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Volumn 13, Issue 5, 2003, Pages 819-822

Heterologous expression of hybrid type II polyketide synthase system in Streptomyces species

Author keywords

Actinorhodin; Hybrid polyketide; Oxytetracycline; Streptomyces

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; ACETYL COENZYME A; ACTINORHODINE; ANTHRAQUINONE; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; FLUORESCENT DYE; HYBRID PROTEIN; MALONYL COENZYME A; POLYKETIDE; POLYKETIDE SYNTHASE;

EID: 0242551358     PISSN: 10177825     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (23)
  • 1
    • 0024996111 scopus 로고
    • Biosynthesis of anthraquinones by interspecies cloning of actinorhodin biosynthesis genes in streptomycetes: Clarification of actinorhodin gene functions
    • Bartel, P. L., C.-B. Zhu, J. S. Lampel, D. C. Dosch, N. C. Conners, W. R. Strohl, J. M. Beale, and H. G. Floss. 1990. Biosynthesis of anthraquinones by interspecies cloning of actinorhodin biosynthesis genes in streptomycetes: Clarification of actinorhodin gene functions. J. Bacteriol. 172: 4816-4826.
    • (1990) J. Bacteriol. , vol.172 , pp. 4816-4826
    • Bartel, P.L.1    Zhu, C.-B.2    Lampel, J.S.3    Dosch, D.C.4    Conners, N.C.5    Strohl, W.R.6    Beale, J.M.7    Floss, H.G.8
  • 2
    • 0014202424 scopus 로고
    • Biosynthesis of polyketides and related compounds
    • Birch, A. J. 1967. Biosynthesis of polyketides and related compounds. Science 156: 202-206.
    • (1967) Science , vol.156 , pp. 202-206
    • Birch, A.J.1
  • 3
    • 0036094829 scopus 로고    scopus 로고
    • Identification of Streptomyces sp. producing new polyene antibiotics and in vivo antimicrobial activity of tetrin C against phytopathogenic fungi
    • Choi, W.-C., S.-Y. Hwang, T.-K. Park, and S.-K. Kim. 2002, Identification of Streptomyces sp. producing new polyene antibiotics and in vivo antimicrobial activity of tetrin C against phytopathogenic fungi. J. Microbiol. Biotechnol. 12: 204-208.
    • (2002) J. Microbiol. Biotechnol. , vol.12 , pp. 204-208
    • Choi, W.-C.1    Hwang, S.-Y.2    Park, T.-K.3    Kim, S.-K.4
  • 4
    • 34848847286 scopus 로고
    • Derivatives of the multiple keten group
    • Collie, J. N. 1907. Derivatives of the multiple keten group. J. Chem. Soc. 91: 1806-1813.
    • (1907) J. Chem. Soc. , vol.91 , pp. 1806-1813
    • Collie, J.N.1
  • 5
    • 0025081416 scopus 로고
    • An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea
    • Cortes, J., S. F. Haydock, G. A. Roberts, D. J. Bevitt, and P. F. Leadlay. 1990. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea. Nature 346: 176-178.
    • (1990) Nature , vol.346 , pp. 176-178
    • Cortes, J.1    Haydock, S.F.2    Roberts, G.A.3    Bevitt, D.J.4    Leadlay, P.F.5
  • 6
    • 0026657813 scopus 로고
    • Nucleotide sequences and deduced functions of a set of cotranslated genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin
    • Fernandez-Moreno, M. A., E. Martinez, L. Boto, D. A. Hopwood, and F. Malpartida. 1992. Nucleotide sequences and deduced functions of a set of cotranslated genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin. J. Biol. Chem. 267: 19278-19290.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19278-19290
    • Fernandez-Moreno, M.A.1    Martinez, E.2    Boto, L.3    Hopwood, D.A.4    Malpartida, F.5
  • 7
    • 0023684064 scopus 로고
