Chemo-enzymatic synthesis of (R)-(+)-aminoglutethimide by kinetic resolution of (±)-4-cyano-4-phenyl-1-hexanol

Journal of Molecular Catalysis B: Enzymatic

Volumn 26, Issue 3-6, 2003, Pages 185-191

  Im, Dai Sig ^b   Cheong, Chan Seong ^a   Lee, So Ha ^a   Jung, Youn Kyoung ^c   Jeong, In Howa ^c  

^a Korea Institute of Science and Technology   (South Korea)

^b Comp Aided Molec Des/Biosci R ^*  (South Korea)

^c Yonsei University Wonju   (South Korea)

Author keywords

Aminoglutethimide; Enantioselective; Enzymatic resolution; Tertiary benzylic center; Transesterification

Indexed keywords

ALCOHOLS; AROMATIC COMPOUNDS; DRUG PRODUCTS; ESTERIFICATION; STEREOCHEMISTRY;

KINETIC RESOLUTION;

ENZYMES;

4 CYANO 4 PHENYL 1 HEXANOL; ALCOHOL DERIVATIVE; AMINOGLUTETHIMIDE; AROMATASE INHIBITOR; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; BURKHOLDERIA CEPACIA; CATALYST; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; NONHUMAN; PSEUDOMONAS FLUORESCENS; TRANSESTERIFICATION;

BURKHOLDERIA CEPACIA; PSEUDOMONAS; PSEUDOMONAS FLUORESCENS;

EID: 0242659249     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcatb.2003.06.001     Document Type: Article

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