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Volumn 33, Issue 11, 2003, Pages 988-997

New concepts in bilirubin encephalopathy

Author keywords

Bilirubin; Encephalopathy; Jaundice; Kernicterus; Neonates; Nuerotoxicity

Indexed keywords

ABC TRANSPORTER; ALBUMIN; BILIRUBIN; CARBROMAL; GLUTATHIONE TRANSFERASE; NEUROTRANSMITTER; ORGANIC ANION TRANSPORTER; WATER;

EID: 0242552895     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2003.01261.x     Document Type: Review
Times cited : (131)

References (149)
  • 1
    • 0030629822 scopus 로고    scopus 로고
    • Bilirubin metabolism and kernicterus
    • Gourley GR. Bilirubin metabolism and kernicterus. Adv Pediatr 1997;44:173-229.
    • (1997) Adv Pediatr , vol.44 , pp. 173-229
    • Gourley, G.R.1
  • 3
    • 0036688934 scopus 로고    scopus 로고
    • Evidence for carrier-mediated transport of unconjugated bilirubin across plasma membrane vesicles from human placental trophoblast
    • Serrano MA, Bayón JE, Pascolo L, Tiribelli C, Ostrow JD, Gonzalez-Gallego J et al. Evidence for carrier-mediated transport of unconjugated bilirubin across plasma membrane vesicles from human placental trophoblast. Placenta 2002;23:527-35.
    • (2002) Placenta , vol.23 , pp. 527-535
    • Serrano, M.A.1    Bayón, J.E.2    Pascolo, L.3    Tiribelli, C.4    Ostrow, J.D.5    Gonzalez-Gallego, J.6
  • 6
    • 0038541723 scopus 로고    scopus 로고
    • Intestinal colonization leading to fecal urobilinoid excretion may play a role in the pathogenesis of neonatal jaundice
    • Vítek L, Kotal P, Jirsa M, Malina J, Cerna M, Chmelar D et al. Intestinal colonization leading to fecal urobilinoid excretion may play a role in the pathogenesis of neonatal jaundice. J Pediatr Gastroenterol Nutr 2000;30:294-8.
    • (2000) J Pediatr Gastroenterol Nutr , vol.30 , pp. 294-298
    • Vítek, L.1    Kotal, P.2    Jirsa, M.3    Malina, J.4    Cerna, M.5    Chmelar, D.6
  • 7
    • 0025150585 scopus 로고
    • Antioxidant activities of bile pigments: Iliverdin and bilirubin
    • Stocker R, McDonagh AF, Glazer AN, Ames BN. Antioxidant activities of bile pigments: iliverdin and bilirubin. Meth Enzymol 1990;186:301-9.
    • (1990) Meth Enzymol , vol.186 , pp. 301-309
    • Stocker, R.1    McDonagh, A.F.2    Glazer, A.N.3    Ames, B.N.4
  • 8
    • 0033515043 scopus 로고    scopus 로고
    • Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury
    • Dore S, Takahashi M, Ferris CD, Zakhary R, Hester LD, Guastella D et al. Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury. Proc Natl Acad Sci USA 1999;96:2445-50.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2445-2450
    • Dore, S.1    Takahashi, M.2    Ferris, C.D.3    Zakhary, R.4    Hester, L.D.5    Guastella, D.6
  • 9
    • 0033374730 scopus 로고    scopus 로고
    • Neuroprotective action of bilirubin against oxidative stress in primary hippocampal cultures
    • Dore S, Snyder SH. Neuroprotective action of bilirubin against oxidative stress in primary hippocampal cultures. Ann N Y Acad Sci 1999;890:167-72.
    • (1999) Ann N Y Acad Sci , vol.890 , pp. 167-172
    • Dore, S.1    Snyder, S.H.2
  • 10
    • 0022577995 scopus 로고
    • Breast milk jaundice in the newborn. A real entity
    • Schneider AP. Breast milk jaundice in the newborn. A real entity. JAMA 1986;255:3270-4.
    • (1986) JAMA , vol.255 , pp. 3270-3274
    • Schneider, A.P.1
  • 11
    • 0030691028 scopus 로고    scopus 로고
    • Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: A dose-dependent genetic interaction crucial to neonatal hyperbilirubinaemia
    • Kaplan M, Renbaum P, Levy-Lahad E, Hammerman C, Lahad A, Beutler E. Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: a dose-dependent genetic interaction crucial to neonatal hyperbilirubinaemia. Proc Natl Acad Sci USA 1997;94:12128-32.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12128-12132
    • Kaplan, M.1    Renbaum, P.2    Levy-Lahad, E.3    Hammerman, C.4    Lahad, A.5    Beutler, E.6
  • 13
    • 0020418654 scopus 로고
    • Serum bilirubin levels in breast- and formula-fed infants in the first 5 days of life
    • Saigal S, Lunyk O, Bennett KJ, Patterson MC. Serum bilirubin levels in breast-and formula-fed infants in the first 5 days of life. Can Med Assoc J 1982;127:985-9.
    • (1982) Can Med Assoc J , vol.127 , pp. 985-989
    • Saigal, S.1    Lunyk, O.2    Bennett, K.J.3    Patterson, M.C.4
  • 14
    • 0029121161 scopus 로고
    • Kernicterus in otherwise healthy, breast-fed term newborns
    • Maisels MJ, Newman TB. Kernicterus in otherwise healthy, breast-fed term newborns. Pediatrics 1995;96:730-3.
    • (1995) Pediatrics , vol.96 , pp. 730-733
    • Maisels, M.J.1    Newman, T.B.2
  • 15
    • 0035055199 scopus 로고    scopus 로고
    • Interaction of coding region mutations and the Gilbert-type promoter abnormality of the UGT1A1 gene causes moderate degrees of unconjugated hyperbilirubinaemia and may lead to neonatal kernicterus
    • Kadakol A, Sappal BS, Ghosh SS, Lowenheim M, Chowdhury A, Chowdhury S et al. Interaction of coding region mutations and the Gilbert-type promoter abnormality of the UGT1A1 gene causes moderate degrees of unconjugated hyperbilirubinaemia and may lead to neonatal kernicterus. J Med Genet 2001;38:244-9.
    • (2001) J Med Genet , vol.38 , pp. 244-249
    • Kadakol, A.1    Sappal, B.S.2    Ghosh, S.S.3    Lowenheim, M.4    Chowdhury, A.5    Chowdhury, S.6
  • 16
    • 0033510908 scopus 로고    scopus 로고
    • Gilbert's syndrome is a contributory factor in prolonged unconjugated hyperbilirubinaemia of the newborn
    • Monaghan G, McLellan A, McGeehan A, Li VS, Mollica F, Salemi I et al. Gilbert's syndrome is a contributory factor in prolonged unconjugated hyperbilirubinaemia of the newborn. J Pediatr 1999;134:441-6.
    • (1999) J Pediatr , vol.134 , pp. 441-446
    • Monaghan, G.1    McLellan, A.2    McGeehan, A.3    Li, V.S.4    Mollica, F.5    Salemi, I.6
  • 17
    • 0036305499 scopus 로고    scopus 로고
    • Glucose-6-phosphate dehydrogenase deficiency, the UDP-glucuronosyl transferase 1A1 gene, and neonatal hyperbilirubinaemia
    • Huang CS, Chang PF, Huang MJ, Chen ES, Chen WC. Glucose-6-phosphate dehydrogenase deficiency, the UDP-glucuronosyl transferase 1A1 gene, and neonatal hyperbilirubinaemia. Gastroenterology 2002;123:127-33.
    • (2002) Gastroenterology , vol.123 , pp. 127-133
    • Huang, C.S.1    Chang, P.F.2    Huang, M.J.3    Chen, E.S.4    Chen, W.C.5
  • 18
    • 0019860388 scopus 로고
    • The prenatal and postnatal development of UDP-glucuronyltransferase activity towards bilirubin and the effect of premature birth on this activity in the human liver
    • Kawade N, Onishi S. The prenatal and postnatal development of UDP-glucuronyltransferase activity towards bilirubin and the effect of premature birth on this activity in the human liver. Biochem J 1981;196:257-60.