    • A general method of in vitro preparation and specific mutagenesis of DNA fragments: Study of protein and DNA interactions
    • Higuchi, R. B., B. Krummel, and R. K. Saiki. 1988. A general method of in vitro preparation and specific mutagenesis of DNA fragments: Study of protein and DNA interactions. Nucleic Acids Res. 16: 7351-7367.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 7351-7367
    • Higuchi, R.B.1    Krummel, B.2    Saiki, R.K.3
  • 8
    • 0035167889 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the doxA cytochrome P-450 hydroxylase gene in Streptomyces peucetius subsp. caesius ATCC 27952
    • Hong, Y.-S., H. S. Kim, J.-H. Lee, K.-W. Kim, and J. J. Lee. 2001. Molecular cloning and characterization of the doxA cytochrome P-450 hydroxylase gene in Streptomyces peucetius subsp. caesius ATCC 27952. J. Microbiol. Biotechnol. 11: 895-898.
    • (2001) J. Microbiol. Biotechnol. , vol.11 , pp. 895-898
    • Hong, Y.-S.1    Kim, H.S.2    Lee, J.-H.3    Kim, K.-W.4    Lee, J.J.5
  • 9
    • 0025606149 scopus 로고
    • Molecular genetics of polyketides and its comparison to fatty acid biosynthesis
    • Hopwood, D. A. and D. H. Sherman. 1990. Molecular genetics of polyketides and its comparison to fatty acid biosynthesis. Annu. Rev. Genet. 24: 37-66.
    • (1990) Annu. Rev. Genet. , vol.24 , pp. 37-66
    • Hopwood, D.A.1    Sherman, D.H.2
  • 10
    • 0028811381 scopus 로고
    • Polyketide synthase gene manipulation: A structure-function approach in engineering novel antibiotics
    • Hutchinson, C. R. and I. Fujii. 1995. Polyketide synthase gene manipulation: A structure-function approach in engineering novel antibiotics. Annu. Rev. Microbiol. 49: 201-238.
    • (1995) Annu. Rev. Microbiol. , vol.49 , pp. 201-238
    • Hutchinson, C.R.1    Fujii, I.2
  • 11
    • 0027382486 scopus 로고
    • Polyketide synthesis: Prospects for hybrid antibiotics
    • Katz, L. and S. Donadio. 1993. Polyketide synthesis: Prospects for hybrid antibiotics. Annu. Rev. Microbiol. 47: 875-912.
    • (1993) Annu. Rev. Microbiol. , vol.47 , pp. 875-912
    • Katz, L.1    Donadio, S.2
  • 12
    • 0026539625 scopus 로고
    • Targeted gene replacements in a Streptomyces polyketide synthase gene cluster: Role for the acyl carrier protein
    • Khosla, C., S. Ebert-Khosla, and D. A. Hopwood. 1992. Targeted gene replacements in a Streptomyces polyketide synthase gene cluster: Role for the acyl carrier protein. Mol. Microbiol. 6: 3237-3249.
    • (1992) Mol. Microbiol. , vol.6 , pp. 3237-3249
    • Khosla, C.1    Ebert-Khosla, S.2    Hopwood, D.A.3
  • 13
    • 0027315216 scopus 로고
    • Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins
    • Khosla, C., R. McDaniel, S. Ebert-Khosla, R. Torres, D. H. Sherman, M. J. Bibb, and D. A. Hopwood. 1993. Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins. J. Bacteriol. 175: 2197-2204.
    • (1993) J. Bacteriol. , vol.175 , pp. 2197-2204
    • Khosla, C.1    McDaniel, R.2    Ebert-Khosla, S.3    Torres, R.4    Sherman, D.H.5    Bibb, M.J.6    Hopwood, D.A.7
  • 15
    • 0028204797 scopus 로고
    • Analysis of type II polyketide β-ketoacyl synthase specificity in Streptomyces coelicolor A3(2) by trans complementation of actinorhodin synthase mutants
    • Kim, E.-S., D. A. Hopwood, and D. H. Sherman. 1994. Analysis of type II polyketide β-ketoacyl synthase specificity in Streptomyces coelicolor A3(2) by trans complementation of actinorhodin synthase mutants. J. Bacteriol. 176: 1801-1804.
