Benzodiazepine Use and Physical Performance in Community-Dwelling Older Women

Journal of the American Geriatrics Society

Volumn 51, Issue 11, 2003, Pages 1563-1570

  Gray, Shelly L ^a   Penninx, Brenda W J H ^b   Blough, David K ^h   Artz, Margaret B ^c   Guralnik, Jack M ^d   Wallace, Robert B ^e   Buchner, Dave M ^f   LaCroix, Andrea Z ^a,g  

^a UNIVERSITY OF WASHINGTON   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d NATIONAL INSTITUTE ON AGING   (United States)

^e UNIVERSITY OF IOWA   (United States)

^f NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION   (United States)

^g CENTER FOR HEALTH STUDIES   (United States)

^h Box 357630 ^*

Author keywords

Activities of daily living; Aged; Benzodiazepine; Cohort studies

Indexed keywords

ALPRAZOLAM; BENZODIAZEPINE DERIVATIVE; CHLORDIAZEPOXIDE; CLONAZEPAM; CLORAZEPATE; DIAZEPAM; FLURAZEPAM; LORAZEPAM; OXAZEPAM; TEMAZEPAM; TRIAZOLAM;

ARTICLE; DAILY LIFE ACTIVITY; DRUG USE; FEMALE; FOLLOW UP; HUMAN; INTERVIEW; MAJOR CLINICAL STUDY; PHYSICAL PERFORMANCE; RISK ASSESSMENT; SCORING SYSTEM; STANDING; WALKING SPEED;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; ANXIETY; BENZODIAZEPINES; COHORT STUDIES; COMPUTER GRAPHICS; FEMALE; GERIATRIC ASSESSMENT; HUMANS; LINEAR MODELS; MOTOR ACTIVITY; PHYSICAL FITNESS; PROSPECTIVE STUDIES;

EID: 0242576049     PISSN: 00028614     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1532-5415.2003.51502.x     Document Type: Article

References (40)

