Preoperative Irradiation for Prevention of Heterotopic Ossification Following Prosthetic Total Hip Replacement: Results of a Prospective Study in 462 Hips

Strahlentherapie und Onkologie

Volumn 179, Issue 11, 2003, Pages 767-773

  Koelbl, Oliver ^b   Seufert, Julia ^c   Pohl, Fabian ^c   Tauscher, Annette ^a   Lehmann, Harald ^a   Springorum, Hans Werner ^a   Flentje, Michael ^c  

^a CARITAS KRANKENHAUS   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c NONE

Author keywords

Eterotopic ossification; Nonsteroidal anti inflammatory drugs; Preoperative radiotherapy; Total hip arthroplasty

Indexed keywords

ANTIBIOTIC AGENT; DICLOFENAC; DIPYRONE; NONSTEROID ANTIINFLAMMATORY AGENT; TRAMADOL;

ADULT; AGED; ANALGESIA; ANTIBIOTIC THERAPY; ARTICLE; BODY HEIGHT; DISEASE SEVERITY; FEMALE; GENDER; HETEROTOPIC OSSIFICATION; HIP RADIOGRAPHY; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PREOPERATIVE RADIOTHERAPY; RISK FACTOR; SCORING SYSTEM; TOTAL HIP PROSTHESIS; TREATMENT INDICATION;

ADULT; AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHROPLASTY, REPLACEMENT, HIP; CHI-SQUARE DISTRIBUTION; DICLOFENAC; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OBESITY; OSSIFICATION, HETEROTOPIC; OSTEOARTHRITIS; PREOPERATIVE CARE; PROSPECTIVE STUDIES; RADIOTHERAPY; RADIOTHERAPY DOSAGE; RISK FACTORS; TIME FACTORS;

EID: 0242583852     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00066-003-1088-y     Document Type: Article

References (50)

