Evaluation of a freeze-dried kit for EDTMP-based bone-seeking radiopharmaceuticals

Applied Radiation and Isotopes

Volumn 58, Issue 4, 2003, Pages 481-488

  Garnuszek, Piotr ^a   Pawlak, Dariusz ^b   Licińska, Iwona ^a   Kamińska, Anna ^c  

^a NATIONAL MEDICINES INSTITUTE   (Poland)

^b SOLTAN INSTITUTE FOR NUCLEAR STUDIES   (Poland)

^c CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

Author keywords

177Lu, 99mTc, Bone seeking radiopharmaceuticals; EDTMP; Freeze dried kit for EDTMP based radiopharmaceuticals; Radiolanthanides

Indexed keywords

BIOMEDICAL ENGINEERING; BONE; CHELATION; DIAGNOSTIC RADIOGRAPHY; FREEZING; SCINTILLATION;

RADIOPHARMACEUTICALS;

ORGANIC ACIDS;

CHELATE; ETHYLENEDIAMINE TETRAKIS(METHYLENEPHOSPHONIC ACID); ETHYLENEDIAMINE TETRAMETHYLENEPHOSPHONIC ACID LU 177; ETHYLENEDIAMINE TETRAMETHYLENEPHOSPHONIC ACID SM 153; ETHYLENEDIAMINE TETRAMETHYLENEPHOSPHONIC ACID TC 99M; LUTETIUM; RADIOPHARMACEUTICAL AGENT; SAMARIUM; TECHNETIUM; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE SCINTISCANNING; CLEARANCE; CLINICAL TRIAL; DRUG DISTRIBUTION; DRUG RETENTION; DRUG UPTAKE; EVALUATION; FREEZE DRYING; HUMAN; MALE; NONHUMAN; PAIN; PALLIATIVE THERAPY; PRIORITY JOURNAL; QUALITY CONTROL; RADIOCHEMISTRY; RADIODIAGNOSIS; RAT; SAFETY; SHELF LIFE;

EID: 0242585407     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8043(03)00057-5     Document Type: Article

References (27)

