The effect of three different doses of intrathecal MgSO4 on spinal opioid analgesia

Egyptian Journal of Anaesthesia

Volumn 19, Issue 4, 2003, Pages 405-409

  Marzouk, Sahar ^a   Abd El Hady, Nagla ^a   Lotfy, Moona ^a   Darwish, Hisham M ^b  

^a CAIRO UNIVERSITY   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Fentanyl; Intrathecal opioids; Magnesium sulphate; Postoperative analgesia

Indexed keywords

ADRENALIN; CLONIDINE; FENTANYL; ISOFLURANE; MAGNESIUM SULFATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEOSTIGMINE; NITROUS OXIDE; OPIATE; PETHIDINE;

ADULT; ANESTHESIA INDUCTION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; HUMAN; INTERMETHOD COMPARISON; KNEE ARTHROSCOPY; MAJOR CLINICAL STUDY; MALE; PAIN ASSESSMENT; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SEDATION; SPINAL ANESTHESIA; VISUAL ANALOG SCALE;

EID: 0242543833     PISSN: 11101849     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Begum R, Begum A, Aullough CH, Johanson RB: Reducing maternal mortality from eclampsia using magnesium sulphate. Eur J Obstet Gynaecol Reprod Biol 2000;92:223-224.
2. Tramer MR, Shneider J, René-Andreas M, Rifai K: Role of magnesium sulfate in postoperative analgesia. Anesthesiology 1996;84:340-347.
3. Koinig H, Wallner T, Marhofer P, et al: Magnesium sulfate reduces intra- and postoperative analgesic requirements. Anesth Analg 1998;87:206-210.
4. Lodge D, Johnson KM: Non-competitive excitatory amino acid receptor antagonists. Trends Pharmacol Sci 1990;11:81-86.
5. Iseri LT, French JH: Magnesium nature's physiologic calcium blocker (editorial). Am Heart J 1984;108:188-194.
6. 2+ channel blockers. Eur J Pharmacol 1992;217:137-141.
7. Wong CH, Dey P, Yarmush J et al: Nifedipine-induced analgesia after epidural injection in rats. Anesth Analg 1994;79:303-306.
8. Thurnau GR, Kemp DB, Jarvis A: Cerebrospinal fluid levels of magnesium in patients with pre-eclampsia after treatment with intravenous magnesium sulfate: A preliminary report. Am J Obstet Gynecol 1987;157:1435-1438.
9. Jeffrey S, McCarthy RJ, von Roenn N, et al: Magnesium sulfate potentiates morphine antinociception at the spinal level. Anesth Analg 2000;90:913-917.
10. Xiao W, Bennett G: Magnesium suppresses neuropathic pain response in rats via a spinal site of action. Brain Res 1994;666:168-172.
11. Chanimov M, Cohen ML, Grinspun Y, et al: Neurotoxicity after spinal anaesthesia induced by serial intrathecal injections of magnesium sulphate: An experimental study in a rat model. Anaesthesia 1997;52:223-228.
12. Simpson JI, Eide TR, Schiff GS, et al: Intrathecal magnesium sulfate protects the spinal cord from ischemic injury during thoracic aortic cross clamping. Anesthesiology 1994;81:1493-1499.
13. Askumar B, Robert J, McCarthy, et al: Intrathecal magnesium prolongs fentanyl analgesia: A prospective randomized controlled trial. Anesth Analg 2002;95:661-666.
14. Behar M, Olshwang D, Magora F, Davidson JT: Epidural morphine in the treatment of pain. Lancet 1979;1:527-529.
15. Wang JK, Nauss LA, Thomas JE: Pain relief by intrathecally applied morphine in man. Anesthesiology 1979;50:149-151.
16. Gustafsson LL, Schildt B, Jacobsenk: Adverse of extraduration intrathecal opiates: Report of a nationwide survey in Sweden. Br J Anaesth 1982;54: 479-486.
17. Asokumar B, Newman ML, McCarthy RJ, et al: Intrathecal bupivacaine reduces pruritus and prolongs duration of fentanyl analgesia during labor. A prospective randomized controlled trial. Anesth Analg 1998;87:1309-1315.
18. Campbell DC, Banner R, Crone LA, et al: Addition of epinephrine to intrathecal bupivacaine and sufentanil for ambulatory labor analgesia. Anesthesiology 1997;86:525-531.
19. D'Angelo R, Evans E, Laura D, et al: Spinal clonidine prolongs labor analgesia from spinal sufentanil and bupivacaine. Anesth Analg 1999;88: 573-576.
20. Owen MD, Ozsara CO, Sahin S, et al: Low dose clonidine and neostigmine prolong the duration of intrathecal bupivacaine-fentanyl for labor analgesia. Anesthesiology 2000;92:361-366.
21. Woolf CJ, Thompson SW: The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation. Implications for the treatment of post-injury pain and hypersensitivity states. Pain 1991;44:293-299.
22. Liu HT, Hillman MW, Liu WH, et al: Modulation of NMDA receptor function by ketamine and magnesium. Part 2. Anesth Analg 2001;92:1173-1181.
23. Ascher P, Nowak L: Electrophysiological studies of NMDA receptors. Trend Neurosci 1987;10:284-288.
24. Ko SH, Lim HR, Kim DC, et al: Magnesium sulfate doesn't reduce postoperative analgesic requirements. Anesthesiology 2001;95:640-646.
25. Haubold HA, Meltzer SJ: Spinal anesthesia by magnesium sulfate. JAMA 1906;46:647-650.
26. Lejuste MJ: Inadvertent intrathecal administration of magnesium sulfate. South Africa Med J 1985;68: 367-368.