1. Ahrengart L, Lindgren U. Heterotopic bone after hip arthroplasty. Defining the patient at risk. Clin Orthop 1993;293:153-9.
2. Arcq M. Ectopic ossification: a complication after total hip replacement. Arch Orthop Unfallchir 1973;77:108-31.
3. Brooker AF, Bowerman JW, Robinson RA, et al. Ectopic ossification following total hip replacement. Incidence and method of classification. J Bone Joint Surg Am 1973;55:1629-32.
4. Bundrick TJ, Cook DE, Resnik CS. Heterotopic bone formation in patients with DISH following total hip replacement. Radiology 1985;155:595-7.
5. Coventry MB, Scanlon PW. The use of radiation to discourage ectopic bone. J Bone Joint Surg Am 1981;63:201-8.
6. Dahl HK. Klinske observasjoner In: Blindern MSD, ed. Symposium on arthrose. Drammen/Norway, 1975:37-46.
7. DeLee J, Ferrari A, Charnley J. Ectopic bone formation following low friction arthroplasty of the hip. Clin Orthop 1976;121:53-9.
8. Duck HJ, Mylod A Jr. Heterotopic bone in hip arthroplasties. Cemented versus noncemented. Clin Orthop 1992;282:145-53.
9. Eggli S, Woo A. Risk factors for heterotopic ossification in total hip arthroplasty. Arch Orthop Trauma Surg 2001;121:531-5.
10. Goel A, Sharp DJ. Heterotopic bone formation after hip replacement. The influence of the type of osteoarthritis. J Bone Joint Surg Am 1991;73:255-7.
11. Goutallier D, Colmar M, Penot P. Periprosthetic ossifications of the hip. Role of the duration of postoperative indomethacin therapy in the preventation of ossifications and role of scremed acetabulum in the occurrence of ossification. Rev Chir Orthop Reparatrice Appar Mot 1993;79:22-8.
12. Gregoritch SJ, Chadha M, Pelligrini VD, et al. Randomized trial comparing preoperative versus postoperative irradiation for prevention of heterotopic ossification following prothetic total hip replacement. Preliminary results. Int J Radiat Oncol Biol Phys 1994;30:55-62.
13. Ham AW, Cormack DH. Ectopic osteogenesis. In: Ham AW, Cormack DH, eds. Histology, 8th edn. Phyladelphia: Lippincott, 1979:393-4.
14. Hartwig CH, Sell S, Kusswetter W. Periarticular ossification following cement-free and cement-fixed total endoprosthesis implantation in the hip joint. Z Orthop Ihre Grenzgeb 1989;127:296-301.
15. Hedley AK, Mead LP, Hendren DH. The prevention of heterotopic bone formation following total hip arthroplasty using 600 rad in a single dose. J Arthroplasty 1989;4:319-25.
16. Heyd R, Schopohl B, Kirchner J, et al. Preoperative radiotherapy for prevention of heterotopic ossifications after hip endoprosthesis. Akt Radiol 1997;7:270-3.
17. Hierton C, Blomgren G, Lindgren U. Factors associated with heterotopic bone formation in cemened otal hip prostheses. Acta Orthop Scand 1983;53:698-702.
18. Jockheck M, Willms R, Volkmann R, et al. Prevention of periarticular heterotopic ossification after endoprosthetic hipjoint replacement by means of diclofenac. Arch Orthop Trauma Surg 1998;117:337-40.
19. Kantorowitz DA, Miller GJ, Ferrara JA, et al. Preoperative versus postoperative irradiation in the prophylaxis of heterotopic bone formation in rats. Int J Radiat Oncol Biol Phys 1990;19:1431-8.
20. Kantorowitz DA, Muff NS. Preoperative versus postoperative irradiation in the prophylaxis of heterotopic ossification: a rural community hospital's experience. Int J Radiat Oncol Biol Phys 1998;40:171-6.
21. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957;16:494-502.
22. Kienapfet H, Koller M, Wüst A, et al. Prevention of heterotopic bone formation after total hip arthroplasty. A prospective randomised study comparing postoperative radiation therapy with indomethacin medication. Arch Orthop Trauma Surg 1999;119:296-302.
23. Kjaersgaard AP, Hougard K, Linde F, et al. Heterotopic bone formation after total hip arthroplasty in patients with primary or secondary coxarthrosis. Orthopedics 1990;13:1211-7.
24. Kölbl O, Flentje M, Eulert J, et al. Prospective study on the prevention of heterotopic ossification after total hip replacement. Non-steroidal anti-inflammatory agents versus radiation therapy. Strahlenther Onkol 1997;173:677-82.
25. Koelbl O, Knaus P, Pohl F, et al. Radiation-induced reduction of BMP-induced proteoglycan synthesis in an embryonal mesenchymal tissue equivalent using the chicken "limb bud" test. Strahlenther Onkol 2001;177:432-6.
26. Kölbl O, Knelles D, Barthel T, et al. Randomized trial comparing early postoperative irradiation versus the use of non-steroidal-antiinflammatory drugs for prevention of heterotopic ossification following prosthetic total hip replacement. Int J Radiat Oncol Biol Phys 1997;39:961-6.
