Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate

Urology

Volumn 62, Issue 5, 2003, Pages 942-946

  Shibata, Yasuhiro ^a   Ono, Yoshihiro ^b   Kashiwagi, Bunzo ^b   Suzuki, Kazuhiro ^b   Fukabori, Yoshitatsu ^b   Honma, Seijiro ^b   Yamanaka, Hidetoshi ^b  

^a GUNMA UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIANDROGEN; BICALUTAMIDE; CHLORMADINONE ACETATE; FINASTERIDE; FLUTAMIDE; TAMSULOSIN; TERAZOSIN;

ALPHA ADRENERGIC RECEPTOR BLOCKING; ANDROGEN BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; BLEEDING TENDENCY; BLOOD SAMPLING; CAPILLARY PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; HISTOLOGY; HORMONAL REGULATION; HORMONE ACTION; MALE; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT;

EID: 0242580056     PISSN: 00904295     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-4295(03)00566-1     Document Type: Article

References (16)

1. Rittmaster R.S., Norman R.W., Thomas L.N., et al. Evidence for atrophy and apoptosis in the prostates of men given finasteride. J Clin Endocrinol Metab. 81:1996;814-819.
2. Shabsigh A., Chang D.T., Heitjan D.F., et al. Rapid reduction in blood flow to the rat ventral prostate gland after castration preliminary evidence that androgens influence prostate size by regulating blood flow to the prostate gland and prostatic endothelial cell survival. Prostate. 36:1998;201-206.
3. Lekas E., Bergh A., Damber J.E. Effects of finasteride and bicalutamide on prostatic blood flow in the rat. BJU Int. 85:2000;962-965.
4. Shibata Y., Ito K., Suzuki K., et al. Changes in the endocrine environment of the human prostate transition zone with aging simultaneous quantitative analysis of prostatic sex steroids and comparison with human prostatic histological composition. Prostate. 42:2000;45-55.
5. Shibata Y., Fukabori Y., Ito K., et al. Comparison of histological compositions and apoptosis in canine spontaneous benign prostatic hyperplasia treated with androgen suppressive agents chlormadinone acetate and finasteride. J Urol. 165:2001;289-293.
6. Heymann M.A., Payne B.D., Hoffman J.I., et al. Blood flow measurements with radionuclide-labeled particles. Prog Cardiovasc Dis. 20:1977;55-79.
7. Selstam G., Damber J.E. Measurement of blood flow to the ventral prostate in the rat with radioactive microspheres effects of estradiol-17 beta and human chorionic gonadotrophin. Acta Physiol Scand. 119:1983;209-212.
8. Shabisgh A., Tanji N., D'Agati V., et al. Early effects of castration on the vascular system of the rat ventral prostate gland. Endocrinology. 140:1999;1920-1926.
9. Lekas E., Johansson M., Widmark A., et al. Decrement of blood flow precedes the involution of the ventral prostate in the rat after castration. Urol Res. 25:1997;309-314.
10. Perimenis P., Gyftopoulos K., Markou S., et al. Effects of finasteride and cyproterone acetate on hematuria associated with benign prostatic hyperplasia a prospective, randomized, controlled study. Urology. 59:2002;373-377.
11. Delakas D., Lianos E., Karyotis I., et al. Finasteride a long-term follow-up in the treatment of recurrent hematuriaassociated with benign prostatic hyperplasia. Urol Int. 67:2001;69-72.
12. Sandfeldt L., Bailey D.M., Hahn R.G. Blood loss during transurethral resection of the prostate after 3 months of treatment with finasteride. Urology. 58:2001;972-976.
13. Sieber P.R., Rommel F.M., Huffnagle H.W., et al. The treatment of gross hematuria secondary to prostatic bleeding with finasteride. J Urol. 159:1998;1232-1233.
14. Miller M.I., Puchner P.J. Effects of finasteride on hematuria associated with benign prostatic hyperplasia long-term follow-up. Urology. 51:1998;237-240.
15. Carlin B.I., Bodner D.R., Spirnak J.P., et al. Role of finasteride in the treatment of recurrent hematuria secondary to benign prostatic hyperplasia. Prostate. 31:1997;180-182.
16. Hagerty J.A., Ginsberg P.C., Harmon J.D., et al. Pretreatment with finasteride decreases perioperative bleeding associated with transurethral resection of the prostate. Urology. 55:2000;684-689.