1. Gleason PP, Schutz R, Smith NL et al. Correlates and prevalence of benzodiazepine use in community-dwelling elderly. J Gen Intern Med 1998;13:243-250.
2. Blazer D, Hybels C, Simonsick E et al. Sedative, hypnotic, and antianxiety medication use in an aging cohort over ten years: A racial comparison. J Am Geriatr Soc 2000;48:1073-1079.
3. Mayer-Oakes SA, Kelman G, Beers MH et al. Benzodiazepine use in older, community-dwelling southern Californians. Prevalence and clinical correlates. Ann Pharmacother 1993;27:416-421.
4. Leipzig RM, Cumming RG, Tinetti ME. Drugs and falls in older people: A systematic review and meta-analysis: I. Psychotropic drugs. J Am Geriatr Soc 1999;47:30-39.
5. Herings RM, Stricker BH, de Boer A et al. Benzodiazepines and the risk of falling leading to femur fractures. Dosage more important than elimination half-life. Arch Intern Med 1995;155:1801-1807.
6. Ray WA, Griffin MR, Downey W. Benzodiazepines of long and short elimination half-life and the risk of hip fracture. JAMA 1989;262:3303-3307.
7. Patten SB, Williams JV, Love EJ. Self-reported depressive symptoms following treatment with corticosteroids and sedative-hypnotics. Int J Psychiatry Med 1996;26:15-24.
8. Hanlon JT, Horner RD, Schmader KE et al. Benzodiazepine use and cognitive function among community-dwelling elderly. Clin Pharmacol Ther 1998;64:684-692.
9. Ried LD, Johnson RE, Gettman DA. Benzodiazepine exposure and functional status in older people. J Am Geriatr Soc 1998;46:71-76.
10. Sarkisian CA, Liu H, Gutierrez PR et al. Modifiable risk factors predict functional decline among older women: A prospectively validated clinical prediction tool. The Study of Osteoporotic Fractures Research Group. J Am Geriatr Soc 2000;48:170-178.
11. Gray SL, LaCroix AZ, Blough D et al. Is the use of benzodiazepines associated with incident disability? J Am Geriatr Soc 2002;50:1012-1018.
12. Guralnik JM, Fried LP, Salive ME. Disability as a public health outcome in the aging population. Annu Rev Public Health 1996;17:25-46.
13. Guralnik JM, Simonsick EM, Ferrucci L et al. A short physical performance battery assessing lower extremity function. Association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994;49:M85-M94.
14. Guralnik JM, Ferrucci L, Simonsick EM et al. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med 1995;332:556-561.
15. Penninx BW, Ferrucci L, Leveille SG et al. Lower extremity performance in nondisabled older persons as a predictor of subsequent hospitalization. J Gerontol A Biol Sci Med Sci 2000;55A:M691-M697.
16. Cornoni-Huntley J, Ostfeld AM, Taylor JO et al. Established populations for epidemiologic studies of the elderly: Study design and methodology. Aging (Milano) 1993;5:27-37.
17. Helling DK, Lemke JH, Semla TP et al. Medication use characteristics in the elderly: The Iowa 65+ Rural Health Study. J Am Geriatr Soc 1987;35:4-12.
18. Kastrup EK, ed. Facts and Comparisons, 2000. St Louis: Facts and Comparisons, 2000.
19. Winograd CH, Lemsky CM, Nevitt MC et al. Development of a physical performance and mobility examination. J Am Geriatr Soc 1994;42:743-749.
20. Seeman TE, Charpentier PA, Berkman LF et al. Predicting changes in physical performance in a high-functioning elderly cohort. MacArthur studies of successful aging. J Geronrol 1994;49:M97-M108.
21. Nevitt MC, Cummings SR, Kidd S et al. Risk factors for recurrent nonsyncopal falls. A prospective study. JAMA 1989;261:2663-2668.
22. World Health Organization. Manual of the International Statistical Classification of Diseases, Injuries, and Causes of Death. Geneva, Switzerland: World Health Organization, 1977.
23. Rose GA. The diagnosis of ischaemic heart pain and intermittent claudication in field surveys. Bull WHO 1962;27:645-658.
24. Rosow I, Breslau N. A Guttman health scale for the aged. J Gerontol 1966;21:556-559.
25. Katz S, Downs TD, Cash HR et al. Progress in development of the index of ADL. Gerontologist 1970;10:20-30.
26. Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Meas 1977;1:385-401.
27. Kohout FJ, Berkman LF, Evans DA et al. Two shorter forms of the CES-D (Center for Epidemiological Studies Depression) depression symptoms index. J Aging Health 1993;5:179-193.
28. Beekman AT, Deeg DJ, Van Limbeek J et al. Criterion validity of the Center for Epidemiologic Studies Depression scale (CES-D): Results from a community-based sample of older subjects in The Netherlands. Psychol Med 1997;27:231-235.
29. Lyness JM, Noel TK, Cox C et al. Screening for depression in elderly primary care patients. A comparison of the Center for Epidemiologic Studies-Depression Scale and the Geriatric Depression Scale. Arch Intern Med 1997;157:449-454.
30. Pfeiffer E. A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. J Am Geriatr Soc 1975;23:433-441.
31. Little RJA, Rubin DB. Statistical Analysis with Missing Data. New York: John Wiley and Sons, 1987.
32. Penninx BW, Guralnik JM, Ferrucci L et al. Depressive symptoms and physical decline in community-dwelling older persons. JAMA 1998;279:1720-1726.
33. Olfson M, Pincus HA. Use of benzodiazepines in the community. Arch Intern Med 1994;154:1235-1240.
34. Penninx BW, Leveille S, Ferrucci L et al. Exploring the effect of depression on physical disability: Longitudinal evidence from the established populations for epidemiologic studies of the elderly. Am J Public Health 1999;89:1346-1352.
35. Tinetti ME, Inouye SK, Gill TM et al. Shared risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes. JAMA 1995;273:1348-1353.
36. Pearson JL. Summary of a National Institute of Mental Health workshop on late-life anxiety. Psychopharmacol Bull 1998;34:127-130.
37. Lenze EJ, Rogets JC, Martire LM et al. The association of late-life depression and anxiety with physical disability: A review of the literature and prospectus for future research. Am J Geriatr Psychiatry 2001;9:113-135.
38. Mohler H, Fritschy JM, Rudolph U. A new benzodiazepine pharmacology. J Pharmacol Exp Ther 2002;300:2-8.
39. Braestrup C, Nielsen M. Benzodiazepine receptors. In: Iversen LL, Iversen SD, Snyder SH, eds. Biochemical Studies of CNS Receptors. New York: Plenum Press, 1983, pp 285-384.
40. Cutson TM, Gray SL, Hughes MA et al. Effect of a single dose of diazepam on balance measures in older people. J Am Geriatr Soc 1997;45:435-440.