Fatal central nervous system lesions emerging during anti-CD20 monoclonal antibody therapy (rituximab) for a post transplantation Epstein Barr virus-linked lymphoma [2]

Medical and Pediatric Oncology

Volumn 40, Issue 6, 2003, Pages 408-409

  Sirvent von Bueltzingsloewen, Anne ^a   Sirvent, Nicolas ^a   Morand, Patrice ^b   Cassuto, Jill Patrice ^a  

^a CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

^b CHU La Tronche and University   (France)

Author keywords

Anti CD20 antibody; Chronic myelomonocytic leukemia; CNS toxicity; EBV linked lymphoma; Rituximab; Transplantation

Indexed keywords

CYCLOSPORIN; RITUXIMAB; STEROID; THYMOCYTE ANTIBODY;

AUTOPSY; B CELL LYMPHOMA; CANCER RECURRENCE; CANCER REGRESSION; CASE REPORT; CAUSE OF DEATH; CELL TRANSPLANTATION; CEREBROSPINAL FLUID ANALYSIS; CHRONIC MYELOID LEUKEMIA; CLINICAL FEATURE; DRUG INFUSION; EPSTEIN BARR VIRUS; FOLLOW UP; GRAFT VERSUS HOST REACTION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; LETTER; MALE; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT FAILURE; TREATMENT OUTCOME; VIRUS LOAD;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; CHILD, PRESCHOOL; CORD BLOOD STEM CELL TRANSPLANTATION; DNA, NEOPLASM; DNA, VIRAL; ENCEPHALITIS; EPSTEIN-BARR VIRUS INFECTIONS; FATAL OUTCOME; HERPESVIRUS 4, HUMAN; HUMANS; IN SITU HYBRIDIZATION; LEUKEMIA, MYELOMONOCYTIC, CHRONIC; LYMPHOMA, B-CELL; LYMPHOMA, LARGE-CELL; MALE; POLYMERASE CHAIN REACTION;

EID: 0242500773     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/mpo.10209     Document Type: Letter

References (6)

1. Faye A, Quartier P, Reguerre Y, et al. Chimaeric anti-CD20 monoclonal antibody (rituximab) in post-transplant B-lymphoproliferative disorder following stem cell transplantation in children. Br J Haematol 2001;115:112-118.
2. Milpied N, Vasseur B, Parquet N, et al. Humanized anti-CD20 monoclonal antibody (Rituximab) in post transplant B-lymphoproliferative disorder: A retrospective analysis on 32 patients. Ann Oncol 2000;11:S113-S116.
3. Brengel-Pesce K, Morand P, Schmuck A. et al. Routine use of Real-Time quantitative PCR for laboratory diagnosis of Epstein-Barr virus infections. J Med Virol 2002;66:360-369.
4. Cingolani A, Gastaldi R, Fassone L, et al. Epstein-Barr virus infection is predictive of CNS involvement in systemic AIDS-related non-Hodgkin's lymphomas. J Clin Oncol 2000;18:3325-3330.
5. Ruhstaller TW, Amsler U, Cerny T. Rituximab: active treatment of central nervous system involvement by non-Hodgkin's lymphoma? Ann Oncol 2000;11:374-375.
6. Hänel M, Fiedler F, Thorns C. Anti-CD20 monoclonal antibody (Rituximab) and Cidofovir as successful treatment of an EBV-associated lymphoma with CNS involvement. Onkologie 2001;24:491-494.