The long-term effect of recombinant tissue-plasminogen-activator (rt-PA) on edema formation in a large-animal model of intracerebral hemorrhage

Neurological Research

Volumn 25, Issue 3, 2003, Pages 254-262

  Thiex, Ruth ^a   Küker, Wilhelm ^a   Müller, Harald D ^a   Rohde, Ina ^a   Schröder, J Michael ^a   Gilsbach, Joachim M ^a   Rohde, Veit ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Brain edema; Fibrinolysis; Intracerebral hemorrhage; Recombinant tissue Plasminogen Activator

Indexed keywords

ALTEPLASE; FIBRINOLYTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPIRATION; BLOOD CLOT LYSIS; BRAIN EDEMA; BRAIN HEMATOMA; BRAIN HEMORRHAGE; CONTROLLED STUDY; DRUG EFFECT; FRONTAL LOBE; GLIA CELL; HEMISPHERE; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; MALE; NERVE CELL NECROSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; SWINE; WHITE MATTER;

ANIMALS; BRAIN; BRAIN EDEMA; CEREBRAL HEMORRHAGE; FIBRINOLYTIC AGENTS; HEMATOMA; MAGNETIC RESONANCE IMAGING; MALE; MODELS, ANIMAL; RECOMBINANT PROTEINS; SUCTION; SWINE; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 0242584828     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164103101201463     Document Type: Article

References (43)

