Half-of-the-sites reactivity of outer-membrane phospholipase A against an active-site-directed inhibitor

European Journal of Biochemistry

Volumn 260, Issue 3, 1999, Pages 794-800

  Ubarretxena Belandia, Iban ^b   Cox, Ruud C ^b   Dijkman, Ruud ^b   Egmond, Maarten R ^b   Verheij, Hubertus M ^b   Dekker, Niek ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NONE

Author keywords

Half of the sites reactivity; Inhibition; Outer membrane; Phospholipase; Phosphonate

Indexed keywords

1,4 NITROPHENYLOCTYLPHOSPHONATE 2 TRIDECYLCARBAMOYL 3 ETHANESULFONYLAMINO 3 DEOXYGLYCEROL; ENZYME INHIBITOR; PHOSPHOLIPASE A; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; MICELLE; OUTER MEMBRANE; PH; PRIORITY JOURNAL; SOLUBILITY; STOICHIOMETRY; STRUCTURE ANALYSIS; SYNTHESIS;

BINDING SITES; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; PHOSPHOLIPASES A; PHOSPHOLIPIDS; STAPHYLOCOCCUS; SUBSTRATE SPECIFICITY;

EID: 0242508142     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00221.x     Document Type: Article

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