The place of capillary electrophoresis techniques in screening for haemoglobinopathies

Annals of Clinical Biochemistry

Volumn 40, Issue 6, 2003, Pages 659-662

  Gulbis, Béatrice ^a   Fontaine, Bernard ^a   Vertongen, Françoise ^a   Cotton, Frédéric ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; HEMOGLOBIN A; HEMOGLOBIN C; HEMOGLOBIN H; HEMOGLOBIN S;

ADULT; ARTICLE; BLOOD SAMPLING; CAPILLARY ZONE ELECTROPHORESIS; CATION EXCHANGE; CONTROLLED STUDY; DNA STRUCTURE; EVALUATION; HEMOGLOBINOPATHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; ISOELECTRIC FOCUSING; MAJOR CLINICAL STUDY; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; NEWBORN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN STRUCTURE; SCREENING TEST; STRUCTURE ANALYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, MICELLAR ELECTROKINETIC CAPILLARY; EDETIC ACID; ELECTROPHORESIS, CAPILLARY; HEMOGLOBINOPATHIES; HEMOGLOBINS; HUMANS; ISOELECTRIC FOCUSING; MASS SCREENING; MUTATION; PROTEIN CONFORMATION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0242637346     PISSN: 00045632     EISSN: None     Source Type: Journal    
DOI: 10.1258/000456303770367261     Document Type: Article

References (16)

1. Lin C, Cotton F, Fontaine B, Gulbis B, Janssens J, Vertongen F. Capillary zone electrophoresis: an additional technique for the identification of haemoglobin variants. Hemoglobin 1999; 23: 97-109
2. Cotton F, Lin C, Fontaine B, Gulbis B, Janssens J, Vertongen F. Evaluation of a capillary electrophoresis method for routine determination of haemoglobins A2 and F. Clin Chem 1999; 45: 237-43
3. Lin C, Gulbis B, Delobbe E, Cotton F, Vertongen F. Separation of human globin chains by micellar electrokinetic capillary chromatography. J Chromatogr B Biomed Sci Appl 1998; 719: 47-54
4. Cotton F, Lin C, Fontaine B, Gulbis B, Janssens J, Vertongen F. Evaluation of a capillary electrophoresis method for routine determination of haemoglobins A2 and F. Clin Chem 1999; 45: 237-43
5. Lin C, Gulbis B, Delobbe E, Robberecht P, Cotton F, Fontaine B, et al. Could capillary zone electrophoresis of tryptic peptides be used for the characterization of haemoglobin variants? Hemoglobin 2001; 25: 259-72
6. Lin C, Gulbis B, Delobbe E, Cotton F, Vertongen F. Separation of human globin chains by micellar electrokinetic capillary chromatography. J Chromatogr B Biomed Sci Appl 1998; 719: 47-54
7. Gulbis B, Tshilolo L, Cotton F, Lin C, Vertongen F. Newborn screening for haemoglobinopathies: the Brussels experience. J Med Screen 1999; 6: 11-5
8. Lin C, Gulbis B, Delobbe E, Robberecht P, Cotton F, Fontaine B, et al. Could capillary zone electrophoresis of tryptic peptides be used for the characterization of haemoglobin variants? Hemoglobin 2001; 25: 259-72
9. Wajcman H, Barkdadjian J, Ducrocq R. Structural characterization of abnormal haemoglobins from dried blood specimens in a neonatal screening program. Ann Biol Clin 1993; 50: 867-70
10. Kim JW, Park JH, Park JW, Doh HJ, Heo GS, Lee KJ. Quantitative analysis of serum proteins separated by capillary electrophoresis. Clin Chem 1993; 39: 689-92
11. Doelman CJ, Siebelder CW, Nijhof WA, Weykamp CW, Janssens J, Penders TJ. Capillary electrophoresis system for haemoglobin A1c determinations evaluated. Clin Chem 1997; 43: 644-8
12. Mario N, Baudin B, Bruneel A, Janssens J, Vaubourdolle M. Capillary zone electrophoresis for the diagnosis of congenital haemoglobinopathies. Clin Chem 1999; 45: 285-8
13. Gerritsma J, Sinnige D, Drieze C, Sittrop B, Houtsma P, Hulshorst-Jansen N, et al. Quantitative and qualitative analysis of haemoglobin variants using capillary zone electrophoresis. Ann Clin Biochem 2000; 37: 380-9
14. Shihabi ZK, Hinsdale ME, Daugherty HK Jr. Haemoglobin A2 quantification by capillary zone electrophoresis. Electrophoresis 2000; 21: 749-52
15. Mohammad AA, Okorodudu AO, Bissell MG, Dow P, Reger G, Meier A, et al. Clinical application of capillary isoelectric focusing on fused silica capillary for determination of haemoglobin variants. Clin Chem 1997; 43: 1798-9
16. Jenkins MA, Ratnaike S. Capillary isoelectric focusing of haemoglobin variants in the clinical laboratory. Clin Chim Acta 1999; 289: 121-32