1. Batjer HH, Reisch JS, Allen BC, Plaizier LJ, Su CJ. Failure of surgery to improve outcome in hypertensive putaminal hemorrhage. A prospective randomized trial. Arch Neurol 1990; 47: 1103-1106
2. Juvela S, Heiskanen O, Poranen A, Valtonen S, Knurne T, Kaste M, Troupp H. The treatment of spontaneous intracerebral hemorrhage. A prospective randomized trial of surgical and conservative treatment. J Neurosurg 1989; 70: 755-758
3. McKissock W, Richardson A, Taylor. Primary intracerebral hemorrhage. A controlled trial of surgical and conservative treatment in 180 unselected cases. Lancet 1961; 2: 221-226
4. Waga S, Yamamoto Y. Hypertensive putaminal hemorrhage: Treatment and results. Is surgical treatment superior to conservative one? Stroke 1983; 14: 480-485
5. Wagner KR, Xi G, Hua Y, Kleinholz M, de Courten-Myers GM, Myers RE, Broderick JP, Brott TG. Lobar intracerebral hemorrhage model in pigs: Rapid edema development in perihematomal white matter. Stroke 1996; 27: 490-497
6. Gong C, Boulis N, Qian J, Turner DE, Hoff JT, Keep RF. Intracerebral hemorrhage-induced neuronal death. Neurosurgery 2001; 48: 875-883
7. Lee KR, Betz AL, Kim S, Keep RF, Hoff JT. The role of the coagulation cascade in brain edema formation after intracerebral hemorrhage. Acta Neurochir (Wien) 1996; 138: 396-372
8. Xi G, Keep RF, Hoff JT. Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats. J Neurosurg 1998; 89: 991-996
9. Smirnova IV, Zhang SX, Citron BA, Arnold PM, Festoff BW. Thrombin is an extracellular signal that activates intracellular death protease pathways inducing apoptosis in model motor neurons. J Neurobiol 1998; 36: 64-80
10. Ogihara K, Zubkov AY, Bernanke DH, Lewis AI, Parent AD, Zhang JH. Oxyhemoglobin-induced apoptosis in cultured endothelial cells. J Neurosurg 1999; 91: 459-465
11. Lippitz BE, Mayfrank L, Spetzger U, Warnke JP, Bertalanffy H, Gilsbach JM. Lysis of basal ganglia haematoma with recombinant tissue plasminogen activator (rtPA) after stereotactic aspiration: Initial results. Acta Neurochir (Wien) 1994; 127: 157-160
12. Mohadjer M, Braus DF, Myers A, Scheremet R, Krauss JK. CT-stereotactic fibrinolysis of spontaneous intracerebral hematomas. Neurosurg Rev 1992; 15: 105-110
13. Backlund E, van House M. Controlled subtotal evacuation of intracerebral hematomas by stereotactic technique. Surg Neurol 1978; 9: 99-101
14. Higgins AC, Nashold BS. Stereotactic evacuation of large intracerebral hematomas. Appl Neurophysiol 1980; 43: 96-103
15. Doi E, Moriwaki M, Komai N, Iwamoto M. Stereotactic evacuation of intracerebral hematomas. Neurol Med Chir (Tokyo) 1982; 22: 461-467
16. Matsumoto K, Hondo H. CT-guided stereotaxic evacuation of hypertensive intracerebral hematomas. J Neurosurg 1984; 61: 440-448
17. Kaufman HH, Schochet S, Koss W, Herschberger J, Bernstein D. Efficacy and safety of tissue plasminogen activator. Neurosurgery 1987; 20: 403-407
18. Wang YF, Tsirka SE, Strickland S, Stieg PE, Soriano SG, Lipton SA. Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-ype and tPA-deficient mice. Nat Med 1998; 4: 228-231
19. Tsirka SE, Gualandris A, Amaral DG, Strickland S. Excitotoxin-induced neuronal degeneration and seizure mediated by tissue plasminogen activator. Nature 1995; 377: 340-344
20. Deinsberger W, Vogel J, Kuschinsky W, Auer LM, Böker DK. Experimental intracerebral hemorrhage: Description of a double injection model in rats. Neurol Res 1996; 18: 475-477
21. Küker W, Thiex R, Rohde I, Rohde V, Thron A. Experimental acute intracerebral hemorrhage. Value of MR sequences for a safe diagnosis at 1.5 and 0.5 T. Acta Radiol 2000; 41: 544-552
22. Schaller C, Rohde V, Meyer B, Hassler W. Stereotactic puncture and lysis of spontaneous intracerebral hemorrhage using recombinant tissue-Plasminogen Activator. Neurosurgery 1995; 36: 328-335
23. Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, Khoury J. The ABCs of measuring intracerebral hemorrhage volumes. Stroke 1996; 27: 1304-1305
24. Lee KR, Colon GP, Betz AL, Keep RF, Kim S, Hoff JT. Edema from intracerebral hemorrhage: The role of thrombin. J Neurosurg 1996; 84: 91-96
25. Wakui S, Furusato M, Itoh T, Sasaki H, Akiyama A, Kinoshita I, Asano K, Tokuda T, Aizawa S, Ushigome S. Tumour angiogenesis in prostatic carcinoma with and without bone marrow metastasis: A morphometric study. J Pathol 1992; 168: 257-262
26. Zimmermann RA. Recent advances in MR imaging: FLAIR imaging. Crit Rev Neurosurg 1998; 8: 188-192
27. Rosenberg GA, Navratil M. Metalloproteinase inhibition blocks edema in intracerebral hemorrhage in the rat. Neurology 1997; 48: 921-926
28. Mayfrank L, Lippitz B, Groth M, Bertalanffy H, Gilsbach JM. Effect of recombinant tissue plasminogen activator on clot lysis and ventricular dilatation in the treatment of severe intraventricular hemorrhage. Acta Neurochir (Wien) 1993; 122: 32-38
29. Mayfrank L, Kim Y, Kissler J, Delsing P, Gilsbach JM, Schröder JM, Weis J. Morphological changes following experimental intraventricular haemorrhage and intraventricular fibrinolytic treatment with recombinant tissue plasminogen activator. Acta Neuropathol 2000; 100: 561-567
30. Rohde V, Rohde I, Reinges MH, Mayfrank L, Gilsbach JM. Frameless stereotactically guided catheter placement and fibrinolytic therapy for spontaneous intracerebral hematomas: Technical aspects and initial clinical results. Minim Invasive Neurosurg 2000; 43: 9-17
31. Rohde V, Schaller C, Hassler WE. Intraventricular recombinant tissue plasminogen activator for lysis of intraventricular hemorrhage. J Neurol Neurosurg Psychiatry 1995; 58: 447-51
32. Wagner KR, Xi G, Hua Y, Zuccarello M, de Courten-Myers GM, Broderick JP, Brott TG. Ultra-early clot aspiration after lysis with tissue plasminogen activator in a porcine model of intracerebral hemorrhage: Edema reduction and blood-brain barrier protection. J Neurosurg 1999; 90: 491-498
33. Rosenberg GA, Estrada EY. Atrial natriuretic peptide blocks hemorrhagic brain edema after 4-hour delay in rats. Stroke 1995; 26: 874-877
34. Rosenberg GA, Navratil MJ. (S)-emopamil reduces brain edema from collagenase-induced hemorrhage in rats. Stroke 1994; 25: 2067-2071
35. Rosenberg GA, Scremin O, Strada E, Kyner WT. Arginine vasopressin V1-antagonist and atrial natriuretic peptide reduce hemorrhagic brain edema in rats. Stroke 1992; 23: 1767-1774
36. Nath FP, Kelly PT, Jenkins A, Mendelow AD, Graham DI, Teasdale GM. Effects of experimental intracerebral hemorrhage on blood flow, capillary permeability, and histochemistry. J Neurosurg 1987; 66: 555-562
37. Yang GY, Betz AL, Hoff JT, Chenevert TL, Brunberg JA, Hoff JT. Experimental intracerebral hemorrhage: Relationship between brain edema, blood flow, and blood brain barrier permeability in rats. J Neurosurg 1994; 81: 93-102
38. Figueroa BE, Keep RF, Betz L, Hoff JT. Plasminogen activators potentiate thrombin-induced brain injury. Stroke 1998; 29: 1202-1208
39. Jenkins A, Maxwell WL, Graham DI. Experimental intracerebral haematoma in the rat: Sequential light microscopical changes. Neuropathol Appl Neurobiol 1989; 15: 477-486
40. Enzmann DR, Britt RH, Lyons BE, Buxton JL, Wilson DA. Natural history of experimental intracranial haemorrhage: Sonography, computed tomography and neuropathology. Am J Neurol Radiol 1981; 2: 517-526
41. Takasugi S, Ueda S, Matsumoto K. Chronological changes in spontaneous intracerebral haematoma - an experimental and clinical study. Stroke 1985; 16: 651-658
42. Spatz H. Pathologische Anatomie der Kreislaufstörungen des Gehirns. Z Neurology 1939; 167: 301-351
43. Tsirka SE. Clinical implications of the involvement of tPA in neuronal cell death. J Mol Med 1997; 75: 341-347