1. Alberts A.S., Brighton S.W., Kempff P., Louw W.K., Beek A.V., Kritzinger V., Westerink H.P., van Rensburg A.J. Samarium-153-EDTMP for palliation of ankylosing spondylitis, Paget's disease nd rheumatoid arthritis. J. Nucl. Med. 36(8):1995;1417-1420.
2. 177Lu-EDTMP. a potential therapeutic bone agent Nucl. Med. Commun. 19:1998;587-591.
3. 105Rh-EDTMP and its bone accumulation. Appl. Radiat. Isot. 52(2):2000;211-215.
4. Bayouth J.E., Macey D.J., Kasi L.P., Fossella F.V. Dosimetry and toxicity of samarium-153-EDTMP administered for bone pain due to skeletal metastases. J. Nucl. Med. 35(1):1994;63-69.
5. Bouchet L.G., Bolch W.E., Goddu M., Howell R.W., Rao D.V. Considerations in the selection of radiopharmaceuticals for palliation of bone pain from metastatic osseous lesions. J. Nucl. Med. 41(4):2000;682-687.
6. 177Lu labelled polyaminophosphonates as potential agents for bone pain palliation. Nucl. Med. Commun. 23:2002;67-74.
7. 64Cu] Polish Probl. Med. Nucl. 15(29):2001;71-79.
8. Garnuszek P., Pawlak D., Licińska I. Development of the freeze-dried kit for preparation of EDTMP chelates with radio-lanthanides and Tc-99m. J. Labelled Compd. Radiopharm. 44(Suppl. 1):2001;S614-S616.
9. Goeckeler W.F., Edwards B., Volkert W.A., Holmes R.A., Simon J., Wilson D. Skeletal localization of samarium-153 chelates, potential therapeutic bone agents. J. Nucl. Med. 28:1987;495-504.
10. Hassfjell S.P., Hoff P., Bruland O.S., Alstad J. 212Pb/212Bi-EDTMP - synthesis and biodistribution of a novel bone seeking alpha-emitting radiopharmaceutical. J. Labelled Compd. Radiopharm. 34(8):1994;717-734.
11. 165Er-labelled radiopharmaceuticals Nucl. Med. Commun. 19(3):1998;207-217.
12. 166Ho. J. Chem. Soc. Dalton Trans. 9:1995;1411-1416.
13. 153Sm lexidronam. Drugs Aging. 11(5):1997;413-418.
14. 153Sm in rats. Appl. Radiat. Isot. 45(9):1994;949-953.
15. Lewington V.J. Cancer therapy using bone-seeking isotopes. Phys. Med. Biol. 41(10):1996;2027-2042.
16. Louw W.K., Dormehl I.C., van Rensburg A.J., Hugo N., Alberts A.S., Forsyth O.E., Beverley G., Sweetlove M.A., Marais J., Lotter M.G., van Aswegen A. Evaluation of samarium-153 and holmium-166-EDTMP in the normal baboon model. Nucl. Med. Biol. 23(8):1996;935-940.
17. McEwan A.J. Use of radionuclides for the palliation of bone metastases. Semin. Radiat. Oncol. 10(2):2000;103-114.
18. 99mTc-Sn-EDTMP. freeze-dried kit for bone scanning Nucl. Med. Biol. 25(3):1998;313-315.
19. Nowak, M., Garnuszek, P., Licińska, I., Łukasiewicz, A., Woźniak, I., Zulczyk, W., 1995. [Preparation and examination of properties of Samarium-153-EDTMP complex.]. Polish. IAE Report 18/A.
20. Oh S.J., Won K.S., Moon D.H., Cheon J.H., Ha H.-J., Jeong J.M., Lee H.K. Preparation and biological evaluation of 188Re-ethylenediamine-N,N,N′,N′-tetrakis(methylene phosphonic acid) as potential agent for bone pain palliation. Nucl. Med. Commun. 23:2002;75-81.
21. Rosch F., Herzog H., Plag C., Neumaier B., Braun U., Muller-Gartner H.W., Stocklin G. Radiation doses of yttrium-90 citrate and yttrium-90 EDTMP as determined via analogous yttrium-86 complexes and positron emission tomography. Eur. J. Nucl. Med. 23(8):1996;958-966.
22. Serafini A.N., Houston S.J., Resche I.et al. Palliation of pain associated with metastatic bone cancer using samarium-153 Lexidronam. a double-blind placebo-controlled clinical trial J. Clin. Oncol. 16:1998;1574-1581.
23. Sola G.A.R., Arguelles M.G., Bottazzini D.L., Furnari J.C., Parada I.G., Rojo A., Ruiz H.V. Lutetium-177-EDTMP for bone pain palliation. Preparation, biodistribution and pre-clinical studies. Radiochim. Acta. 88:2000;157-161.
24. Srivastava S.C. Therapeutic radionuclides. making the right choice Mather S.J. Current Directions in Radiopharmaceutical Research and Development. 1996;Kluwer Academic Publishers, Dordrecht.
25. Turner J.H., Martindale A.A., Sorby P., Hetherington E.L., Fleay R.F., Hoffman R.F., Claringbold P.G. Samarium-153 EDTMP therapy of disseminated skeletal metastasis. Eur. J. Nucl. Med. 15:1989;784-795.
26. Volkert W.A., Hoffman T.J. Therapeutic radiopharmaceuticals. Chem. Rev. 99:1999;2269-2292.
27. Volkert W.A., Simon J., Ketring A.R., Holmes R.A., Lattimer L.C., Corwin L.A. Radiolabeled Phosphonic Acid chelates. potential therapeutic agents for treatment of skeletal metastases Drugs Future. 14(8):1989;799-811.