Occurrence of the carcinogenic Bracken constituent ptaquiloside in fronds, topsoils and organic soil layers in Denmark

Chemosphere

Volumn 51, Issue 2, 2003, Pages 117-127

  Rasmussen, Lars H ^a   Kroghsbo, Stine ^b   Frisvad, Jens C ^b   Hansen, Hans Christian B ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Biotoxins; Cancer; Leaching; Pteridium; Soil contamination; Vegetation

Indexed keywords

ECOSYSTEMS; FOOD PRODUCTS; PLANTS (BOTANY); SOILS; TUMORS;

FERNS;

CARCINOGENS;

CARCINOGEN; DRINKING WATER; PTAQUILOSIDE; TOXIN;

CARCINOGEN; LEACHING; SOIL POLLUTION; TOXIN; VEGETATION;

ANTARCTICA; ARTICLE; BIOMASS; CARCINOGENESIS; DENMARK; ECOSYSTEM; FERN; FOOD; LEACHING; PLANT; POLLUTION TRANSPORT; PRECIPITATION; QUANTITATIVE ANALYSIS; SOIL POLLUTION; VEGETATION;

DENMARK;

FILICOPHYTA; POLYPODIACEAE; PTERIDIUM; PTERIDIUM AQUILINUM;

EID: 0242600587     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0045-6535(02)00694-X     Document Type: Article

References (39)

