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1
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0027248530
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and references cited therein
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Smith R.G., Cheng K., Schoen W.R., Pong S.-S., Hickey G., Jacks T., Butler B., Chan W.W.-S., Chaung L.-Y.P., Judith F., Taylor J., Wyvratt M.J., Fisher M.H. Science. 260:1993;1640-1643. and references cited therein.
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(1993)
Science
, vol.260
, pp. 1640-1643
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-
Smith, R.G.1
Cheng, K.2
Schoen, W.R.3
Pong, S.-S.4
Hickey, G.5
Jacks, T.6
Butler, B.7
Chan, W.W.-S.8
Chaung, L.-Y.P.9
Judith, F.10
Taylor, J.11
Wyvratt, M.J.12
Fisher, M.H.13
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2
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85030951040
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Schoen, W. R.; Wyvratt, M. J.; Smith, R. G. Annual Reports in Medicinal Chemistry Bristol, J. A., Ed.; Academic Press: California, 1993; Vol. 28, Chapter 19.
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4
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15644383589
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DeVita R.J., Bochis R., Frontier A.J., Kotliar A., Fisher M.H., Schoen W.R., Wyvratt M.J., Cheng K., Chan W.W.-S., Butler B., Jacks T.M., Hickey G.J., Schleim K.D., Leung K., Chen Z., Chiu S.-H.L., Feeney W.P., Cunningham P.K., Smith R.G. J. Med. Chem. 41:1998;1716-1728.
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(1998)
J. Med. Chem.
, vol.41
, pp. 1716-1728
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Devita, R.J.1
Bochis, R.2
Frontier, A.J.3
Kotliar, A.4
Fisher, M.H.5
Schoen, W.R.6
Wyvratt, M.J.7
Cheng, K.8
Chan, W.W.-S.9
Butler, B.10
Jacks, T.M.11
Hickey, G.J.12
Schleim, K.D.13
Leung, K.14
Chen, Z.15
Chiu, S.-H.L.16
Feeney, W.P.17
Cunningham, P.K.18
Smith, R.G.19
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5
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0028301205
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Armstrong J.D. III, Eng K.K., Keller J.L., Purick R.M., Hartner F.W. Jr., Choi W.-B, Askin D., Volante R.P. Tetrahedron Lett. 35:1994;3239-3242.
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(1994)
Tetrahedron Lett.
, vol.35
, pp. 3239-3242
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Armstrong III, J.D.1
Eng, K.K.2
Keller, J.L.3
Purick, R.M.4
Hartner Jr., F.W.5
Choi, W.-B.6
Askin, D.7
Volante, R.P.8
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6
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0027250631
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King A.O., Anderson R.K., Shuman R.F., Karady S., Abramson N.L., Douglas A.W. J. Org. Chem. 58:1993;3384-3386.
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(1993)
J. Org. Chem.
, vol.58
, pp. 3384-3386
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-
King, A.O.1
Anderson, R.K.2
Shuman, R.F.3
Karady, S.4
Abramson, N.L.5
Douglas, A.W.6
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7
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85030947485
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Presented at the IBS conference, Peptidomimetics and Small Molecule Design: Accelerating Drug Discovery and Development, Philadelphia, PA, March 10-12, 1997. The edited and updated transcript from this conference was published by IBC in November, 1997 (IBC Library Series publication #984, pp. 163-170).
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Presented at the IBS conference, Peptidomimetics and Small Molecule Design: Accelerating Drug Discovery and Development, Philadelphia, PA, March 10-12, 1997. The edited and updated transcript from this conference was published by IBC in November, 1997 (IBC Library Series publication #984, pp. 163-170).
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8
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85030949891
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Other solvents have been demonstrated on the steroidal substrates only.
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Other solvents have been demonstrated on the steroidal substrates only.
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9
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85030948811
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2 was unsuccessful
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2 was unsuccessful.
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11
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85030951788
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13C 1D NMR as well as a 2D inverse long range correlation experiments were used to characterize the adduct.
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13C 1D NMR as well as a 2D inverse long range correlation experiments were used to characterize the adduct.
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12
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0000358994
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2 may occur simply by an extension of an intramolecular Hofmann-Loffler-Freytag reaction.
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13
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0028294987
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Schoen W.R., Pisano J.M., Prendergast K., Wyvratt M.J., Fisher M.H., Cheng K., Chan W.W.-S., Butler B., Smith R.G., Ball R.G. J. Med. Chem. 37:1994;897-906 Breaking of the D-pyroglutamic salt of 2 was accomplished by partitioning between THF and NaCl saturated concentrated ammonia. Examination of the THF extract by Dionex ion chromatography showed only traces (< 10 ppm) of pyroglutamic acid.
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(1994)
J. Med. Chem.
, vol.37
, pp. 897-906
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Schoen, W.R.1
Pisano, J.M.2
Prendergast, K.3
Wyvratt, M.J.4
Fisher, M.H.5
Cheng, K.6
Chan, W.W.-S.7
Butler, B.8
Smith, R.G.9
Ball, R.G.10
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15
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0000795317
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Smith G.B., Dezeny G.C., Hughes D.L., King A.O., Verhoeven T.R. J. Org. Chem. 59:1994;8151-8156.
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(1994)
J. Org. Chem.
, vol.59
, pp. 8151-8156
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Smith, G.B.1
Dezeny, G.C.2
Hughes, D.L.3
King, A.O.4
Verhoeven, T.R.5
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16
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0000340791
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For the preparation of (2-formylphenyl)boronic acid, see:
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For the preparation of (2-formylphenyl)boronic acid, see: Wytko J.A., Graf E., Weiss J. J. Org. Chem. 57:1992;1015-1018.
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(1992)
J. Org. Chem.
, vol.57
, pp. 1015-1018
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Wytko, J.A.1
Graf, E.2
Weiss, J.3
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17
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0000844109
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Abdel-Magid A.F., Carson K.G., Harris B.D., Maryanoff C.A., Shah R.D. J. Org. Chem. 61:1996;3849-3862.
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(1996)
J. Org. Chem.
, vol.61
, pp. 3849-3862
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Abdel-Magid, A.F.1
Carson, K.G.2
Harris, B.D.3
Maryanoff, C.A.4
Shah, R.D.5
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18
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85030940542
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The structures of dibenzyl amine and tribenzyl amine are: Apparently the reaction of the primary imine with the mono or dibenzyl amine occurred faster than the reduction of the primary imine.
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The structures of dibenzyl amine and tribenzyl amine are: Apparently the reaction of the primary imine with the mono or dibenzyl amine occurred faster than the reduction of the primary imine.
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20
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0031550856
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Armstrong J.D. III, Wolfe C.N., Keller J.L., Lynch J., Bhupathy M., Volante R.P., DeVita R.J. Tetrahedron Lett. 38:1997;1531-1532.
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(1997)
Tetrahedron Lett.
, vol.38
, pp. 1531-1532
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Armstrong III, J.D.1
Wolfe, C.N.2
Keller, J.L.3
Lynch, J.4
Bhupathy, M.5
Volante, R.P.6
Devita, R.J.7
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21
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85030951702
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For bulk drug products, no more than 10 ppm of any heavy metal may be present in the final product.
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For bulk drug products, no more than 10 ppm of any heavy metal may be present in the final product.
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