    • (1981) Biochem J , vol.196 , pp. 257-260
    • Kawade, N.1    Onishi, S.2
  • 19
    • 0025345701 scopus 로고
    • Behavioral changes correlated with brain-stem auditory evoked responses in term infants with moderate hyperbilirubinaemia
    • Vohr BR, Karp D, O'Dea C, Darrow D, Coll CG, Lester BM et al. Behavioral changes correlated with brain-stem auditory evoked responses in term infants with moderate hyperbilirubinaemia [see comments]. J Pediatr 1990;117:288-91.
    • (1990) J Pediatr , vol.117 , pp. 288-291
    • Vohr, B.R.1    Karp, D.2    O'Dea, C.3    Darrow, D.4    Coll, C.G.5    Lester, B.M.6
  • 20
    • 0033950424 scopus 로고    scopus 로고
    • The blood-brain barrier and bilirubin encephalopathy
    • Wennberg RP. The blood-brain barrier and bilirubin encephalopathy. Cell Mol Neurobiol 2000;20:97-109.
    • (2000) Cell Mol Neurobiol , vol.20 , pp. 97-109
    • Wennberg, R.P.1
  • 21
    • 0025289989 scopus 로고
    • Clinical features of bilirubin encephalopathy
    • Connolly AM, Volpe JJ. Clinical features of bilirubin encephalopathy. Clin Perinatol 1990;17:371-9.
    • (1990) Clin Perinatol , vol.17 , pp. 371-379
    • Connolly, A.M.1    Volpe, J.J.2
  • 22
    • 0002354917 scopus 로고
    • Bilirubin and brain injury
    • Volpe JJ, editor. Philadelphia: W.B. Saunders
    • Volpe JJ. Bilirubin and brain injury. In: Volpe JJ, editor. Neurology and the Newborn. Philadelphia: W.B. Saunders;1995.pp. 490-514.
    • (1995) Neurology and the Newborn , pp. 490-514
    • Volpe, J.J.1
  • 23
    • 0001065901 scopus 로고
    • The late clinical syndrome of posticteric encephalopathy
    • Perlstein MA. The late clinical syndrome of posticteric encephalopathy. Pediatr Clin N Am 1960;7:665-87.
    • (1960) Pediatr Clin N Am , vol.7 , pp. 665-687
    • Perlstein, M.A.1
  • 24
    • 0000528240 scopus 로고
    • Kernicterus
    • Bruyn VP, Bruyn GW, editors. Amsterdam: North-Holland
    • Larroche JC. Kernicterus. In: Bruyn VP, Bruyn GW, editors. Handbook of Clinical Neurology. Amsterdam: North-Holland; 1968.pp. 491-515.
    • (1968) Handbook of Clinical Neurology , pp. 491-515
    • Larroche, J.C.1
  • 25
    • 0031807941 scopus 로고    scopus 로고
    • Jaundice in full-term and near-term babies who leave the hospital within 36 hours. The pediatrician's nemesis
    • Maisels MJ, Newman TB. Jaundice in full-term and near-term babies who leave the hospital within 36 hours. The pediatrician's nemesis. Clin Perinatol 1998;25:295-302.
    • (1998) Clin Perinatol , vol.25 , pp. 295-302
    • Maisels, M.J.1    Newman, T.B.2
  • 26
    • 0036264612 scopus 로고    scopus 로고
    • System-based approach to management of neonatal jaundice and prevention of kernicterus
    • Johnson LH, Bhutani VK, Brown AK. System-based approach to management of neonatal jaundice and prevention of kernicterus. J Pediatr 2002;140:396-403.
    • (2002) J Pediatr , vol.140 , pp. 396-403
    • Johnson, L.H.1    Bhutani, V.K.2    Brown, A.K.3
  • 27
    • 0033751406 scopus 로고    scopus 로고
    • Kernicterus in term and near-term infants - The specter walks again
    • Hansen TW. Kernicterus in term and near-term infants - the specter walks again. Acta Paediatr 2000;89:1155-7.
    • (2000) Acta Paediatr , vol.89 , pp. 1155-1157
    • Hansen, T.W.1
  • 28
    • 0018812596 scopus 로고
    • Binding of bilirubin to albumin; implications for prevention of bilirubin encephalopathy in the newborn
    • Brodersen R. Binding of bilirubin to albumin; implications for prevention of bilirubin encephalopathy in the newborn. CRC Crit Rev Clin Lab Sci 1979;11:305-99.
    • (1979) CRC Crit Rev Clin Lab Sci , vol.11 , pp. 305-399
    • Brodersen, R.1
  • 29
    • 0001863821 scopus 로고
    • The role of albumin binding in hepatic organic anion transport
    • Tavoloni N, Berk PD, editors. New York: Raven Press
    • Weisiger RA. The role of albumin binding in hepatic organic anion transport. In: Tavoloni N, Berk PD, editors. Hepatic Transport and Bile Secretion; Physiology and Pathphysiology. New York: Raven Press;1993.pp. 171-96.
    • (1993) Hepatic Transport and Bile Secretion; Physiology and Pathphysiology , pp. 171-196
    • Weisiger, R.A.1
  • 30
    • 0035687247 scopus 로고    scopus 로고
    • Bilirubin-albumin binding and free bilirubin
    • Ahlfors CE. Bilirubin-albumin binding and free bilirubin. J Perinatol 2001;21 (Suppl. 1):S40-S42.
    • (2001) J Perinatol , vol.21 , Issue.1 SUPPL.
    • Ahlfors, C.E.1
  • 32
    • 0242482969 scopus 로고
    • Haemolytic disease of the newborn
    • Gardner K, editor. London: J.A. Churchill Ltd.
    • Mollison PL, Cutbush M. Haemolytic disease of the newborn. In: Gardner K, editor. Recent Advances in Pediatrics. London: J.A. Churchill Ltd.;1954.pp. 10-32.
    • (1954) Recent Advances in Pediatrics , pp. 10-32
    • Mollison, P.L.1    Cutbush, M.2
  • 33
    • 0035683929 scopus 로고    scopus 로고
    • Jaundice technologies: Prediction of hyperbilirubinaemia in term and near-term newborns
    • Bhutani VK, Johnson LH. Jaundice technologies: prediction of hyperbilirubinaemia in term and near-term newborns. J Perinatol 2001;21 (Suppl. 1):S76-S82.
    • (2001) J Perinatol , vol.21 , Issue.1 SUPPL.
    • Bhutani, V.K.1    Johnson, L.H.2
  • 34
    • 0028110519 scopus 로고
    • Structure and binding of unconjugated bilirubin: Relevance for physiological and pathophysiological function
    • Ostrow JD, Mukerjee P, Tiribelli C. Structure and binding of unconjugated bilirubin: relevance for physiological and pathophysiological function. J Lipid Res 1994;35:1715-37.
    • (1994) J Lipid Res , vol.35 , pp. 1715-1737
    • Ostrow, J.D.1    Mukerjee, P.2    Tiribelli, C.3
  • 35
    • 0033574696 scopus 로고    scopus 로고
    • Unconjugated bilirubin exhibits spontaneous diffusion through model lipid bilayers and native hepatocyte membranes
    • Zucker SD, Goessling W, Hoppin AG. Unconjugated bilirubin exhibits spontaneous diffusion through model lipid bilayers and native hepatocyte membranes. J Biol Chem 1999;274:10852-62.
