Modulation of Dorsal Spinocerebellar Responses to Limb Movement. I. Effect of Serotonin

Journal of Neurophysiology

Volumn 90, Issue 5, 2003, Pages 3361-3371

  Bosco, G ^a,b   Rankin, A ^a   Poppele, R E ^a,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c Dept of Neuroscience ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 IODO 2,5 DIMETHOXYAMPHETAMINE; KETANSERIN; SEROTONIN; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SPIPERONE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN STEM; CAT; CONTROLLED STUDY; DOSE RESPONSE; ELECTROSTIMULATION; HINDLIMB; KINEMATICS; LIMB MOVEMENT; NERVE CELL; NERVE CELL NETWORK; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RAPHE NUCLEUS; SENSORY NERVE; SENSORY RECEPTOR; SENSORY STIMULATION; SEROTONINERGIC TRANSMISSION; SPINAL CORD; SPINOCEREBELLAR TRACT; STIMULUS RESPONSE; WAVEFORM;

ANIMALS; CATS; ELECTRIC STIMULATION; EXTREMITIES; MOVEMENT; POSTERIOR HORN CELLS; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SPINOCEREBELLAR TRACTS;

EID: 0242593284     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00203.2003     Document Type: Article

References (35)

1. Berman AL. The Brain Stem of the Cat. Madison, WI: The University of Wisconsin Press, 1968.
2. Bianchi L, Angelini D, Orani GP, and Lacquaniti F. Kinematic coordination in human gait: relation to mechanical energy cost. J Neurophysiol 79: 2155-2170, 1998.
3. Bloedel JR and Courville J. Cerebellar afferent systems In: Handbook of Physiology. The Nervous System. Motor Control. Bethesda, MD: Am. Physiol. Soc, 1981, sect. 1, vol. 2, p. 735-829.
4. Borghese NA, Bianchi L, and Lacquaniti F. Kinematic determinants of human locomotion. J Physiol 494: 863-879, 1996.
5. Bosco G and Poppele RE. Low sensitivity of dorsal spinocerebellar neurons to limb movement speed. Exp Brain Res. 125: 313-322, 1999.
6. Bosco G, Poppele R, and Eian J. Reference frames for spinal proprioception: limb endpoint based or joint-level based? J Neurophysiol 83: 2946-2955. 2000.
7. Bosco G, Rankin A, and Poppele R. Representation of passive hindlimb postures in cat spinocerebellar activity. J Neurophysiol 76: 715-726, 1996.
8. Cullheim S and Arvidsson U. The peptidergic innervation of spinal motoneurons via the bulbospinal 5-hydroxytryptamine pathway. Prog Brain Res 104: 21-40, 1995.
9. Eian J and Poppele RE. A single-camera method for three-dimensional video imaging. J Neurosci Method 20: 65-83, 2002.
10. Hokfelt T, Arvidsson U, Cullheim S, Millhorn D, Nicholas AP, Pieribone V, Seroogy K, and Ulfhake B. Multiple messengers in descending serotonin neurons: localization and functional implications. J Chem Neuroanal 18: 75-86, 2000.
11. Jankowska E, Hammar I, Djouhri L, Heden C, Szabo Lackberg Z, and Yin XK. Modulation of responses of four types of feline ascending tract neurons by serotonin and noradrenaline Eur J Neurosci 9: 1375-1387, 1997a.
12. Jankowska E, Maxwell DJ, Dolk S, and Dahlstrom A. A confocal and electron microscopic study of contacts between 5-HT fibers and feline dorsal horn interneurons in pathways from muscle afferents. J Comp Neurol 387: 430-438, 1997b.
13. Jankowska E, Maxwell DJ, Dolk S, Krutki P, Belichenko PV, and Dahlstrom A. Contacts between serotoninergic fibres and dorsal horn spinocerebellar tract neurons in the cat and rat: a confocal microscopic study. Neuroscience 67: 477-487, 1995.
14. Jankowska E, Simonsberg IH, and Chojnicka B. Modulation of information forwarded to feline cerebellum by monoamines. Ann NY Acad Sci 860: 106-109, 1998.
