Treatment of idiopathic sudden sensorineural hearing loss with antiviral therapy: A prospective, randomized, double-blind clinical trial

Annals of Otology, Rhinology and Laryngology

Volumn 112, Issue 11, 2003, Pages 993-1000

  Westerlaken, Boris Olivier ^a   Stokroos, Robert Jan ^b   Wit, Hero Piet ^a   Dhooge, Inge Johanna Maria ^c   Albers, Frans Willem Jan ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Acyclovir; Clinical trial; Sudden hearing loss; Therapy

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; CORTICOSTEROID; PREDNISOLONE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; HEADACHE; HEART PALPITATION; HERPES VIRUS; HUMAN; HYPERGLYCEMIA; LABYRINTHITIS; MALE; MULTICENTER STUDY; NAUSEA; PERCEPTION DEAFNESS; PRESSURE SENSE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SPEECH AUDIOMETRY; TINNITUS; TREATMENT OUTCOME; VERTIGO;

EID: 0242594655     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348940311201113     Document Type: Article

References (22)

1. Vasama JP, Linthicum FH Jr. Idiopathic sudden sensorineural hearing loss: temporal bone histopathologic study. Ann Otol Rhinol Laryngol 2000;109:527-32.
2. Van Dishoeck HAE, Bierman TA. Sudden perceptive deafness and viral infection. Report of the first one hundred patients. Ann Otol Rhinol Laryngol 1957;66:963-80.
3. Veltri RW, Wilson WR, Sprinkle PM, Rodman SM, Kavesh DA. The implication of viruses in idiopathic sudden fiearing loss: primary infection or reactivation of latent viruses? Otolaryngol Head Neck Surg 1981;89:137-41.
4. Fitzgerald DC, Mark AS. Sudden hearing loss: frequency of abnormal findings on contrast-enhanced MR studies. AJNR Am J Neuroradiol 1998;19:1433-6.
5. Schuknecht HF, Kimura RS, Naufal PM. The pathology of sudden deafness. Acta Otolaryngol (Stockh) 1973;76:75-97.
6. Furuta Y, Takasu T, Fukuda S, Inuyama Y, Sato KC, Nagashima K. Latent herpes simplex virus type 1 in human vestibular ganglia. Acta Otolaryngol Suppl (Stockh) 1993(suppl 503): 85-9.
7. Fukuda S, Furuta Y, Takasu T, Suzuki S, Inuyama Y, Nagashima K. The significance of herpes viral latency in the spiral ganglia. Acta Otolaryngol Suppl (Stockh) 1994(suppl 514):108-10.
8. Stokroos RJ, Albers FWJ, Schirm J. The etiology of idiopathic sudden sensorineural hearing loss. Experimental herpes simplex virus infection of the inner ear. Am J Otol 1998;19:447-52.
9. Stokroos RJ, Albers FWJ. Therapy of idiopathic sudden sensorineural hearing loss. A review of the literature. Acta Otorhinolaryngol Belg 1996;50:77-84.
10. Wilson WR, Byl FM, Laird N. The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study. Arch Otolaryngol 1980;106:772-6.
11. Moskowitz D, Lee KJ, Smith HW. Steroid use in idiopathic sudden sensorineural hearing loss. Laryngoscope 1984;94: 664-6.
12. Marsh RJ, Cooper M. Double-masked trial of topical acyclovir and steroids in the treatment of herpes zoster ocular inflammation. Br J Ophthalmol 1991;75:542-6.
13. Wood MJ, Johnson RW, McKendrick MW, Taylor J, Mandal BK, Crooks J. A randomized trial of acyclovir for 7 days or 21 days with and without prednisolone for treatment of acute herpes zoster. N Engl J Med 1994;330:896-900.
14. Stokroos RJ, Albers FWJ, Tenvergert EM. Antiviral treatment of idiopathic sudden sensorineural hearing loss: a prospective, randomized, double-blind clinical trial. Acta Otolaryngol (Stockh) 1998;118:488-95.
15. De Kleyn A. Sudden complete or partial loss of function of the octavus system in apparently normal persons. Acta Otolaryngol (Stockh) 1944;32:407-29.
16. Eisenman DJ, Arts HA. Effectiveness of treatment for sudden sensorineural hearing loss. Arch Otolaryngol Head Neck Surg 2000;126:1161-4.
17. Stokroos RJ, Albers FWJ. The etiology of idiopathic sudden sensorineural hearing loss. A review of the literature. Acta Otorhinolaryngol Belg 1996;50:69-76.
18. Roujeau J-C. Pulse glucocorticoid therapy. The "big shot" revisited. Arch Dermatol 1996;132:1499-502.
19. Roosevelt G, Sheehan K, Grupp-Phelan J, Tanz RR, Listemick R. Dexamethasone in bronchiolitis: a randomised controlled trial. Lancet 1996;348:292-5.
20. Pasricha JS, Das SS. Curative effect of dexamethasone-cyclophosphamide pulse therapy for the treatment of pemphigus vulgaris. Int J Dermatol 1992;31:875-7.
21. Beck RW, Cleary PA, Trobe JD, et al. The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis. The Optic Neuritis Study Group. N Engl J Med 1993;329:1764-9.
22. Smith MD, Ahem MJ, Roberts-Thomson PJ. Pulse steroid therapy in rheumatoid arthritis: can equivalent doses of oral prednisolone give similar clinical results to intravenous methylprednisolone? Ann Rheum Dis 1988;47:28-33.