    • (1999) J Biol Chem , vol.274 , pp. 10852-10862
    • Zucker, S.D.1    Goessling, W.2    Hoppin, A.G.3
  • 36
    • 0014108489 scopus 로고
    • Bilirubin encephalopathy in the Gunn rat: A fine structure study of the cerebellar cortex
    • Schutta HS, Johnson LH. Bilirubin encephalopathy in the Gunn rat: a fine structure study of the cerebellar cortex. J Neuropathol Exp Neurol 1967;26:377-96.
    • (1967) J Neuropathol Exp Neurol , vol.26 , pp. 377-396
    • Schutta, H.S.1    Johnson, L.H.2
  • 37
    • 0001846916 scopus 로고
    • Pathogenesis of kernicterus in the light of its sequelae
    • Swinyard CA, editor. Springfield, IL: Charles C. Thomas
    • Malamud N. Pathogenesis of kernicterus in the light of its sequelae. In: Swinyard CA, editor. Kernicterus and its Importance in Cerebral Palsy. Springfield, IL: Charles C. Thomas;1961.pp. 230-46.
    • (1961) Kernicterus and Its Importance in Cerebral Palsy , pp. 230-246
    • Malamud, N.1
  • 38
    • 0021321793 scopus 로고
    • The neuropathology of kernicterus in the premature neonate: Diagnostic problems
    • Ahdab-Barmada M, Moossy J. The neuropathology of kernicterus in the premature neonate: diagnostic problems. J Neuropathol Exp Neurol 1984;43:45-56.
    • (1984) J Neuropathol Exp Neurol , vol.43 , pp. 45-56
    • Ahdab-Barmada, M.1    Moossy, J.2
  • 40
    • 0027571990 scopus 로고
    • Cerebellar hypoplasia in the hyperbilirubinemic Gunn rat: Morphological aspects
    • Yamamura H, Takagishi Y. Cerebellar hypoplasia in the hyperbilirubinemic Gunn rat: morphological aspects. Nagoya J Med Sci 1993;55:11-21.
    • (1993) Nagoya J Med Sci , vol.55 , pp. 11-21
    • Yamamura, H.1    Takagishi, Y.2
  • 41
    • 0017072598 scopus 로고
    • Developmental features of cerebellar hypoplasia and brain bilirubin levels in a mutant (Gunn) rat with hereditary hyperbilirubinaemia
    • Sawasaki Y, Yamada N, Nakajima H. Developmental features of cerebellar hypoplasia and brain bilirubin levels in a mutant (Gunn) rat with hereditary hyperbilirubinaemia. J Neurochem 1976;27:577-83.
    • (1976) J Neurochem , vol.27 , pp. 577-583
    • Sawasaki, Y.1    Yamada, N.2    Nakajima, H.3
  • 42
    • 0030903507 scopus 로고    scopus 로고
    • Development of cerebellar hypoplasia in jaundiced Gunn rats: A quantitative light microscopic analysis
    • Berl
    • Conlee JW, Shapiro SM. Development of cerebellar hypoplasia in jaundiced Gunn rats: a quantitative light microscopic analysis. Acta Neuropathol (Berl) 1997;93:450-60.
    • (1997) Acta Neuropathol , vol.93 , pp. 450-460
    • Conlee, J.W.1    Shapiro, S.M.2
  • 43
    • 0018377332 scopus 로고
    • CNS changes in hyperbilirubinaemia. Functional implications
    • Jew JY, Sandquist D. CNS changes in hyperbilirubinaemia. Functional implications. Arch Neurol 1979;36:149-54.
    • (1979) Arch Neurol , vol.36 , pp. 149-154
    • Jew, J.Y.1    Sandquist, D.2
  • 44
    • 0035075564 scopus 로고    scopus 로고
    • New concepts in bilirubin neurotoxicity and the need for studies at clinically relevant bilirubin concentrations
    • Ostrow JD, Tiribelli C. Editorial: New concepts in bilirubin neurotoxicity and the need for studies at clinically relevant bilirubin concentrations. J Hepatol 2001;34:467-70.
    • (2001) J Hepatol , vol.34 , pp. 467-470
    • Ostrow, J.D.1    Tiribelli, C.2
  • 45
    • 0036234687 scopus 로고    scopus 로고
    • Mechanisms of bilirubin neurotoxicity
    • Ostrow JD, Pascolo L, Tiribelli C. Editorial: Mechanisms of bilirubin neurotoxicity. Hepatology 2002;35:1277-80.
    • (2002) Hepatology , vol.35 , pp. 1277-1280
    • Ostrow, J.D.1    Pascolo, L.2    Tiribelli, C.3
  • 46
    • 0038647817 scopus 로고    scopus 로고
    • Reassessment of the unbound concentrations of unconjugated bilirubin in relation to neurotoxicity in vitro
    • Ostrow JD, Pascolo L, Tiribelli C. Reassessment of the unbound concentrations of unconjugated bilirubin in relation to neurotoxicity in vitro. Pediatr Res 2003;54:98-104.
    • (2003) Pediatr Res , vol.54 , pp. 98-104
    • Ostrow, J.D.1    Pascolo, L.2    Tiribelli, C.3
  • 47
    • 0026761329 scopus 로고
    • Ionization and self association of unconjugated bilirubin, determined by rapid solvent partition from chloroform, with further studies of bilirubin solubility
    • Hahm JS, Ostrow JD, Mukerjee P, Celic L. Ionization and self association of unconjugated bilirubin, determined by rapid solvent partition from chloroform, with further studies of bilirubin solubility. J Lipid Res 1992;33:1123-37.
    • (1992) J Lipid Res , vol.33 , pp. 1123-1137
    • Hahm, J.S.1    Ostrow, J.D.2    Mukerjee, P.3    Celic, L.4
  • 49
    • 0035655285 scopus 로고    scopus 로고
    • Localization of bilirubin in phospholipid bilayers by parallax analysis of fluorescence quenching
    • Zucker SD, Goessling W, Bootle EJ, Sterritt C. Localization of bilirubin in phospholipid bilayers by parallax analysis of fluorescence quenching. J Lipid Res 2001;42:1377-88.
    • (2001) J Lipid Res , vol.42 , pp. 1377-1388
    • Zucker, S.D.1    Goessling, W.2    Bootle, E.J.3    Sterritt, C.4
  • 50
    • 0030607714 scopus 로고    scopus 로고
    • Cytotoxicity of bilirubin for human fibroblasts and rat astrocytes in culture. Effect of the ratio of bilirubin to serum albumin
    • Chuniaud L, Dessante M, Chantoux F, Blondeau JP, Francon J, Trivin F. Cytotoxicity of bilirubin for human fibroblasts and rat astrocytes in culture. Effect of the ratio of bilirubin to serum albumin. Clin Chim Acta 1996;256:103-14.
    • (1996) Clin Chim Acta , vol.256 , pp. 103-114
    • Chuniaud, L.1    Dessante, M.2    Chantoux, F.3    Blondeau, J.P.4    Francon, J.5    Trivin, F.6
  • 51
    • 0033547349 scopus 로고    scopus 로고
    • Inhibition of glutamate uptake by unconjugated bilirubin in cultured rat astrocytes: Role of concentration and pH
    • Silva RFM, Mata LR, Gulbenkian S, Brito A, Tiribelli C, Brites D. Inhibition of glutamate uptake by unconjugated bilirubin in cultured rat astrocytes: Role of concentration and pH. Biochem Biophys Res Commun 1999;265:67-72.
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 67-72
    • Silva, R.F.M.1    Mata, L.R.2    Gulbenkian, S.3    Brito, A.4    Tiribelli, C.5    Brites, D.6
  • 52
    • 0021955905 scopus 로고
    • Bilirubin toxicity in neural cell lines N115 and NBR10A
    • Schiff D, Chan G, Poznansky MJ. Bilirubin toxicity in neural cell lines N115 and NBR10A. Pediatr Res 1985;19:908-11.
