Impaired interleukin-1β converting enzyme (ICE) activity in patients with pulmonary tuberculosis

International Journal of Tuberculosis and Lung Disease

Volumn 7, Issue 11, 2003, Pages 1109-1112

  Fujiuchi, Satoru ^a,b   Matsumoto, H ^a   Yamazaki, Y ^a   Nakata, H ^a   Takahashi, M ^a   Nakao, S ^a   Takeda, A ^a   Okamoto, K ^a   Fujita, Y ^a   Fujikane, T ^a   Shimizu, T ^a  

^a National Dohoku Hospital   (Japan)

^b Dohoku National Hospital   (Japan)

Author keywords

ICE; IL 18; Tuberculosis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 18; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LUNG TUBERCULOSIS; MONOCYTE; MONONUCLEAR CELL; PRIORITY JOURNAL; BIOSYNTHESIS; BLOOD; CELL CULTURE; ENZYMOLOGY; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CASPASE 1; CELLS, CULTURED; HUMANS; INTERFERON TYPE II; INTERLEUKIN-18; LEUKOCYTES, MONONUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUBERCULOSIS, PULMONARY;

EID: 0242583975     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Okamura H, Tsutsui H, Komatsu T. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 1995; 378: 88-91.
2. Tone M, Thompson S A, Tone Y, Fairchild P J, Waldman H. Regulation of IL-18 (IFN-γ inducing factor) gene expression. J Immunol 1997; 159: 6156-6163.
3. Gu Y, Kuida K, Tsutsui H, et al. Activation of interferon-γ -inducing factor mediated by interleukin-1β converting enzyme. Science 1997; 275: 206-209.
4. Ghayur T, Banerjee S, Hugunin M, et al. Caspase 1 processes IFN-γ-inducing factor and regulates LPS-induced IFN-γ production. Nature 1997: 386: 619-623.
5. Yamada G, Shijubo N, Shigehara K, Okamura H, Kurimoto M, Abe S. Increased levels of circulating interleukin-18 in patients with advanced tuberculosis. Am J Respir Crit Care Med 2000; 161: 1786-1789.
6. Ushio S, Namba M, Okura T, et al. Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol 1996, 156: 4274-4279.
7. Munder M, Mallo M, Eichmann K, Modolell M. Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophage activation. J Exp Med 1998; 187: 2103-2108.
8. Pizarro T T, Michie M H, Bentz M, et al. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells. J Immunol 1999; 162: 6829-6835.
9. Shigehara K, Shijubo N, Ohmichi M, et al. IL-12 and IL-18 are increased and stimulate IFN-gamma production in sarcoid lungs. J Immunol 2001; 166: 642-649.
10. Zhang M, Lin Y, Iyer D V, Gong J, Abrams J S, Barnes P F. T-cell cytokine responses in human infection with Mycobacterium tuberculosis. Infect Immun 1995; 63: 3231-3234.
11. Vanham G, Toossi Z, Hirsch C S, et al. Examining a paradox in the pathogenesis of human pulmonary tuberculosis: immune activation and suppression/anergy. Tubercle Lung Dis 1997; 78: 145-158.
12. McAlindon M E, Hawkey C J, Mahida Y R. Expression of interleukin 1 beta and interleukin 1 beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease. Gut 1998; 42: 214-219.