Practical Aspects of Randomization and Blinding in Randomized Clinical Trials

Arthroscopy - Journal of Arthroscopic and Related Surgery

Volumn 19, Issue 9, 2003, Pages 1000-1006

  Bridgman, Stephen ^a   Dainty, Katie ^b   Kirkley, Alexandra ^b   Maffulli, Nicola ^a  

^a KEELE UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Bias; Blinding; Randomization; Research methodology; Treatment allocation

Indexed keywords

ARTICLE; CLINICAL RESEARCH; CONTROLLED STUDY; EXPERIMENTAL DESIGN; HUMAN; METHODOLOGY; MINIMIZATION TECHNIQUE; PSEUDORANDOMIZATION; RANDOMIZATION; RESOURCE ALLOCATION; STATISTICAL ANALYSIS; STRATIFICATION; VALIDATION PROCESS;

EID: 0242510091     PISSN: 07498063     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arthro.2003.09.023     Document Type: Review

References (11)

1. Altman DG, Schulz KF, Moher D, Egger M, Davidoff F, Elbourne D, et al. for the CONSORT Group. The revised CONSORT statement for reporting randomized trials: Explanation and elaboration. Ann Intern Med 2001;134:663-694.
2. Pocock SJ. Clinical trials: A practical approach. Chichester: Wiley, 1984.
3. Sackett DL, Haynes RB, Tugwell P. Clinical Epidemiology: A Basic Science for Clinical Medicine. Boston: Little, Brown, 1985.
4. Holme I. Kvalitetskriterier i intervensjonsstudier. Norsk Idrettsmedisin 2002;2:20-24.
5. Stat Med 1999;18:1905-1942.
6. Grady C. Ethical principles in clinical research. In: Gallin JL, ed. Principles and practice of clinical research. London: Academic, 2002;15-26.
7. Manolio TA. Design and conduct of observational studies and clinical trials. In: Gallin JL, ed. Principles and practice of clinical research. London: Academic, 2002;187-206.
8. Harth SC, Thong Y. Aftercare for participants in clinical research. Ethical consideration in an asthma drug trial. J Med Ethics 1995;21:225-228.
9. Califf RM. Large clinical trials: Clinical research institutes. In: Gallin JL, ed. Principles and practice of clinical research. London: Academic, 2002;234.
10. Karlkowski TR. Ascorbic acid for the common cold: A prophylactic and therapeutic trial. JAMA 1975;231:1038-1042.
11. Henkin RI. A double blind study of the affects of zinc-sulfate on taste and smell dysfunction. Am J Med Sci 1976;272:285-289.