    • (1985) Pediatr Res , vol.19 , pp. 908-911
    • Schiff, D.1    Chan, G.2    Poznansky, M.J.3
  • 53
    • 0033669937 scopus 로고    scopus 로고
    • Bilirubin induces apoptosis via activation of NMDA receptors in developing rat brain neurons
    • Grojean S, Koziel V, Vert P, Daval JL. Bilirubin induces apoptosis via activation of NMDA receptors in developing rat brain neurons. Exp Neurol 2000;166:334-41.
    • (2000) Exp Neurol , vol.166 , pp. 334-341
    • Grojean, S.1    Koziel, V.2    Vert, P.3    Daval, J.L.4
  • 54
    • 0035072101 scopus 로고    scopus 로고
    • Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid
    • Silva RFM, Rodrigues CMP, Brites D. Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid. J Hepatol 2001;34:402-8.
    • (2001) J Hepatol , vol.34 , pp. 402-408
    • Silva, R.F.M.1    Rodrigues, C.M.P.2    Brites, D.3
  • 55
    • 0036238782 scopus 로고    scopus 로고
    • Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons
    • Rodrigues CMP, Sola S, Brites D. Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons. Hepatology 2002;35:1186-95.
    • (2002) Hepatology , vol.35 , pp. 1186-1195
    • Rodrigues, C.M.P.1    Sola, S.2    Brites, D.3
  • 56
    • 0015147490 scopus 로고
    • 14C between blood, cerebrospinal fluid, and brain tissue
    • 14C between blood, cerebrospinal fluid, and brain tissue. Am J Physiol 1971;221:1264-70.
    • (1971) Am J Physiol , vol.221 , pp. 1264-1270
    • Rodriguez Garay, E.A.1    Scremin, O.U.2
  • 57
    • 0001130357 scopus 로고
    • Hereditary acholuric jaundice in a new mutant strain of rats
    • Gunn CK. Hereditary acholuric jaundice in a new mutant strain of rats. J Hered 1938;29:137-9.
    • (1938) J Hered , vol.29 , pp. 137-139
    • Gunn, C.K.1
  • 58
    • 0001526339 scopus 로고
    • Kernicterus in rats with an inherited deficiency of glucuronyl transferase
    • Johnson LH, Sarmiento F, Blanc WA, Day R. Kernicterus in rats with an inherited deficiency of glucuronyl transferase. Am J Dis Child 1959;97:591-608.
    • (1959) Am J Dis Child , vol.97 , pp. 591-608
    • Johnson, L.H.1    Sarmiento, F.2    Blanc, W.A.3    Day, R.4
  • 59
  • 60
    • 0001328751 scopus 로고
    • Bilirubin uridine diphosphoglucuronyltransferase in rat liver microsomes. Genetic variation and maturation
    • Strebel L, Odell GB. Bilirubin uridine diphosphoglucuronyltransferase in rat liver microsomes. genetic variation and maturation. Pediatr Res 1971;5:548-59.
    • (1971) Pediatr Res , vol.5 , pp. 548-559
    • Strebel, L.1    Odell, G.B.2
  • 61
    • 0014627334 scopus 로고
    • Clinical signs and morphologic abnormalities in Gunn rats treated with sulfadimethoxine
    • Schutta HS, Johnson LH. Clinical signs and morphologic abnormalities in Gunn rats treated with sulfadimethoxine. J Pediatr 1969;75:1070-9.
    • (1969) J Pediatr , vol.75 , pp. 1070-1079
    • Schutta, H.S.1    Johnson, L.H.2
  • 62
    • 0020074623 scopus 로고
    • Learning deficits and brain monoamines in rats with congenital hyperbilirubinaemia
    • Swenson RM, Jew JY. Learning deficits and brain monoamines in rats with congenital hyperbilirubinaemia. Exp Neurol 1982;76:447-56.
    • (1982) Exp Neurol , vol.76 , pp. 447-456
    • Swenson, R.M.1    Jew, J.Y.2
  • 63
    • 0023883824 scopus 로고
    • Development of brainstem auditory evoked potentials in heterozygous and homozygous jaundiced Gunn rats
    • Shapiro SM, Hecox KE. Development of brainstem auditory evoked potentials in heterozygous and homozygous jaundiced Gunn rats. Brain Res 1988;469:147-57.
    • (1988) Brain Res , vol.469 , pp. 147-157
    • Shapiro, S.M.1    Hecox, K.E.2
  • 64
    • 0023851753 scopus 로고
    • Acute brainstem auditory evoked potential abnormalities in jaundiced Gunn rats given sulfonamide
    • Shapiro SM. Acute brainstem auditory evoked potential abnormalities in jaundiced Gunn rats given sulfonamide. Pediatr Res 1988;23:306-10.
    • (1988) Pediatr Res , vol.23 , pp. 306-310
    • Shapiro, S.M.1
  • 65
    • 0026042859 scopus 로고
    • Brainstem auditory evoked potentials correlate with morphological changes in Gunn rat pups
    • Shapiro SM, Conlee JW. Brainstem auditory evoked potentials correlate with morphological changes in Gunn rat pups. Hear Res 1991;57:16-22.
    • (1991) Hear Res , vol.57 , pp. 16-22
    • Shapiro, S.M.1    Conlee, J.W.2
  • 66
    • 0025984416 scopus 로고
    • Morphological changes in the cochlear nucleus and nucleus of the trapezoid body in Gunn rat pups
    • Conlee JW, Shapiro SM. Morphological changes in the cochlear nucleus and nucleus of the trapezoid body in Gunn rat pups. Hear Res 1991;57:23-30.
    • (1991) Hear Res , vol.57 , pp. 23-30
    • Conlee, J.W.1    Shapiro, S.M.2
  • 67
    • 0013911111 scopus 로고
    • 14C into the central nervous system
    • 14C into the central nervous system. J Clin Invest 1966;45:678-89.
    • (1966) J Clin Invest , vol.45 , pp. 678-689
    • Diamond, I.1    Schmid, R.2
  • 68
    • 0014817386 scopus 로고
    • The distribution and toxicity of bilirubin. E. Mead Johnson address 1969
    • Odell GB. The distribution and toxicity of bilirubin. E. Mead Johnson address 1969. Pediatrics 1970;46:16-24.
    • (1970) Pediatrics , vol.46 , pp. 16-24
    • Odell, G.B.1
  • 69
    • 0018342130 scopus 로고
    • Acute bilirubin encephalopathy induced with sulfadimethoxine in Gunn rats
    • Rose AL, Wisniewski H. Acute bilirubin encephalopathy induced with sulfadimethoxine in Gunn rats. J Neuropathol Exp Neurol 1979;38:152-64.
    • (1979) J Neuropathol Exp Neurol , vol.38 , pp. 152-164
    • Rose, A.L.1    Wisniewski, H.2
  • 72
    • 0002767421 scopus 로고
    • Physical chemistry of bile pigments and porphyrins with particular reference to bile
    • Ostrow JD, editor. New York: Marcel Dekker
    • Carey MC, Spivak W. Physical chemistry of bile pigments and porphyrins with particular reference to bile. In: Ostrow JD, editor. Bile Pigments and Jaundice; Molecular, Metabolic and Medical Aspects. New York: Marcel Dekker;1986.pp. 81-132.
    • (1986) Bile Pigments and Jaundice; Molecular, Metabolic and Medical Aspects , pp. 81-132
    • Carey, M.C.1    Spivak, W.2
  • 73
    • 0018791450 scopus 로고
    • Binding to egg phosphatidylcholine of some organic anions (bromsulphophthalein, oestrone sulphate, haem and bilirubin) that bind to ligandin and aminoazo-dye binding protein A
    • Tipping E, Ketterer B, Christodoulides L. Binding to egg phosphatidylcholine of some organic anions (bromsulphophthalein, oestrone sulphate, haem and bilirubin) that bind to ligandin and aminoazo-dye binding protein A. Biochem J 1979;180:327-37.
