The Enzymatic Activity of CEM15/Apobec-3G Is Essential for the Regulation of the Infectivity of HIV-1 Virion but Not a Sole Determinant of Its Antiviral Activity

Journal of Biological Chemistry

Volumn 278, Issue 45, 2003, Pages 44412-44416

  Shindo, Keisuke ^b   Takaori Kondo, Akifumi ^a   Kobayashi, Masayuki ^b   Abudu, Aierken ^b   Fukunaga, Keiko ^b   Uchiyama, Takashi ^b  

^a KYOTO UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DNA; ENZYMES; MUTAGENESIS; MUTAGENS; VIRUSES;

HUMAN IMMUNODEFICIENCY VIRUS (HIV);

IMMUNOLOGY;

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; CYTIDINE DEAMINASE; MUTANT PROTEIN; PROTEIN; PROTEIN CEM15; UNCLASSIFIED DRUG; VIF PROTEIN; VIRUS DNA;

AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DELETION MUTANT; DIMERIZATION; DNA SEQUENCE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; REGULATORY MECHANISM; RNA EDITING; SITE DIRECTED MUTAGENESIS; VIRION; VIRUS INFECTIVITY; WILD TYPE;

ANTIVIRAL AGENTS; BASE SEQUENCE; BINDING SITES; CELL LINE; CYTIDINE DEAMINASE; DIMERIZATION; DNA; GENE DELETION; GENE EXPRESSION; HIV-1; HUMANS; IMMUNOSORBENT TECHNIQUES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEOSIDE DEAMINASES; POINT MUTATION; PROTEINS; REPRESSOR PROTEINS; RNA EDITING; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

DNA VIRUSES; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0242497878     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300376200     Document Type: Article

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