An Expeditious Synthesis of 1-(4-Chlorophenyl)-3,3-dimethyl-2-butanone by a Ligand-Free Palladium-Catalyzed α-Arylation of Pinacolone: Scale-Up and Effect of Base Concentration

Advanced Synthesis and Catalysis

Volumn 345, Issue 4, 2003, Pages 533-536

  Prashad, Mahavir ^a   Liu, Yugang ^a   Repič, Oljan ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

arylation; Ketones; Ligand free homogeneous catalysis; Palladium; Pinacolone

Indexed keywords

1 (4 CHLOROPHENYL) 3,3 DIMETHYL 2 BUTANONE; 2 BUTANONE; PALLADIUM COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

EID: 0242522408     PISSN: 16154150     EISSN: None     Source Type: Journal    
DOI: 10.1002/adsc.200390062     Document Type: Article

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