Differential regulation of in vivo angiogenesis by angiotensin II receptors

FASEB Journal

Volumn 17, Issue 14, 2003, Pages 2061-2067

  Walther, Thomas ^b   Menrad, Andreas ^a   Orzechowski, Hans Dieter ^b   Siemeister, Gerhard ^a   Paul, Martin ^b   Schirner, Michael ^a  

^a BAYER PHARMA AG   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Alginate implant angiogenesis; Angiotensin receptor AT1; Angiotensin receptor AT2

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ALGINIC ACID; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN RECEPTOR; BRADYKININ ANTAGONIST; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; ICATIBANT; LOSARTAN;

ANGIOGENESIS; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMPLANT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ALGINATES; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANGIOTENSINOGEN; ANIMALS; CELL LINE, TUMOR; ENALAPRIL; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, NUDE; MICE, TRANSGENIC; MICROSPHERES; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN;

ANIMALIA; MUS MUSCULUS;

EID: 0242611523     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.03-0129com     Document Type: Article

References (25)

1. Risau, W. (1997) Mechanisms of angiogenesis. Nature (London) 386, 671-674
2. Millauer, B., Shawver, L. K., Plate, K. H., Risau, W., and Ullrich, A. (1994) Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature (London) 367, 576-579
3. Maisonpierre, P. C., Suri, C., Jones, P. F., Bartunkova, S., Wiegand, S. J., Radziejewski, C., Compton, D., McClain, J., Aldrich, T. H., Papadopoulos, N., et al. (1997) Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277, 55-60
4. Stoll, M., Steckelings, U. M., Paul, M., Bottari, S. P., Metzger, R., and Unger, T. (1995) The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. J. Clin. Invest. 95, 651-657
5. Le Noble, F. A., Schreurs, N. H., van Straaten, H. W., Slaaf, D. W., Smits, J. F., Rogg, H., and Struijker-Boudier, H. A. (1993) Evidence for a novel angiotensin II receptor involved in angiogenesis in chick embryo chorioallantoic membrane. Am. J. Physiol. 264, R460-R465
6. Fernandez, L. A., Twickler, J., and Mead, A. (1985) Neovascularization produced by angiotensin II. J. Lab. Invest. Clin. 105, R141-R145
7. Walsh, D. A., Hu, D. E., Wharton, J., Catravas, J. D., Blake, D. R., and Fan, T. P. (1997) Sequential development of angiotensin receptors and angiotensin I converting enzyme during angiogenesis in the rat subcutaneous sponge granuloma. Br. J. Pharmacol. 120, 1302-1311
8. Grady, E. F., Sechi, L. A., Griffin, C. A., Schambelan, M., and Kalinyak, J. E. (1991) Expression of AT2 receptors in the developing rat fetus. J. Clin. Invest. 88, 921-933
9. Ahmed, A., Li, X. F., Shams, M., Gregory, J., Rollason, T., Barnes, N. M., and Newton, J. R. (1995) Localization of the angiotensin II and its receptor subtype expression in human endometrium and identification of a novel high-affinity angiotensin II binding site. J. Clin. Invest. 96, 848-857
10. Viswanathan, M., and Saavedra, J. M. (1992) Expression of angiotensin II AT2 receptors in the rat skin during experimental wound healing. Peptides 13, 783-786
11. Nakajima, M., Hutchinson, H. G., Fujinaga, M., Hayashida, W., Morishita, R., Zhang, L., Horiuchi, M., Pratt, R. E., and Dzaum, V. J. (1995) The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer. Proc. Natl. Acad. Sci. USA 92, 10663-10667
12. Hein, L., Barsh, G. S., Pratt, R. E., Dzau, V. J., and Kobilka, B. K. (1995) Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice. Nature (London) 377, 744-747
13. Unger, T., Mattfeldt, T., Lamberty, V., Bock, P., Mall, G., Linz, W., Scholkens, B. A., and Gohlke, P. (1992) Effect of early onset angiotensin converting enzyme inhibition on myocardial capillaries. Hypertension 20, 478-482
14. Fabre, J. E., Rivard, A., Magner, M., Silver, M., and Isner, J. M. (1999) Tissue inhibition of angiotensin-converting enzyme activity stimulates angiogenesis in vivo. Circulation 99, 3043-3049
15. Hoffmann, J., Schirner, M., Menrad, A., and Schneider, M. R. (1997) A highly sensitive model for quantification of in vivo tumor angiogenesis induced by alginate-encapsulated tumor cells. Cancer Res. 57, 3847-3851
16. Schirner, M., Hoffmann, J., Menrad, A., and Schneider, M. R. (1998) Antiangiogenic chemotherapeutic agents: characterization in comparison to their tumor growth inhibition in human renal cell carcinoma models. Clin. Cancer Res. 4, 1331-1336
17. Plunkett, M. L., and Hailey, J. A. (1990) An in vivo quantitative angiogenesis model using tumor cells entrapped in alginate. Lab. Invest. 62, 510-517
18. Minchenko, A., Bauer, T., Salceda, S., and Caro, J. (1994) Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab. Invest. 71, 374-379
19. Kimura, S., Mullins, J. J., Bunnemann, B., Metzger, R., Hilgenfeldt, U., Zimmermann, F., Jacob, H., Fuxe, K., Ganten, D., and Kaling, M. (1992) High blood pressure in transgenic mice carrying the rat angiotensinogen gene. EMBO J. 11, 821-827
20. Ichiki, T., Labosky, P. A., Shiota, C., Okuyama, S., Imagawa, Y., Fogo, A., Niimura, F., Ichikawa, I., Hogan, B. L., and Inagami, T. (1995) Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Nature (London) 377, 748-750
21. Curnow, K. M., Pascoe, L., Davies, E., White, P. C., Corvol, P., and Clauser, E. (1995) Alternatively spliced human type 1 angiotensin II receptor mRNAs are translated at different efficiencies and encode two receptor isoforms. Mol. Endocrinol. 9, 1250-1262
22. Silvestre, J. S., Bergaya, S., Tamarat, R., Duriez, M., Boulanger, C. M., and Levy, B. I. (2001) Proangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway. Circ. Res. 89, 678-683
23. Ozawa, Y., Suzuki, Y., Murakami, K., and Miyazaki, H. (1996) The angiotensin II type 2 receptor primarily inhibits cell growth via pertussis toxin-sensitive G proteins. Biochem. Biophys. Res. Commun. 228, 328-333
24. Silvestre, J. S., Tamarat, R., Senbonmatsu, T., Icchiki, T., Ebrahimian, T., Iglarz, M., Besnard, S., Duriez, M., Inagami, T., and Levy, B. I. (2002) Antiangiogenic effect of angiotensin II type 2 receptor in ischemia-induced angiogenesis in mice hindlimb. Circ. Res. 90, 1072-1079
25. Timmermans, P. B., Wong, P. C., Chiu, A. T., Herblin, W. F., Benfield, P., Carini, D. J., Lee, R.J., Wexler, R. R., Saye, J. A., and Smith, R. D. (1993) Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol. Rev. 45, 205-251