    • (1979) Biochem J , vol.180 , pp. 327-337
    • Tipping, E.1    Ketterer, B.2    Christodoulides, L.3
  • 74
    • 0033951150 scopus 로고    scopus 로고
    • Mechanism of hepatocellular uptake of albumin-bound bilirubin
    • Zucker SD, Goessling W. Mechanism of hepatocellular uptake of albumin-bound bilirubin. Biochim Biophys Acta 2000;1463:197-208.
    • (2000) Biochim Biophys Acta , vol.1463 , pp. 197-208
    • Zucker, S.D.1    Goessling, W.2
  • 75
    • 0008956686 scopus 로고    scopus 로고
    • Maximum binding capacity of serum albumin for bilirubin is one, as revealed by circular dichroism
    • Siam M, Blaha G, Lehner H. Maximum binding capacity of serum albumin for bilirubin is one, as revealed by circular dichroism. J Chem Soc Perkin Trans II 1998:853-6.
    • (1998) J Chem Soc Perkin Trans II , pp. 853-856
    • Siam, M.1    Blaha, G.2    Lehner, H.3
  • 77
    • 0034653971 scopus 로고    scopus 로고
    • Measurement of plasma unbound unconjugated bilirubin
    • Ahlfors CE. Measurement of plasma unbound unconjugated bilirubin. Anal Biochem 2000;279:130-5.
    • (2000) Anal Biochem , vol.279 , pp. 130-135
    • Ahlfors, C.E.1
  • 78
    • 0035839649 scopus 로고    scopus 로고
    • Affinity of human serum albumin for bilirubin varies with albumin concentration and buffer composition: Results of a novel ultrafiltration method
    • Weisiger RA, Ostrow JD, Koehler RK, Webster CC, Mukerjee P, Pascolo L et al. Affinity of human serum albumin for bilirubin varies with albumin concentration and buffer composition: results of a novel ultrafiltration method. J Biol Chem 2001;276:29953-60.
    • (2001) J Biol Chem , vol.276 , pp. 29953-29960
    • Weisiger, R.A.1    Ostrow, J.D.2    Koehler, R.K.3    Webster, C.C.4    Mukerjee, P.5    Pascolo, L.6
  • 79
    • 0023829746 scopus 로고
    • Structural and functional differences between fetal and adult serum albumin
    • Jori G, Reddi E, Rubaltelli FF. Structural and functional differences between fetal and adult serum albumin. Intl J Pept Protein Res 1988;31:17-21.
    • (1988) Intl J Pept Protein Res , vol.31 , pp. 17-21
    • Jori, G.1    Reddi, E.2    Rubaltelli, F.F.3
  • 80
    • 0026345412 scopus 로고
    • Bilirubin displacing effect of drugs used in neonatology
    • Robertson A, Karp W, Brodersen R. Bilirubin displacing effect of drugs used in neonatology. Acta Paediatr Scand 1991;80:1119-27.
    • (1991) Acta Paediatr Scand , vol.80 , pp. 1119-1127
    • Robertson, A.1    Karp, W.2    Brodersen, R.3
  • 82
    • 0021746883 scopus 로고
    • Penetration of bilirubin into the brain of albumin-deficient and jaundiced rats (AJR) and Nagase analbuminemic rats
    • Tokyo
    • Takahashi M, Sugiyama K, Shumiya S, Nagase S. Penetration of bilirubin into the brain of albumin-deficient and jaundiced rats (AJR) and Nagase analbuminemic rats. J Biochem (Tokyo) 1984;96:1705-12.
    • (1984) J Biochem , vol.96 , pp. 1705-1712
    • Takahashi, M.1    Sugiyama, K.2    Shumiya, S.3    Nagase, S.4
  • 83
    • 0002931546 scopus 로고
    • Aqueous solubility, albumin binding and tissue distribution of bilirubin
    • Ostrow JD, editor. New York: Marcel Dekker
    • Brodersen R. Aqueous solubility, albumin binding and tissue distribution of bilirubin. In: Ostrow JD, editor. Bile Pigments and Jaundice; Molecular, Metabolic and Medical Aspects. New York: Marcel Dekker;1986.pp. 157-81.
    • (1986) Bile Pigments and Jaundice; Molecular, Metabolic and Medical Aspects , pp. 157-181
    • Brodersen, R.1
  • 84
    • 0021240165 scopus 로고
    • Effect of acidosis on bilirubin deposition in rat brain
    • Bratlid D, Cashore WJ, Oh W. Effect of acidosis on bilirubin deposition in rat brain. Pediatrics 1984;73:431-4.
    • (1984) Pediatrics , vol.73 , pp. 431-434
    • Bratlid, D.1    Cashore, W.J.2    Oh, W.3
  • 85
    • 0022625722 scopus 로고
    • Changes in the auditory brainstem response associated with intravenous infusion ofunconjugated bilirubin into infant rhesus monkeys
    • Ahlfors CE, Bennett SH, Shoemaker CT, Ellis WG, Davis SL, Wennberg RP et al. Changes in the auditory brainstem response associated with intravenous infusion ofunconjugated bilirubin into infant rhesus monkeys. Pediatr Res 1986;20:511-5.
    • (1986) Pediatr Res , vol.20 , pp. 511-515
    • Ahlfors, C.E.1    Bennett, S.H.2    Shoemaker, C.T.3    Ellis, W.G.4    Davis, S.L.5    Wennberg, R.P.6
  • 87
    • 0037059054 scopus 로고    scopus 로고
    • From the Cover: Biliverdin reductase: A major physiologic cytoprotectant
    • Barañano DE, Rao M, Ferris CD, Snyder SH. From the Cover: Biliverdin reductase: a major physiologic cytoprotectant. Proc Natl Acad Sci USA 2002;99:16093-8.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16093-16098
    • Barañano, D.E.1    Rao, M.2    Ferris, C.D.3    Snyder, S.H.4
  • 88
    • 0033948974 scopus 로고    scopus 로고
    • Choroid plexus in the central nervous system: Biology and physiopathology
    • Strazielle N, Ghersi-Egea JF. Choroid plexus in the central nervous system: biology and physiopathology. J Neuropathol Exp Neurol 2000;59:561-74.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 561-574
    • Strazielle, N.1    Ghersi-Egea, J.F.2
  • 89
    • 50449153155 scopus 로고
    • Jaundice and xanthochromia of the spinal fluid
    • Berman LB, Lapham LW, Pastore E. Jaundice and xanthochromia of the spinal fluid. J Lab Clin Med 1944;44:273-9.
    • (1944) J Lab Clin Med , vol.44 , pp. 273-279
    • Berman, L.B.1    Lapham, L.W.2    Pastore, E.3
  • 90
    • 0242434083 scopus 로고
    • Bilirubin and protein in the cerebrospinal fluid of jaundiced patients with severe liver disease with and without hepatic coma
    • Amatuzio DS, Weber LJ, Nesbitt S. Bilirubin and protein in the cerebrospinal fluid of jaundiced patients with severe liver disease with and without hepatic coma. J Lab Clin Med 1953;41:615-8.
    • (1953) J Lab Clin Med , vol.41 , pp. 615-618
    • Amatuzio, D.S.1    Weber, L.J.2    Nesbitt, S.3
  • 93
    • 0001234229 scopus 로고    scopus 로고
    • Arachnoid membrane, subarachnoid CSF and pia-glia
    • Pardridge WM, editor. Cambridge UK: Cambridge University Press
    • Johanson CE. Arachnoid membrane, subarachnoid CSF and pia-glia. In: Pardridge WM, editor. Introduction to the Blood-Brain Barrier; Methodology, Biology and Pathology. Cambridge UK: Cambridge University Press;1998. pp. 259-69.
    • (1998) Introduction to the Blood-Brain Barrier; Methodology, Biology and Pathology , pp. 259-269
    • Johanson, C.E.1
  • 94
    • 0035157642 scopus 로고    scopus 로고
    • Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus
    • Ghersi-Egea JF, Strazielle N. Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus. Microsc Res Tech 2001;52:83-8.
