin-gemfibrozil therapy. Am J Cardiol. 1994;74:499-500.
    • (1994) Am J Cardiol , vol.74 , pp. 499-500
    • Rosenson, R.S.1    Frauenheim, W.A.2
  • 33
    • 0029042641 scopus 로고
    • Pharmacokinetics of the combination of fluvastatin and gemfibrozil
    • Spence JD, Munoz CE, Hendricks L, et al. Pharmacokinetics of the combination of fluvastatin and gemfibrozil. Am J Cardiol. 1995;76:80A-83A.
    • (1995) Am J Cardiol , vol.76
    • Spence, J.D.1    Munoz, C.E.2    Hendricks, L.3
  • 34
    • 0023860312 scopus 로고
    • Rhabdomyolysis in patients receiving lovastatin after cardiac transplantation
    • Tobert JA. Rhabdomyolysis in patients receiving lovastatin after cardiac transplantation [letter]. N Engl J Med. 1988; 318(1):47-48.
    • (1988) N Engl J Med , vol.318 , Issue.1 , pp. 47-48
    • Tobert, J.A.1
  • 35
    • 0032959122 scopus 로고    scopus 로고
    • Long-term safety of pravastatin-gemfibrozil therapy in mixed hyperlipidemia
    • Iliadis EA, Rosenson RS. Long-term safety of pravastatin-gemfibrozil therapy in mixed hyperlipidemia. Clin Cardiol. 1999;22:25-28.
    • (1999) Clin Cardiol , vol.22 , pp. 25-28
    • Iliadis, E.A.1    Rosenson, R.S.2
  • 36
    • 0015348189 scopus 로고
    • Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 37
    • 0037143688 scopus 로고    scopus 로고
    • ACC/AHA/NHLBI Clinical Advisory on the use and safety of statins
    • Pasternak RC, Smith SC Jr, Bairey-Merz CN, et al. ACC/AHA/NHLBI Clinical Advisory on the use and safety of statins. Circulation. 2002;106:1024-1028.
    • (2002) Circulation , vol.106 , pp. 1024-1028
    • Pasternak, R.C.1    Smith S.C., Jr.2    Bairey-Merz, C.N.3
  • 38
    • 85039627662 scopus 로고    scopus 로고
    • Statins are not all alike: Study reveals no increased risk of musculoskletal effects
    • From data presented at the XIV International Symposium on Drugs Affecting lipid Metabolism (DALM), September 9-12
    • Statins are not all alike: study reveals no increased risk of musculoskletal effects. From data presented at the XIV International Symposium on Drugs Affecting lipid Metabolism (DALM), MediView Express Report. September 9-12, 2001.
    • (2001) MediView Express Report
  • 39
    • 0035434397 scopus 로고    scopus 로고
    • Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins)
    • Igel M, Sudhop T, Bergmann K. Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins). Eur J Clin Pharmacol. 2001;57:357-364.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 357-364
    • Igel, M.1    Sudhop, T.2    Bergmann, K.3
  • 40
    • 0034533147 scopus 로고    scopus 로고
    • Statins as a newly recognized type of immunomodulator
    • Kwak B, Mulhaupt F, Myit S, et al. Statins as a newly recognized type of immunomodulator. Nat Med. 2000;6:1399-1402.
    • (2000) Nat Med , vol.6 , pp. 1399-1402
    • Kwak, B.1    Mulhaupt, F.2    Myit, S.3
  • 41
    • 0035916305 scopus 로고    scopus 로고
    • Statins alter smooth muscle cell accumulation and collagen content in established atheroma of Watanabe heritable hyperlipidemic rabbits
    • Fukumoto Y, Libby P, Rabkin E, et al. Statins alter smooth muscle cell accumulation and collagen content in established atheroma of Watanabe heritable hyperlipidemic rabbits. Circulation. 2001;103(7):993-999.
    • (2001) Circulation , vol.103 , Issue.7 , pp. 993-999
    • Fukumoto, Y.1    Libby, P.2    Rabkin, E.3
  • 42
    • 0034978090 scopus 로고    scopus 로고
    • Fibromuscular cap composition is important for the stability of established atherosclerotic plaques in mature WHHL rabbits treated with statins
    • Shiomi M, Ito T, Hirouchi Y, et al. Fibromuscular cap composition is important for the stability of established atherosclerotic plaques in mature WHHL rabbits treated with statins. Atherosclerosis. 2001;157:75-84.
    • (2001) Atherosclerosis , vol.157 , pp. 75-84
    • Shiomi, M.1    Ito, T.2    Hirouchi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.