15. Katz PS and Edwards DH, Metamodulation: the control and modulation of neuromodulation. In: Beyond Neurotransmission, edited by Katz PS. New York: Oxford, 1999, p. 349-382.
16. Kubota S and Poppele RE. Evidence for control of DSCT activity by the brain stem reticular formation. Brain Res 129: 361-365, 1977.
17. Lacquaniti F, Le Taillanter M, Lopiano L, and Maioli C. The control of limb geometry in cat posture. J Physiol 426: 177-192, 1990.
18. Maioli C and Poppele RE. Parallel processing of multisensory information concerning self-motion. Exp Brain Res 87: 119-125, 1991.
19. Matsushita M, Hosoya Y, and Ikeda M. Anatomical organization of the spinocerebellar system in the cat, as studied by retrograde transport of horseradish peroxidase. J Comp Neurol 184: 81-106, 1979.
20. Maxwell DJ and Jankowska E. Synaptic relationships between serotonin-immunoreactive axons and dorsal horn spinocerebellar tract cells in the cat spinal cord. Neurosci. 70: 247-253, 1996.
21. Maxwell L, Maxwell DJ, Neilson M, and Kerr R. A confocal microscopic survey of serotoninergic axons in the lumbar spinal cord of the rat: colocalization with glutamate decarboxylase and neuropeptides. Neurosci. 75: 471-480, 1996.
22. McQuade R and Sharp T. Release of cerebral 5-hydroxytryptamine evoked by electrical stimulation of the dorsal and median raphe nuclei: effect of a neurotoxic amphetamine. Neuroscience 68: 1079-1088, 1995.
23. Osborn CE and Poppele RE. Parallel distributed network characteristics of the DSCT. J Neurophysiol 68: 1100-1112, 1992.
24. Osborn CE and Poppele RE. Sensory integration by the dorsal spinocerebellar tract circuitry. Neurosci. 54: 945-956, 1993.
25. Pearson JC, Sedivec MJ, Dewey DE, and Fyffe RE. Light microscopic observations on the relationships between 5-hydroxytryptamine-immunoreactive axons and dorsal spinocerebellar tract cells in Clarke's column in the cat. Exp Brain Res. 130: 320-327, 2000.
26. Poppele RE, Bosco G, and Rankin A. Independent representations of limb axis length and orientation in spinocerebellar response components. J Neurophysiol 87: 409-422, 2002.
27. Quevedo J, Eguibar JR, Jimenez I, and Rudomin P. Raphe magnus and reticulospinal actions on primary afferent depolarization of group I muscle afferents in the cat. J Physiol 482: 623-640, 1995.
28. Rankin AM, Bosco G, and Poppele RE. Serotonin (5-HT) controls intrinsic modulation in spinocerebellar circuitry. Soc Neurosci Abstr 24: 361.20, 1998.
29. Sorkin LS, McAdoo DJ, and Willis WD. Raphe magnus stimulation-induced antinociception in the cat is associated with release of amino acids as well as serotonin in the lumbar dorsal horn. Brain Res 618: 95-108, 1993.
30. Svensson E, Grillner S, and Parker D. Gating and braking of short- and long-term modulatory effects by interactions between colocalized neuromodulators. J Neurosci 21: 5984-5992, 2001.
31. van Zwieten PA, Blauw GJ, and van Brummelen P. Serotonergic receptors and drugs in hypertension. Pharmacol Toxicol 70: S17-22, 1992.
32. Wessendorf MW and Elde R. The coexistence of serotonin- and substance P-like immunoreactivity in the spinal cord of the rat as shown by immunofluorescent double labeling. J Neurosci 7: 2352-2363, 1987.
33. Wilkinson L. The System for Statistics. Evanston, IL: SYSTAT, 1990.
34. Willis WD. The raphe-spinal system. In Brainstem Control of Spinal Cord Function. London: Academic, 1984, p. 141-214.
35. Wu W, Elde R, and Wessendorf MW. Organization of the serotonergic innervation of spinal neurons in rats. III. Differential serotonergic innervation of somatic and parasympathetic preganglionic motoneurons as determined by patterns of co-existing peptides. Neuroscience 55: 223-233, 1993.