    • (2001) Microsc Res Tech , vol.52 , pp. 83-88
    • Ghersi-Egea, J.F.1    Strazielle, N.2
  • 96
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian abc transporters in health and disease
    • Borst P, Oude Elferink R. Mammalian abc transporters in health and disease. Annu Rev Biochem 2002;71:537-92.
    • (2002) Annu Rev Biochem , vol.71 , pp. 537-592
    • Borst, P.1    Oude Elferink, R.2
  • 97
    • 0034214069 scopus 로고    scopus 로고
    • Functional expression of P-glycoprotein and multidrug resistance-associated protein (Mrp1) in primary cultures of rat astrocytes
    • Decleves X, Regina A, Laplanche JL, Roux F, Boval B, Launay JM et al. Functional expression of P-glycoprotein and multidrug resistance-associated protein (Mrp1) in primary cultures of rat astrocytes. J Neurosci Res 2000;60:594-601.
    • (2000) J Neurosci Res , vol.60 , pp. 594-601
    • Decleves, X.1    Regina, A.2    Laplanche, J.L.3    Roux, F.4    Boval, B.5    Launay, J.M.6
  • 98
    • 0033616684 scopus 로고    scopus 로고
    • Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood- Cerebrospinal-fluid drug-permeability barrier
    • Rao VV, Dahlheimer JL, Bardgett ME, Snyder AZ, Finch RA, Sartorelli AC et al. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal- fluid drug-permeability barrier. Proc Natl Acad Sci USA 1999;96:3900-5.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3900-3905
    • Rao, V.V.1    Dahlheimer, J.L.2    Bardgett, M.E.3    Snyder, A.Z.4    Finch, R.A.5    Sartorelli, A.C.6
  • 99
    • 0031724003 scopus 로고    scopus 로고
    • Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells
    • Regina A, Koman A, Piciorti M, El Hafny B, Center MS, Bergmann R et al. Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells. J Neurochem 1998;71:705-15.
    • (1998) J Neurochem , vol.71 , pp. 705-715
    • Regina, A.1    Koman, A.2    Piciorti, M.3    El Hafny, B.4    Center, M.S.5    Bergmann, R.6
  • 100
    • 0036325998 scopus 로고    scopus 로고
    • Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurones
    • Hirrlinger J, Konig J, Dringen R. Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurones. J Neurochem 2002;82:716-9.
    • (2002) J Neurochem , vol.82 , pp. 716-719
    • Hirrlinger, J.1    Konig, J.2    Dringen, R.3
  • 102
    • 0033975098 scopus 로고    scopus 로고
    • Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier
    • Wijnholds J, de Lange EC, Scheffer GL, van den Berg DJ, Mol CA, van der Valk MA et al. Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier. J Clin Invest 2000;105:279-85.
    • (2000) J Clin Invest , vol.105 , pp. 279-285
    • Wijnholds, J.1    De Lange, E.C.2    Scheffer, G.L.3    Van Den Berg, D.J.4    Mol, C.A.5    Van Der Valk, M.A.6
  • 103
    • 0031809205 scopus 로고    scopus 로고
    • Characterization of efflux transport of organic anions in a mouse brain capillary endothelial cell line
    • Kusuhara H, Suzuki H, Naito M, Tsuruo T, Sugiyama Y. Characterization of efflux transport of organic anions in a mouse brain capillary endothelial cell line. J Pharmacol Exp Ther 1998;285:1260-5.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 1260-1265
    • Kusuhara, H.1    Suzuki, H.2    Naito, M.3    Tsuruo, T.4    Sugiyama, Y.5
  • 104
    • 0034116574 scopus 로고    scopus 로고
    • The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae
    • Petrovic S, Pascolo L, Gallo R, Cupelli F, Ostrow JD, Goffeau A et al. The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 2000;16:561-71.
    • (2000) Yeast , vol.16 , pp. 561-571
    • Petrovic, S.1    Pascolo, L.2    Gallo, R.3    Cupelli, F.4    Ostrow, J.D.5    Goffeau, A.6
  • 105
    • 0031891475 scopus 로고    scopus 로고
    • Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates
    • Seetharaman S, Barrand MA, Maskell L, Scheper RJ. Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates. J Neurochem 1998;70:1151-9.
    • (1998) J Neurochem , vol.70 , pp. 1151-1159
    • Seetharaman, S.1    Barrand, M.A.2    Maskell, L.3    Scheper, R.J.4
  • 106
    • 0033961896 scopus 로고    scopus 로고
    • Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain
    • Golden PL, Pardridge WM. Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain. Cell Mol Neurobiol 2000;20:165-81.
    • (2000) Cell Mol Neurobiol , vol.20 , pp. 165-181
    • Golden, P.L.1    Pardridge, W.M.2
  • 108
    • 0031742968 scopus 로고    scopus 로고
    • Brain bilirubin content is increased in P-glycoprotein-deficient transgenic null mutant mice
    • Watchko JF, Daood MJ, Hansen TWR. Brain bilirubin content is increased in P-glycoprotein-deficient transgenic null mutant mice. Pediatr Res 1998;44:763-6.
    • (1998) Pediatr Res , vol.44 , pp. 763-766
    • Watchko, J.F.1    Daood, M.J.2    Hansen, T.W.R.3
  • 109
    • 0242517562 scopus 로고    scopus 로고
    • Inhibition of human MDR1 P-glycoprotein increases bilirubin-induced cell apoptosis in vitro.
    • Abstract
    • Watchko JF, Ziegler J, Daood MJ, Balkundi D. Inhibition of human MDR1 P-glycoprotein increases bilirubin-induced cell apoptosis in vitro. (Abstract) Pediatr Res 2003;53:400A.
    • (2003) Pediatr Res , vol.53
    • Watchko, J.F.1    Ziegler, J.2    Daood, M.J.3    Balkundi, D.4
  • 110
    • 0033178980 scopus 로고    scopus 로고
    • Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics
    • Strazielle N, Ghersi-Egea JF. Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics. J Neurosci 1999;19:6275-89.
    • (1999) J Neurosci , vol.19 , pp. 6275-6289
    • Strazielle, N.1    Ghersi-Egea, J.F.2
  • 111
    • 0035154679 scopus 로고    scopus 로고
    • Organic anion transport across the choroid plexus
    • Gao B, Meier PJ. Organic anion transport across the choroid plexus. Microsc Res Tech 2001;52:60-4.
    • (2001) Microsc Res Tech , vol.52 , pp. 60-64
    • Gao, B.1    Meier, P.J.2
  • 112
    • 0032967070 scopus 로고    scopus 로고
    • Transepithelial transport of organic anions across the choroid plexus: Possible involvement of organic anion transporter and multidrug resistance-associated protein
    • Nishino J, Suzuki H, Sugiyama D, Kitazawa T, Ito K, Hanano M et al. Transepithelial transport of organic anions across the choroid plexus: possible involvement of organic anion transporter and multidrug resistance-associated protein. J Pharmacol Exp Ther 1999;290:289-94.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 289-294
    • Nishino, J.1    Suzuki, H.2    Sugiyama, D.3    Kitazawa, T.4    Ito, K.5    Hanano, M.6
  • 113
    • 0035971239 scopus 로고    scopus 로고
    • Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6
    • Cui Y, Konig J, Leier I, Buchholz U, Keppler D. Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. J Biol Chem 2001;276:9626-30.
    • (2001) J Biol Chem , vol.276 , pp. 9626-9630
    • Cui, Y.1    Konig, J.2    Leier, I.3    Buchholz, U.4    Keppler, D.5
  • 114
    • 0037907742 scopus 로고    scopus 로고
    • Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin
    • Briz O, Serrano MA, Macias RI, Gonzalez-Gallego J, Marin JJ. Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin. Biochem J 2003;371:897-905.