    • (1994) J. Bacteriol. , vol.176 , pp. 1801-1804
    • Kim, E.-S.1    Hopwood, D.A.2    Sherman, D.H.3
  • 16
    • 0028935276 scopus 로고
    • Heterologous expression of an engineered biosynthetic pathway: Functional dissection of type II polyketide synthase components in Streptomyces species
    • Kim, E.-S., K. D. Cramer, A. L. Shreve, and D. H. Sherman. 1995. Heterologous expression of an engineered biosynthetic pathway: Functional dissection of type II polyketide synthase components in Streptomyces species. J. Bacteriol. 177: 1202-1207.
    • (1995) J. Bacteriol. , vol.177 , pp. 1202-1207
    • Kim, E.-S.1    Cramer, K.D.2    Shreve, A.L.3    Sherman, D.H.4
  • 17
    • 0028324248 scopus 로고
    • Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    • Kim, E.-S., M. J. Bibb, M. J. Butler, D. A. Hopwood, and D. H. Sherman. 1994. Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus. Gene 141: 141-142.
    • (1994) Gene , vol.141 , pp. 141-142
    • Kim, E.-S.1    Bibb, M.J.2    Butler, M.J.3    Hopwood, D.A.4    Sherman, D.H.5
  • 18
    • 0021238139 scopus 로고
    • Molecular cloning of the whole biosynthetic pathway of a Streptomyces antibiotic and its expression in a heterologous host
    • Malpartida, F. and D. A. Hopwood. 1984. Molecular cloning of the whole biosynthetic pathway of a Streptomyces antibiotic and its expression in a heterologous host. Nature 309: 462-464.
    • (1984) Nature , vol.309 , pp. 462-464
    • Malpartida, F.1    Hopwood, D.A.2
  • 19
    • 0023001541 scopus 로고
    • Physical and genetic characterization of the gene cluster for the antibiotic actinorhodin in Streptomyces coelicolor A3(2)
    • Malpartida, F. and D. A. Hopwood. 1986. Physical and genetic characterization of the gene cluster for the antibiotic actinorhodin in Streptomyces coelicolor A3(2). Mol. Gen. Genet. 205: 66-73.
    • (1986) Mol. Gen. Genet. , vol.205 , pp. 66-73
    • Malpartida, F.1    Hopwood, D.A.2
  • 20
    • 0027746346 scopus 로고
    • Engineered biosynthesis of novel polyketides: Manipulation and analysis of an aromatic polyketide synthase with unproven catalytic specificities
    • McDaniel, R., S. Ebert-Khosla, D. A. Hopwood, and C. Khosla. 1993. Engineered biosynthesis of novel polyketides: Manipulation and analysis of an aromatic polyketide synthase with unproven catalytic specificities. J. Am. Chem. Soc. 115: 11671-11675.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 11671-11675
    • McDaniel, R.1    Ebert-Khosla, S.2    Hopwood, D.A.3    Khosla, C.4
  • 22
    • 0027766247 scopus 로고
    • Biosynthesis of fatty acid and polyketide metabolites
    • O'Hagan, D. 1993. Biosynthesis of fatty acid and polyketide metabolites. Nat. Prod. Rep. 10: 593-624.
    • (1993) Nat. Prod. Rep. , vol.10 , pp. 593-624
    • O'Hagan, D.1
  • 23
    • 0026738080 scopus 로고
    • Functional replacement of genes for individual polyketide synthase components in Streptomyces coelicolor A3(2) by heterologous genes from a different polyketide pathway
    • Sherman, D. H., E.-S. Kim, M. J. Bibb, and D. A. Hopwood. 1992. Functional replacement of genes for individual polyketide synthase components in Streptomyces coelicolor A3(2) by heterologous genes from a different polyketide pathway. J. Bacteriol. 174: 6184-6190.
    • (1992) J. Bacteriol. , vol.174 , pp. 6184-6190
    • Sherman, D.H.1    Kim, E.-S.2    Bibb, M.J.3    Hopwood, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.