CD56: A useful marker for diagnosing Merkel cell carcinoma

Journal of Dermatological Science

Volumn 31, Issue 3, 2003, Pages 219-224

  Kurokawa, Motoki ^a   Nabeshima, Kazuki ^b   Akiyama, Yutaka ^c   Maeda, Shunichi ^a   Nishida, Takaaki ^a   Nakayama, Fumiko ^a   Amano, Masahiro ^a   Ogata, Katsumi ^a   Setoyama, Mitsuru ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b FUKUOKA UNIVERSITY HOSPITAL   (Japan)

^c UNIVERSITY OF MIYAZAKI HOSPITAL   (Japan)

Author keywords

CD56; Immunohistochemical marker; Merkel cell carcinoma; NCAM

Indexed keywords

CD56 ANTIGEN; CD57 ANTIGEN; CHROMOGRANIN A; CYTOKERATIN 20; EPITHELIAL MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; NERVE CELL ADHESION MOLECULE; NEURON SPECIFIC ENOLASE; PARAFFIN; SYNAPTOPHYSIN; TUMOR MARKER;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIVER METASTASIS; LYMPH NODE METASTASIS; MALE; MERKEL CELL TUMOR; NEUROENDOCRINOLOGY; PRIORITY JOURNAL; STAINING;

EID: 0242585371     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-1811(03)00029-X     Document Type: Article

References (15)

1. Scott M.P., Helm K.F. Cytokeratin 20: a marker for diagnosing Merkel cell carcinoma. Am. J. Dermatopathol. 21:1999;16-20.
2. Warner TFCS, Uno H., Hafez G.R., Burgess J., Bolles C., Lloyd R.V., Oka M. Merkel cell and Merkel cell tumors; ultrastructure, immunocytochemistry and review of the literature. Cancer. 52:1983;238-245.
3. Ratner D., Nelson B.R., Brown M.D., Johnson T. Merkel cell carcinomas. J. Am. Acad. Dermatol. 29:1993;143-156.
4. Leech S.N., Kolar A.J.O., Barrett P.D., Sinclair S.A., Leonard N. Merkel cell carcinoma can be distinguished from metastatic small cell carcinoma using antibodies to cytokeratin 20 and thyroid transcription factor 1. J. Clin. Pathol. 54:2001;727-729.
5. Hanly A.J., Elgart G.W., Jorda M., Smith J., Nadji M. Analysis of thyroid transcription factor-1 and cytokeratin 20 separates merkel cell carcinoma from small cell carcinoma of lung. J. Cutan. Pathol. 27:2000;118-120.
6. Wick M.R. Immunohistology of neuroendocrine and neuroectodermal tumors. Semin. Diagn. Pathol. 17:2000;194-203.
7. Seldeslagh K.A., Lauweryns J.M. NCAM expression in the pulmonary neural and diffuse neuroendocrine cell system. Microsc. Res. Tech. 37:1997;69-76.
8. Del Rio M., Demoly P., Koros A.M.C., Laurent J.C., Mani J.C., Pau B., Pujol J.L. JLP5B9: new monoclonal antibody against polysialylated neural cell adhesion molecule is of value in phenotyping lung cancer. J. Immunol. Methods. 233:2000;21-31.
9. Jaques G.J., Auerbach B., Pritsch M., Wolf M., Madry N., Havemann K. Evaluation of serum neural cell adhesion molecule as a new tumor marker in small cell lung cancer. Cancer. 72:1993;418-425.
10. Gallego R., Garcia-Caballero T., Fraga M., Beiras A., Forteza J. Neural cell adhesion molecule immunoreactivity in Merkel cells and Merkel cell tumours. Virchows Arch. 426:1995;317-321.
11. Parrado C., Bjornhagen V., Eusebi V., Falkmer U.G., Hoog A., Garcia-Caballero T., Perez de Vargas I., Falkmer S. Prognosticating tools in primary neuroendocrine (Merkel-cell) carcinomas of the skin: histopathological subdivision, DNA cytometry, cell proliferation analyses (Ki-67-immunoreactivity) and NCAM immunohistochemistry. A clinicopathological study in 25 patients. Pathol. Res. Pract. 194:1998;11-23.
12. Pacinda S.J., Ledet S.C., Gondo M.M., Langston C., Brown R.W., Carmona P.A., Franklin R.B., Roggli V.L., Cagle P.T. p53 and MDM2 immunostaining in pulmonary blastomas and bronchogenic carcinomas. Hum. Pathol. 27:1996;542-546.
13. Nabeshima K., Shimao Y., Sato S., Kataoka H., Moriyama T., Kawano H., Wakisaka S., Koono M. Expression of c-Met correlates with grade of malignancy in human astrocytic tumors: an immunohistochemical study. Histopathology. 31:1997;436-443.
14. Nabeshima K., Shimao Y., Inoue T., Koono M. Immunohistochemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts. Cancer Lett. 176:2002;101-109.
15. Hage R., Elbers H.R., Brutel de la Riviere A., van den Bosch J.M. Neural cell adhesion molecule expression: prognosis in 889 patients with resected non-small cell lung cancer. Chest. 114:1998;1316-1320.