    • (2003) Biochem J , vol.371 , pp. 897-905
    • Briz, O.1    Serrano, M.A.2    Macias, R.I.3    Gonzalez-Gallego, J.4    Marin, J.J.5
  • 115
    • 0038081033 scopus 로고    scopus 로고
    • The Human Organic Anion Transport Protein SLC21A6 Is Not Sufficient for Bilirubin Transport
    • Wang P, Kim RB, Roy Chowdhury R, Wolkoff AW. The Human Organic Anion Transport Protein SLC21A6 Is Not Sufficient for Bilirubin Transport. J Biol Chem 2003;278:20695-9.
    • (2003) J Biol Chem , vol.278 , pp. 20695-20699
    • Wang, P.1    Kim, R.B.2    Roy Chowdhury, R.3    Wolkoff, A.W.4
  • 116
    • 0027299613 scopus 로고
    • Marked endogenous activation of the CYP1A1 and CYP1A2 genes in the congenitally jaundiced Gunn rat
    • Kapitulnik J, Gonzalez FJ. Marked endogenous activation of the CYP1A1 and CYP1A2 genes in the congenitally jaundiced Gunn rat. Molec Pharmacol 1993;43:722-5.
    • (1993) Molec Pharmacol , vol.43 , pp. 722-725
    • Kapitulnik, J.1    Gonzalez, F.J.2
  • 118
    • 0014594342 scopus 로고
    • Enzymatic oxidation of bilirubin
    • Brodersen R, Bartels P. Enzymatic oxidation of bilirubin. Eur J Biochem 1969;10:468-73.
    • (1969) Eur J Biochem , vol.10 , pp. 468-473
    • Brodersen, R.1    Bartels, P.2
  • 119
    • 0029969862 scopus 로고    scopus 로고
    • Bilirubin-oxidizing activity in rat brain
    • Hansen TWR, Allen JW. Bilirubin-oxidizing activity in rat brain. Biol Neonate 1996;70:289-95.
    • (1996) Biol Neonate , vol.70 , pp. 289-295
    • Hansen, T.W.R.1    Allen, J.W.2
  • 120
    • 0027362731 scopus 로고
    • Uridine diphosphate-glucuronosyltransferase activities in rat brain microsomes
    • Suleman FG, Ghersi-Egea JF, Leininger-Muller B, Minn A. Uridine diphosphate-glucuronosyltransferase activities in rat brain microsomes. Neurosci Lett 1993;161:219-22.
    • (1993) Neurosci Lett , vol.161 , pp. 219-222
    • Suleman, F.G.1    Ghersi-Egea, J.F.2    Leininger-Muller, B.3    Minn, A.4
  • 121
    • 0032410818 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) and their emerging role in cancer
    • LaCasse EC, Baird S, Korneluk RG, MacKenzie AE. The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 1998;17:3247-59.
    • (1998) Oncogene , vol.17 , pp. 3247-3259
    • Lacasse, E.C.1    Baird, S.2    Korneluk, R.G.3    MacKenzie, A.E.4
  • 122
    • 0033082995 scopus 로고    scopus 로고
    • IAP family proteins - Suppressors of apoptosis
    • Deveraux QL, Reed JC. IAP family proteins - suppressors of apoptosis. Genes Dev 1999;13:239-52.
    • (1999) Genes Dev , vol.13 , pp. 239-252
    • Deveraux, Q.L.1    Reed, J.C.2
  • 123
    • 0028858409 scopus 로고
    • Influence of glutathione S-transferase B (ligandin) on the intermembrane transfer of bilirubin - Implications for the intracellular transport of nonsubstrate ligands in hepatocytes
    • Zucker SD, Gössling W, Ransil BJ, Gollan JL. Influence of glutathione S-transferase B (ligandin) on the intermembrane transfer of bilirubin - implications for the intracellular transport of nonsubstrate ligands in hepatocytes. J Clin Invest 1995;98:1927-35.
    • (1995) J Clin Invest , vol.98 , pp. 1927-1935
    • Zucker, S.D.1    Gössling, W.2    Ransil, B.J.3    Gollan, J.L.4
  • 124
    • 0021778327 scopus 로고
    • The isoenzymes of glutathione transferase
    • Mannervik B. The isoenzymes of glutathione transferase. Adv Enzymol Relat Areas Mol Biol 1985;57:357-417.
    • (1985) Adv Enzymol Relat Areas Mol Biol , vol.57 , pp. 357-417
    • Mannervik, B.1
  • 125
    • 0021747526 scopus 로고
    • A comparison of the binding affinities of five forms of rat glutathione-S-transferases for bilirubin, sulfobromophthalein and hematin
    • Sugiyama Y, Sugimoto M, Stolz A, Kaplowitz N. A comparison of the binding affinities of five forms of rat glutathione-S-transferases for bilirubin, sulfobromophthalein and hematin. Biochem Pharmacol 1984;33:3511-3.
    • (1984) Biochem Pharmacol , vol.33 , pp. 3511-3513
    • Sugiyama, Y.1    Sugimoto, M.2    Stolz, A.3    Kaplowitz, N.4
  • 127
    • 0027298361 scopus 로고
    • Effects of hyperbilirubinaemia on glutathione S-transferase isoenzymes in cerebellar cortex of the Gunn rat
    • Johnson JA, Hayward JJ, Kornguth SE, Siegel FL. Effects of hyperbilirubinaemia on glutathione S-transferase isoenzymes in cerebellar cortex of the Gunn rat. Biochem J 1993;291:453-61.
    • (1993) Biochem J , vol.291 , pp. 453-461
    • Johnson, J.A.1    Hayward, J.J.2    Kornguth, S.E.3    Siegel, F.L.4
  • 128
    • 0023845218 scopus 로고
    • Characterization and localization of glutathione-S-transferases in rat brain and binding of hormones, neurotransmitters, and drugs
    • Abramovitz M, Homma H, Ishigaki S, Tansey F, Gammer W, Listowsky I. Characterization and localization of glutathione-S-transferases in rat brain and binding of hormones, neurotransmitters, and drugs. J Neurochem 1988;50:50-7.
    • (1988) J Neurochem , vol.50 , pp. 50-57
    • Abramovitz, M.1    Homma, H.2    Ishigaki, S.3    Tansey, F.4    Gammer, W.5    Listowsky, I.6
  • 129
    • 0037088904 scopus 로고    scopus 로고
    • The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7
    • Maier JK, Lahoua Z, Gendron NH, Fetni R, Johnston A, Davoodi J et al. The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7. J Neurosci 2002;22:2035-43.
    • (2002) J Neurosci , vol.22 , pp. 2035-2043
    • Maier, J.K.1    Lahoua, Z.2    Gendron, N.H.3    Fetni, R.4    Johnston, A.5    Davoodi, J.6
  • 130
    • 13344278692 scopus 로고    scopus 로고
    • Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
    • Liston P, Roy N, Tamai K, Lefebvre C, Baird S, Cherton-Horvat G et al. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature 1996;379:349-53.
    • (1996) Nature , vol.379 , pp. 349-353
    • Liston, P.1    Roy, N.2    Tamai, K.3    Lefebvre, C.4    Baird, S.5    Cherton-Horvat, G.6
  • 131
    • 0032902337 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons
    • Simons M, Beinroth S, Gleichmann M, Liston P, Korneluk RG, MacKenzie AE et al. Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons. J Neurochem 1999;72:292-301.
    • (1999) J Neurochem , vol.72 , pp. 292-301
    • Simons, M.1    Beinroth, S.2    Gleichmann, M.3    Liston, P.4    Korneluk, R.G.5    MacKenzie, A.E.6
  • 132
    • 0030848529 scopus 로고    scopus 로고
    • Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus
    • Xu DG, Crocker SJ, Doucet JP, St Jean M, Tamai K, Hakim AM et al. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nat Med 1997;3:997-1004.
