Interleukin-6 levels in hyperemesis gravidarum

Archives of Gynecology and Obstetrics

Volumn 269, Issue 1, 2003, Pages 13-15

  Kuscu, Naci K ^a   Yildirim, Yasemin ^a   Koyuncu, Faik ^a   Var, Ahmet ^a   Uyanik, Bekir S ^a  

^a CELAL BAYAR UNIVERSITY   (Turkey)

Author keywords

Hyperemesis; IL 6; Pregnancy; Thyroid

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; INTERLEUKIN 6; THYROID HORMONE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEMALE; GESTATIONAL AGE; HORMONE RELEASE; HUMAN; HYPEREMESIS GRAVIDARUM; HYPERTHYROIDISM; TROPHOBLAST;

ADULT; CHORIONIC GONADOTROPIN; FEMALE; HUMANS; HYPEREMESIS GRAVIDARUM; INTERLEUKIN-6; PREGNANCY; PREGNANCY TRIMESTER, FIRST; STATISTICS, NONPARAMETRIC; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE;

EID: 0242641533     PISSN: 09320067     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00404-002-0412-6     Document Type: Article

References (16)

1. Agarwal R, Loganath A, Roy AC, Wong YC, Lindoff C, Ng SC (2000) Increased expression of interleukin 6 in term compared to the first trimester human placental villi. Horm Metab Res 332:164-168
2. Asakura H, Watanabe S, Sekiguchi A, Power GC, Araki T (2000) Severity of hyperemesis gravidarum correlates with serum levels of reverse T3. Arch Gynecol Obstet 264:57-62
3. Fairweather DVI, Loraine JA (1968) Nausea and vomiting in pregnancy. Am J Obstet Gynecol 102:135-173
4. Goodwin TM, Montero M, Mestman JH (1992) Transient hyperthyroidism and hyperemesis gravidarum: clinical aspects. Am J Obstet Gynecol 167:648-652
5. Hershman JM (1999) Human chorionic gonadotropin and the thyroid: hyperemesis gravidarum and trophoblastic tumors. Thyroid 9:653-657
6. Jauniaux E, Gulbis B, Schandene L, Collette J, Hustin J (1996) Distribution of interleukin-6 in maternal and embryonic tissues during the first trimester. Mol Hum Reprod 2:239-243
7. Kameda T, Matsuzaki N, Sawai K, Okada T, Saji F, Matsuda T, Hirano T, Kishimoto T, Tanizawa O (1990) Production of interleukin-6 by normal human trophoblast. Placenta 11:205-213
8. Leylek OA, Tayaksi M, Ercelsan T, Dokmetas S (1999) Immunologic and biochemical factors in hyperemesis gravidarum with or without hyperthyroxinemia. Gynecol Obstet Invest 47:229-234
9. Masuhiro K, Matsuzaki N, Nishino E, Taniguchi T, Kameda T, Li Y, Saji F, Tanizawa O (1991) Trophoblast-derived interleukin-1 (IL-1) stimulates the release of human chorionic gonadotropin by activating IL-6 and IL-6-receptor system in the first trimester human trophoblasts. J Clin Endocrinol Metab 72:594-601
10. Matsuzaki N, Neki R, Sawai K, Shimoya K, Okada T, Sakata M, Saji F, Koishihara Y, Ida N (1995) Soluble interleukin-6 (IL-6) receptor in the sera of pregnant women forms a complex with IL-6 and augments human chorionic gonadotropin production by normal human trophoblasts through binding to the IL-6 signal transducer. J Clin Endocrinol Metab 80:2912-2917
11. Meisser A, Cameo P, Islami D, Campana A, Bischof P (1999) Effects of interleukin-6 (IL-6) on cytotrophoblastic cells. Mol Hum Reprod 5:1055-1058
12. Nishino E, Matsuzaki N, Masuhiro K, Kameda T, Taniguchi T, Takagi T, Saji F, Tanizawa O (1990) Trophoblast-derived interleukin-6 (IL-6) regulates human chorionic gonadotropin release through IL-6 receptor on human trophoblasts. J Clin Endocrinol Metab 71:436-441
13. Rodien P, Bremont C, Sanson M-LR et al (1998) Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin. N Engl J Med 339:1823-1826
14. Safari HR, Fassett MJ, Souter IC, Alsulyman OM, Goodwin TM (1998) The efficacy of methylprednisolone in the treatment of hyperemesis gravidarum: a randomized, double-blind, controlled study. Am J Obstet Gynecol 179:921-924
15. Taylor R (1996) Successful management of hyperemesis gravidarum using steroid therapy. QJM 89:103-107
16. Yanushpolsky EH, Ozturk M, Polgar K, Berkowitz RS, Hill JA (1993) The effects of cytokines on human chorionic gonadotropin (hCG) production by a trophoblast cell line. J Reprod Immunol 25:235-247