1. Agnew, M.P., Lauren, D.R., 1991. Determination of ptaquiloside in bracken fern (Pteridium esculentum). J. Chromatogr. 538, 462-468.
2. Alonso-Amelot, M.E., 1997. The link between bracken fern and stomach cancer: milk. Nutrition 13, 694-696.
3. Alonso-Amelot, M.E., Rodulfo-Baechler, S., Jaimes-Espinosa, R., 1995. Comparative dynamics of ptaquiloside and pterosin B in the two varieties (caudatum and arachnoideum) of neotropical bracken fern (Pteridium aquilinum L. Kuhn). Biochem. Syst. Ecol. 23, 709-716.
4. Alonso-Amelot, M.E., Castillo, U.F., Smith, B.L., Lauren, D.R., 1996. Bracken ptaquiloside in milk. Nature 382, 587.
5. Alonso-Amelot, M.E., Castillo, U.F., Smith, B.L., Lauren, D.R., 1998. Excretion through milk, of ptaquiloside in bracken-fed cows. A quantitative assessment. Lait 78, 413-423.
6. Alonso-Amelot, M.E., Calcagno, M.P., Pérez-Inojosa, M., 2000. Growth and selective defensive potential in relation to altitude in neotropical Pteridium aquilinum var. caudatum. In: Taylor, J.A., Smith, R.T. (Eds.), Bracken Fern: Toxicity, Biology and Control. Proceedings of the International Bracken Group Conference Manchester 1999. Aberystwyth, Wales, pp. 43-47.
7. Alonso-Amelot, M.E., Pérez-Mena, M., Calcagno, M.P., Jaimes-Espinosa, R., Castillo, U.F., 1992. Ontogenic variation of biologically active metabolites of Pteridium aquilinum (L. Kuhn), pterosins A and B, ptaquiloside in a bracken population of the tropical Andes. J. Chem. Ecol. 18, 1405-1420.
8. Ames, B.N., Gold, L.S., 1990. Dietary carcinogens, environmental pollution, and cancer: some misconceptions. Med. Onc. Tumor Pharm. 7, 69-85.
9. Burkhalter, P.W., Groux, P.M.J., Candrian, U., Hübner, P., Lüthy, J., 1996. Isolation, determination and degradation of ptaquiloside - a bracken fern (Pteridium aquilinum) carcinogen. J. Nat. Toxins 5, 141-159.
10. Castillo, U.F., Ojika, M., Alonso-Amelot, M.E., Sakagami, Y., 1998. Ptaquiloside Z, a new toxic unstable sesquiterpene glucoside from the neotropical bracken fern Pteridium aquilinum var. caudatum. Bioorg. Med. Chem. 6, 2229-2233.
11. Castillo, U.F., Wilkins, A.L., Lauren, D.R., Smith, B.L., Towers, N.R., Alonso-Amelot, M.E., Jaimez-Espinoza, R., 1997. Isoptaquiloside and caudatoside, illudane-type sesquiterpene glucosides from Pteridium aquilinum var. caudatum. Phytochemistry 44, 901-906.
12. Esbensen, K.H., 2000. Multivariate data analysis - in practice, fourth ed. Camo ASA, Oslo, Norway.
13. Evans, I.A., 1979. Bracken carcinogenicity. Res. Vet. Sci. 26, 339-348.
14. Evans, I.A., Galpin, O.P., 1990. Bracken and leukaemia. Lancet 335, 231-231.
15. FAO, 1990. Guidelines for soil description, third ed. Food and Agriculture Organization of the United Nations, Rome, Italy.
16. Galpin, O.P., Smith, R.M.M., 1986. Bracken, stomach cancer and water supplies: is there a link? In: Smith, R.T., Taylor, J.A., (Eds.). Bracken - Ecology, Land Use and Control Technology - The Proceedings of the International Conference - Bracken '85. Parthenon Publishing, Aberystwyth, Wales, pp. 147-159.
17. Galpin, O.P., Whitaker, C.J., Whitaker, R., Kassab, J.Y., 1990. Gastric cancer in Gwynedd. Possible links with bracken. Br. J. Cancer 61, 737-740.
18. Haenszel, W., Kurihara, M., Locke, F.B., Shimuzu, K., Segi, M., 1976. Stomach cancer in Japan. J. Natl. Cancer Inst. 56, 265-274.
19. Hansen, K., 1991. Dansk feltflora (The Danish Field Flora, in Danish). Nordisk Forlag AS, Copenhagen, Denmark.
20. Hirono, I., Shibuya, C., Shimisu, M., Fushimi, K., 1972. Carcinogenic activity of processed bracken used as human food. J. Natl. Cancer Inst. 48, 1245-1249.
21. Kaufman, P.B., Cseke, L.J., Warber, S., Duke, J.A., Brielmann, H.L., 1999. Natural products from plants. CRC Press, Boca Raton, Boston, London, New York, Washington, DC, USA.
22. Nagao, T., Saito, K., Hirayama, E., Uchikoshi, K., Koyama, K., Natori, S., Morisaki, N., Iwasaki, S., Matsushima, T., 1989. Mutagenicity of ptaquiloside, the carcinogen in bracken, and its related illudane-type sesquiterpenes. I. Mutagenicity in Salmonella typhimurium. Mutat. Res. 215, 173-175.
23. Nelson, D.W., Sommers, L.E., 1982. Total carbon, organic carbon, and organic matter. In: Page, A.L., Miller, R.H., Keeney, D.R. (Eds.), Methods of soil analysis. Part 2, 2 ed.. American Society of Aggronomy and Soil Science Society of America, Madison, WI, USA, pp. 539-579.
24. Niwa, H., Ojika, M., Wakamatsu, K., Yamada, K., Hirono, I., Matsushita, K., 1983. Ptaquiloside, a novel norsesquiterpene glucoside from Bracken, Pteridium aquilinum var. latiusculum. Tetrahed. Lett. 24, 4117-4120.
25. Ojika, M., Wakamatsu, K., Niwa, H., Yamada, K., 1987. Ptaquiloside, a potent carcinogen isolated from bracken fern Pteridium aquilinum var. latiusculum: structure elucidation based on chemical and spectral evidence, and reactions with amino acids, nucleosides, and nucleotides. Tetrahedron 43, 5261-5274.
26. Ojika, M., Sugimoto, K., Okazaki, T., Yamada, K., 1989. Modification and cleavage of DNA by ptaquiloside. A new potent carcinogen isolated from bracken fern. J. Chem. Soc., Chem. Commun. 22, 1775-1777.
27. Page, C.N., 1976. The taxonomy and phytogeography of bracken - a review. Bot. J. Linn. Soc. 73, 1-34.
28. Paterson, S., Pakeman, R.J., Marrs, R., 1997. Evaluation of a bracken (Pteridium aquilinum (L.) Kuhn) growth model in predicting the effects of control strategies across a range of climatic zones in Great Britain. Ann. Appl. Biol. 130, 305-318.
29. Rasmussen, L.H., Hansen, H.C.B., 2003. Growth of bracken in Denmark and the content of ptaquiloside in fronds, rhizomes and roots. In: Proceedings of the 6th International Symposium on Poisoneous Plants, in press.
30. Rasmussen, L.H., Jensen, L.S., Hansen, H.C.B., 2003. Distribution of the carcinogenic terpene ptaquiloside in bracken fronds, rhizomes (Pteridium aquilinum) and litter in Denmark. J. Chem. Ecol., in press.
31. Saito, M., Nagao, T., Matoba, M., Koyama, K., Natori, S., Murakami, T., Saiki, Y., 1989. Chemical assay of ptaquiloside, the carcinogen of Pteridium aquilinum, and the distribution of related compounds in the Pteridaceae. Phytochemistry 28, 1605-1611.
32. Smith, B.L., 1997. The toxicity of bracken fern (genus Pteridium) to animals and its relevance to man. In: Felix D'Mello, J.P. (Ed.), Handbook of plant and fungal toxicants. CRC Press, New York, USA, pp. 63-76.
33. Smith, B.L., Seawright, A.A., Ng, J.C., Hertle, A.T., Thomson, J.A., Bostock, P.D., 1994. Concentration of ptaquiloside, a major carcinogen in bracken fern (Pteridium spp.), from eastern Australia and from a cultivated worldwide collection held in Sydney, Australia. Nat. Toxins 2, 347-353.
34. Sundberg, P.S., Callesen, I., Greve, M.H., Raulund-Rasmussen, K., 1999. Danske jordbundsprofiler. Danmarks Jordbrugsforskning, Viborg, Denmark (in Danish).
35. Taylor, J., 1999. Perceptions of bracken. In: Taylor, J. (Ed.). Bracken Perceptions and Bracken Control in the British uplands. Papers given at a meeting held at the University of Lancaster, UK on 10th September 1998. The International Bracken Group, Ceredigion, England, pp. 1-7.
36. van der Hoeven, J.C.M., Lagerweij, W.J., Posthumus, M.A., Veldhuizen, A., Holterman, H.A.J., 1983. Aquilide A, a new mutagenic compound isolated from bracken fern (Pteridium aquilinum (L.) Kuhn). Carcinogenesis 4, 1587-1590.
37. Vesterdal, L., 1998. Forest floors as affected by tree species, thinning intensity, and soil properties. Ph.D. Thesis. Unit of Forestry, The Royal Veterinary and Agricultural University, Denmark.
38. Villalobos-Salazar, J., Hernandez, H., Meneses, A., Salazar, G., 2000. Factors which may affect ptaquiloside levels in milk: effects of altitude, bracken fern growth stage, and milk processing. In: Taylor, J.A., Smith, R.T. (Eds.). Bracken fern: Toxicity, Biology and Control. Proceedings of the International Bracken Group Conference Manchester 1999, IBG, Aberystwyth, Wales, pp. 68-74.
39. Watt, A.S., 1976. The ecological status of bracken. Bot. J. Linn. Soc. 73, 217-239.