27. Kölbl O, Knelles D, Barthel T, et al. Preoperative irradiation versus the use of nonsteroidal anti-inflammatory drugs for prevention of heterotopic ossification following total hip replacement. The results of a randomized trial. Int J Radiat Oncol Biol Phys 1998;42:397-401.
28. Konski A, Pellegrini V, Poulter C, et al. Randomized trial comparing single dose versus fractionated irradiation for prevention of heterotopic bone: aa preliminary report. Int J Radiat Oncol Biol Phys 1990;18:1139-42.
29. Lazansky MG. Complications revisited - the debit side of total hip replacement. Clin Orthop 1973;95:96-103.
30. Lo TCM, Healy WL, Covall DJ, et al. Heterotopic bone formation after hip surgery: prevention with single-dose postoperative hip irradiation. Radiology 1988;168:851-4.
31. Lonardi F, Giogna G, Coeli M, et al. Preoperative, single-fraction irradiation for prophylaxis of heterotopic ossification after total hip arthroplasty. Int Orthop 2001;25:371-4.
32. MacLennan I, Keys HM, Evarts CM, et al. Usefulness of postoperative hip irradiation in the prevention of heterotopic bone formation in a high risk group of patients. Int J Radiat Oncol Biol Phys 1984;10:49-53.
33. Maloney WJ, Krushell RJ, Jasty M, et al. Incidence of heterotopic ossification after total hip replacement: effect of the type of fixation of the femoral component. J Bone Joint Surg Am 1991;73:191-3.
34. McMahon JS, Waddell JP, Morton J. Effect of short-course indomethacin on heterotopic bone formation after uncemented total hip arthroplasty. J Arthroplasty 1991;6:259-64.
35. Morrey BF, Adams RA, Cabanela ME. Comparison of heterotopic bone after anterolateral, transtrochanteric, and posterior approaches for total hip arthroplasty. Clin Orthop 1984;188:160-7.
36. Nollen JG, van Douveren FQ. Ectopic ossification in hip arthroplasty. A retrospective study of predisposing factors in 637 cases. Acta Orthop Scand 1993;64:185-7.
37. Owen M. Lineage of osteogenic cells and their relationship to the stromal system In: Peck WA, ed. Bone and mineral research, vol 3. New York: Elsevier Science, 1985:1-25.
38. Pellegrini VD, Gregoritch SJ. Preoperative irradiation for prevention of heterotopic ossification following total hip arthroplasty. J Bone Joint Surg Am 1996;78:870-81.
39. Rosendahl S, Christoffersen JK, Norgaard M. Paraarticular ossifications following hip replacement. Acta Orthop Scand 1977;48:400-4.
40. Rudicel S. Paraartikuläre ektopische oder heterotope Ossifikationen nach Hüfttotalprothese. Orthopäde 1985;14:54-7.
41. Sauer R, Seegenschmiedt MH, Goldmann A, et al. Prevention of periarticular ossification following endoprosthetic hip replacement using postoperative irradiation. Strahlenther Onkol 1992;168:89-99.
42. Sautter-Bihl ML, Hultenschmidt B, Liebermeister E, et al. Fractionated and single-dose radiotherapy for heterotopic bone formation in patients with spinal cord injury. A phase-I/II study. Strahlenther Onkol 2001;177:200-5.
43. Seegenschmiedt MH, Keilholz L, Martus P, et al. Prevention of heterotopic ossification about the hip: final results of two randomized trials in 410 patients using either preoperative or postoperative radiation therapy. Int J Radiat Oncol Biol Phys 1997;39:161-71.
44. Seegenschmiedt MH, Makoski HB, Micke O. Radiation prophylaxis for heterotopic ossification about the hip joint - a multicenter study. Int J Radiat Oncol Biol Phys 2001;51:756-65.
45. Seegenschmiedt MH, Martus P, Goldmann AR, et al. [Pre- and postoperative radiotherapy to prevent heterotopic ossification of the hip joint.] Strahlenther Onkol 1994;170:281-91.
46. Seegenschmiedt MH, Martus P, Goldmann AR, et al. Preoperative versus postoperative radiotherapy for prevention of heterotopic ossification HO. First results of a randomized trial in high-risk patients. Int J Radiat Oncol Biol Phys 1994;30:63-73.
47. Sundaram NA, Murphy JC. Heterotopic bone formation following total hip arthroplasty in ankylosing spondylitis. Clin Orthop 1986;207:223-6.
48. Testa NN, Mazur KU. Heterotopic ossification after direct lateral approach and transtrochanteric approach to the hip. Orthop Rev 1988;17:965-71.
49. Van der Heide HJ, Koorevaar RT, Schreurs BW, et al. Indomethacin for 3 days is not effective as prophylaxis for heterotopic ossification after primary total hip arthroplasty. J Arthroplasty 1999;14:796-9.
50. Van Leeuwen WM, Deckers P, De Lange WJ. Preoperative irradiation for prophylaxis of ectopic ossification after hip arthroplasty. A randomised study in 62 hips. Acta Orthop Scand 1998;69:116-8.