    • (1997) Nat Med , vol.3 , pp. 997-1004
    • Xu, D.G.1    Crocker, S.J.2    Doucet, J.P.3    St. Jean, M.4    Tamai, K.5    Hakim, A.M.6
  • 133
    • 0032127922 scopus 로고    scopus 로고
    • Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein)
    • Yaraghi Z, Korneluk RG, MacKenzie A. Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein). Genomics 1998;51:107-13.
    • (1998) Genomics , vol.51 , pp. 107-113
    • Yaraghi, Z.1    Korneluk, R.G.2    MacKenzie, A.3
  • 135
    • 0031548054 scopus 로고    scopus 로고
    • Distribution of neuronal apoptosis inhibitory protein-like immunoreactivity in the rat central nervous system
    • Xu DG, Korneluk RG, Tamai K, Wigle N, Hakim A, MacKenzie A et al. Distribution of neuronal apoptosis inhibitory protein-like immunoreactivity in the rat central nervous system. J Comp Neurol 1997;382:247-59.
    • (1997) J Comp Neurol , vol.382 , pp. 247-259
    • Xu, D.G.1    Korneluk, R.G.2    Tamai, K.3    Wigle, N.4    Hakim, A.5    MacKenzie, A.6
  • 136
    • 0037171045 scopus 로고    scopus 로고
    • Distinct expression of neuronal apoptosis inhibitory protein (NAIP) during murine development
    • Ingram-Crooks J, Holcik M, Drmanic S, MacKenzie AE. Distinct expression of neuronal apoptosis inhibitory protein (NAIP) during murine development. Neuroreport 2002;13:397-402.
    • (2002) Neuroreport , vol.13 , pp. 397-402
    • Ingram-Crooks, J.1    Holcik, M.2    Drmanic, S.3    MacKenzie, A.E.4
  • 137
    • 0014712426 scopus 로고
    • Studies in kernicterus. III. The saturation of serum proteins with bilirubin during neonatal life and its relationship to brain damage at five years
    • Odell GB, Storey GNB, Rosenberg LA. Studies in kernicterus. III. The saturation of serum proteins with bilirubin during neonatal life and its relationship to brain damage at five years. J Pediatr 1970;76:12-21.
    • (1970) J Pediatr , vol.76 , pp. 12-21
    • Odell, G.B.1    Storey, G.N.B.2    Rosenberg, L.A.3
  • 138
    • 0000560724 scopus 로고
    • Bilirubin-dependent brain damage; Incidence and indication for treatment
    • Odell GB, Schaffer R, Simopoulos AP, editors. Washington D.C.: National Academy of Sciences
    • Johnson LH, Boggs TR Jr. Bilirubin-dependent brain damage; Incidence and indication for treatment. In: Odell GB, Schaffer R, Simopoulos AP, editors. Phototherapy in the Newborn; an Overview. Washington D.C.: National Academy of Sciences; 1974.pp. 122-49.
    • (1974) Phototherapy in the Newborn; An Overview , pp. 122-149
    • Johnson, L.H.1    Boggs Jr., T.R.2
  • 139
    • 0027074097 scopus 로고
    • Determination of serum unbound bilirubin for prediction of kernicterus in low birthweight infants
    • Nakamura H, Yonetani M, Uetani Y, Funato M, Lee Y. Determination of serum unbound bilirubin for prediction of kernicterus in low birthweight infants. Acta Paediatr Jpn 1992;34:642-7.
    • (1992) Acta Paediatr Jpn , vol.34 , pp. 642-647
    • Nakamura, H.1    Yonetani, M.2    Uetani, Y.3    Funato, M.4    Lee, Y.5
  • 140
    • 0028031590 scopus 로고
    • Vigintiphobia, unbound bilirubin and auditory brainstem responses
    • Funato M, Tamai H, Shimada S, Nakamura H. Vigintiphobia, unbound bilirubin and auditory brainstem responses. Pediatrics 1994;93:50-3.
    • (1994) Pediatrics , vol.93 , pp. 50-53
    • Funato, M.1    Tamai, H.2    Shimada, S.3    Nakamura, H.4
  • 141
    • 0034891543 scopus 로고    scopus 로고
    • Auditory brainstem response and unbound bilirubin in jaundiced (jj) Gunn rat pups
    • Ahlfors CE, Shapiro SM. Auditory brainstem response and unbound bilirubin in jaundiced (jj) Gunn rat pups. Biol Neonate 2001;80:158-62.
    • (2001) Biol Neonate , vol.80 , pp. 158-162
    • Ahlfors, C.E.1    Shapiro, S.M.2
  • 143
    • 0027493586 scopus 로고
    • Reversible brainstem auditory evoked potential abnormalities in jaundiced Gunn rats given sulfonamide
    • Shapiro SM. Reversible brainstem auditory evoked potential abnormalities in jaundiced Gunn rats given sulfonamide. Pediatr Res 1993;34:629-33.
    • (1993) Pediatr Res , vol.34 , pp. 629-633
    • Shapiro, S.M.1
  • 144
    • 0020471578 scopus 로고
    • Abnormal auditory brainstem response in a newborn infant with hyperbilirubinaemia: Improvement with exchange transfusion
    • Wennberg RP, Ahlfors CE, Bickers R, McMurtry CA, Shetter JL. Abnormal auditory brainstem response in a newborn infant with hyperbilirubinaemia: improvement with exchange transfusion. J Pediatr 1982;100:624-6.
    • (1982) J Pediatr , vol.100 , pp. 624-626
    • Wennberg, R.P.1    Ahlfors, C.E.2    Bickers, R.3    McMurtry, C.A.4    Shetter, J.L.5
  • 145
    • 0021707067 scopus 로고
    • Changes in auditory brainstem responses in hyperbilirubinemic infants before and after exchange transfusion
    • Nwaesei CG, Van Aerde J, Boyden M, Perlman M. Changes in auditory brainstem responses in hyperbilirubinemic infants before and after exchange transfusion. Pediatrics 1984;74:800-3.
    • (1984) Pediatrics , vol.74 , pp. 800-803
    • Nwaesei, C.G.1    Van Aerde, J.2    Boyden, M.3    Perlman, M.4
  • 146
    • 0035687332 scopus 로고    scopus 로고
    • Criteria for treatment of neonatal jaundice
    • Bratlid D. Criteria for treatment of neonatal jaundice. J Perinatol 2001;21 (Suppl. 1):S88-S92.
    • (2001) J Perinatol , vol.21 , Issue.1 SUPPL.
    • Bratlid, D.1
  • 147
    • 0035895894 scopus 로고    scopus 로고
    • Aromatic hydrocarbon receptor (AhR) AhR nuclear translocator- And p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells
    • Mathieu MC, Lapierre I, Brault K, Raymond M. Aromatic hydrocarbon receptor (AhR) AhR nuclear translocator-and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a) pyrene in hepatoma cells. J Biol Chem 2001;276:4819-27.
    • (2001) J Biol Chem , vol.276 , pp. 4819-4827
    • Mathieu, M.C.1    Lapierre, I.2    Brault, K.3    Raymond, M.4
  • 148
    • 0034599817 scopus 로고    scopus 로고
    • Monitoring of cytochrome P-450 1A activity by determination of the urinary pattern of caffeine metabolites in Wistar and hyperbilirubinemic Gunn rats
    • Jorritsma U, Schrader E, Klaunick G, Kapitulnik J, Hirsch-Ernst KI, Kahl GF et al. Monitoring of cytochrome P-450 1A activity by determination of the urinary pattern of caffeine metabolites in Wistar and hyperbilirubinemic Gunn rats. Toxicology 2000;144:229-36.
    • (2000) Toxicology , vol.144 , pp. 229-236
    • Jorritsma, U.1    Schrader, E.2    Klaunick, G.3    Kapitulnik, J.4    Hirsch-Ernst, K.I.5    Kahl, G.F.6


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