Evaluating HPLC Assay Robustness with Experimental Design

Journal of Liquid Chromatography and Related Technologies

Volumn 26, Issue 18, 2003, Pages 2975-2985

  Waters, Robert B ^a   Dovletoglou, Angelos ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

HPLC assay robustness; Plackett Burman design; Statistical evaluation

Indexed keywords

ASSAYS; FERMENTATION; LIQUID CHROMATOGRAPHY; TAILINGS;

SCREENING FACTORIAL EXPERIMENTAL DESIGNS;

ROBUSTNESS (CONTROL SYSTEMS);

PNEUMOCANDIN B0; PNEUMOCANDIN DERIVATIVE; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; ARTICLE; CALCULATION; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; COMPUTER PROGRAM; EVALUATION; EXPERIMENTAL DESIGN; FACTORIAL ANALYSIS; FERMENTATION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LABORATORY TEST; MEASUREMENT; PARAMETER; SCREENING TEST; SEPARATION TECHNIQUE; STATISTICAL ANALYSIS; TEMPERATURE DEPENDENCE;

EID: 0242609354     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-120025411     Document Type: Article

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