Possible Role of L-Carnosine in the Regulation of Blood Glucose through Controlling Autonomic Nerves

Experimental Biology and Medicine

Volumn 228, Issue 10, 2003, Pages 1138-1145

  Nagai, Katsuya ^a   Niijima, Akira ^b   Yamano, Toshihiko ^a   Otani, Hiroto ^a   Okumra, Nobuaki ^a   Tsuruoka, Nobuo ^c   Nakai, Masaaki ^b   Kiso, Yoshinobu ^c  

^a OSAKA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c SUNTORY LTD   (Japan)

Author keywords

Diabetes; Exercise; Food intake; Histamine; Histidine

Indexed keywords

ALPHA FLUOROMETHYLHISTIDINE; CARNOSINE; DEOXYGLUCOSE; DIPHENHYDRAMINE; HISTAMINE; HISTAMINE H3 RECEPTOR; HISTIDINE; THIOPERAMIDE;

ANIMAL EXPERIMENT; AUTONOMIC NERVOUS SYSTEM; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; EXERCISE; FOOD INTAKE; GASTROCNEMIUS MUSCLE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; MALE; NEUROMODULATION; NONHUMAN; RAT;

ANIMALIA; MAMMALIA;

EID: 0242525249     PISSN: 15353702     EISSN: None     Source Type: Journal    
DOI: 10.1177/153537020322801007     Document Type: Conference Paper

References (19)

1. Boldyreve AA, Severin SE. The histidine-containing dipeptides, carnosine and anserine: Distribution, properties and biological significance. Adv Enzyme Regul 39:175-194, 1990.
2. Buse MG, Weigand DA, Peeler D, Hedden MP. The effect of diabetes and the redox potential on amino acid content and release by isolated rat hemidiaphragms. Metabolism 29:605-616, 1980.
3. Yamano T, Niijima A, Iimori S, Tsuruoka N, Kiso Y, Nagai K. Effects of L-camosine on the hyperglycemia caused by intracranial injection of 2-deoxy-D-glucose in rats. Neurosci Lett 31:78-82, 2001.
4. Chun S, Niijima A, Nagai N, Nagai K. Effect of bilateral lesions of the suprachiasmatic nucleus of the hyperglycemia caused by 2-deoxy-D-glucose and vasoactive intestinal peptide in rats. Brain Res 809:165-174, 1998.
5. Fujiwara M, Ishida Y, Nimura N, Toyama A, Kinoshita T. Postcolumn fluorometric detection system for liquid chromatographic analysis of amino and imino acids using o-phthalaldehyde/N-acetyl-L-cystein reagent. Anal Biochem 166:72-78, 1987.
6. Bando K, Shimotuji T, Toyoshima H, Hayashi C, Miyai K. Fluorometric assay of human serum camosinase activity in normal children, adults and patients with myopathy. Ann Clin Biochem 21:510-514, 1984.
7. Horinishi H, Grillo M, Margolis FL. Purification and characterization of camosine synthetase from mouse olfactory bulbs. J Neurochem 31:909-919, 1978.
8. Rosario M, Wood G, Johnson P. Purification of camosine synthetase from avian muscle by affinity chromatography and determination of its subunit structure. Biochim Biophys Acta 662:138-144, 1981.
9. Smith GP, Stromayer J, Strokes PE. Threshold doses of 2-deoxy-D-glucose for hyperglycemia and feeding in rats and monkeys. Am J Physiol 222:77-81, 1972.
10. Nagai K, Nagai N, Shimizu K, Chun S, Nakagawa H, Niijima A. SCN output drives the autonomic nervous system: with special reference to the autonomic function related to the regulation of glucose metabolism. In: Buijs RM, Kalsbeek A, Romijn HJ, Pennartz C.Mirmiran M, Eds. Hypothalamic Integration of Circadian Rhythms. Progr Brain Res. Amsterdam: Elsevier, Vol 111: pp253-272, 1996.
11. Yamamoto H, Nagai K, Nakagawa H. Time-dependent involvement of autonomic nervous system in hyperglycemia due to 2-deoxy-D-glucose. Am J Physiol 255:E928-E933, 1988.
12. Nagai K, Niijima A, Nagai N, Hibino H, Chun S, Shimizu K, Nakagawa H. Bilateral lesions of the hypothalamic suprachiasmatic nucleus eliminated sympathetic response to intracranial injection of 2-deoxy-D-glucose and VIP rescued this response. Brain Res Bull 39:293-297, 1996.
13. Chun S, Niijima A, Nagai N, Nagai K. Effect of bilateral lesions of the suprachiasmatic nucleus on hyperglucemia caused by 2-deoxy-D-glucose and vasoactive interatinal peptide in rats. Brain Res 809:165-174, 1998.
14. Niijima A, Okui T, Matsumura Y, Yamano T, Tsumoka N, Kiso Y, Nagai K. Effects of L-camosine on renal sympathetic nerve activity and DOCA-salt hypertension in rats. Auton Neurosci: Basic Clinical 97:99-102, 2002.
15. Woods SC, Porte D Jr. Neural control of endocrine pancreas. Physiol Rev 54:596-619, 1974.
16. Tsuda K, Yoshimatsu H, Niijima A, Chiba S, Okeda T, Sakata T. Hypothalamic histamine neurons activate lipolysis in rat adipose tissue. Exp Biol Med 227:208-213, 2002.
17. Arrang JM, Devaux B, Chodkiewicz JP, Schwartz JC. H3-receptors control histamine release in human brain. J Neurochem 51:105-108, 1988.
18. Yoshimatsu H, Chiba S, Tajima D, Akehi Y, Sakata T. Histidine suppresses food intake through its conversion into neuronal histamine. Exp Biol Med. 227:63-68, 2002.
19. Yoshimatsu H, Itateyama E, Kondou S, Tajima D, Himeno K, Hidaka S, Kurokawa M, Sakata T. Hypothalamic neuronal histamine as a target of leptin in feeding behavior. Diabetes 48:2286-2291, 1999.