Simultaneous measurement of angular and spectral properties of light scattering for characterization of tissue microarchitecture and its alteration in early precancer

IEEE Journal on Selected Topics in Quantum Electronics

Volumn 9, Issue 2, 2003, Pages 243-256

  Kim, Young L ^a   Liu, Yang ^a   Wali, Ramesh K ^b   Roy, Hemant K ^b   Goldberg, Michael J ^b   Kromin, Alexey K ^a   Chen, Kun ^a   Backman, Vadim ^a  

^a Northwestern University   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cancer diagnosis; Fractal dimension; Light scattering; Mie theory; Polarization gating

Indexed keywords

BLOOD; CARCINOGENS; CELLS; DENSITY (SPECIFIC GRAVITY); DIAGNOSIS; LIGHT POLARIZATION; LIGHT SCATTERING; MATHEMATICAL MODELS; TISSUE; TUMORS;

CARCINOGENESIS; EPITHELIUM; FRACTAL DIMENSION; MIE THEORY; PRECANCER; RED BLOOD CELLS; TISSUE MICROARCHITECTURE;

MEDICAL IMAGING;

EID: 0242493217     PISSN: 1077260X     EISSN: None     Source Type: Journal    
DOI: 10.1109/JSTQE.2003.814183     Document Type: Article

References (40)

1. A. G. Yodh and B. Chance, "Spectroscopy and imaging with diffusing light," Phys. Today, vol. 48, pp. 34-40, 1995.
2. J. R. Mourant, I. J. Bigio, J. Boyer, R. L. Conn, T. Johnson, and T. Shimada, "Spectroscopic diagnosis of bladder cancer with elastic light scattering," Laser Surg. Med., vol. 17, pp. 350-357, 1995.
3. S. K. Gayen and R. R. Alfano, "Sensing lesions in tissues with light," Opt. Exp., vol. 4, pp. 475-480, 1999.
4. G. Zonios, L. T. Perelman, V. Backman, R. Manoharan, M. Fitzmaurice, J. Van Dam, and M. S. Feld, "Diffuse reflectance spectroscopy of human adenomatous colon polyps in vivo," Appl. Opt., vol. 38, pp. 6628-6637, 1999.
5. K. Sokolov, R. A. Drezek, K. Gossage, and R. R. Richards-Kortum, "Reflectance spectroscopy with polarized light: Is it sensitive to cellular and nuclear morphology," Opt. Exp., vol. 5, pp. 302-317, 1999.
6. I. J. Bigio, S. G. Bown, G. Briggs, C. Kelley, S. Lakhani, D. Pickard, P. M. Ripley, I. G. Rose, and C. Saunders, "Diagnosis of breast cancer using elastic-scattering spectroscopy: Preliminary clinical results," J. Biomed. Opt., vol. 5, pp. 221-228, 2000.
7. A. E. Cerussi, D. Jakubowski, N. Shah, F. Bevilacqua, R. Lanning, A. J. Berger, D. Hsiang, J. Butler, R. F. Holcombe, and B. J. Tromberg, "Spectroscopy enhances the information content of optical mammography," J. Biomed. Opt., vol. 7, pp. 60-71, 2002.
8. Y. L. Yang, E. J. Celmer, J. A. Koutcher, and R. R. Alfano, "DNA and protein changes caused by disease in human breast tissues probed by the Kubelka-Munk spectral function," Photochem. Photobiol., vol. 75, pp. 627-632, 2002.
9. M. E. Brezinski and J. G. Fujimoto, "Optical coherence tomography: High-resolution imaging in nontransparent tissue," IEEE J. Select. Topics Quantum Electron., vol. 5, pp. 1185-1192, July-Aug. 1999.
10. J. A. Izatt, M. D. Kulkarni, H. W. Wang, K. Kobayashi, and M. V. Sivak, "Optical coherence tomography and microscopy in gastrointestinal tissues," IEEE J. Select. Topics Quantum Electron., vol. 2, pp. 1017-1028, Dec. 1996.
11. M. E. Zevallos, S. K. Gayen, B. B. Das, M. Alrubaiee, and R. R. Alfano, "Picosecond electronic time-gated imaging of bones in tissues," IEEE J. Select. Topics Quantum Electron., vol. 5, pp. 916-922, July-Aug. 1999.
12. K. Chen, L. T. Perelman, Q. Zhang, R. R. Dasari, and M. S. Feld, "Optical computed tomography in a turbid medium using early arriving photons," J. Biomed. Opt., vol. 5, pp. 144-154, 2000.
13. S. K. Gayen, M. Alrubaiee, H. E. Savage, S. P. Schantz, and R. R. Alfano, "Parotid gland tissues investigated by picosecond time-gated and optical spectroscopic imaging techniques," IEEE J. Select. Topics Quantum Electron., vol. 7, pp. 906-911, Nov.-Dec. 2001.
14. L. T. Perelman, V. Backman, M. Wallace, G. Zonios, R. Manoharan, A. Nusrat, S. Shields, M. Seiler, C. Lima, T. Hamano, I. Itzkan, J. Van Dam, J. M. Crawford, and M. S. Feld, "Observation of periodic fine structure in reflectance from biological tissue: a new technique for measuring nuclear size distribution," Phys. Rev. Lett., vol. 80, pp. 627-630, 1998.
15. A. H. Hielscher, J. R. Mourant, and I. J. Bigio, "Influence of particle size and concentration on the diffuse backscattering of polarized light from tissue phantoms and biological cell suspensions," Appl. Opt., vol. 37, pp. 125-135, 1997.
16. S. G. Demos, H. B. Radousky, and R. R. Alfano, "Deep subsurface imaging in tissues using spectral and polarization filtering," Opt. Exp., vol. 7, pp. 23-28, 2000.
17. S. G. Demos and R. R. Alfano, "Optical polarization imaging," Appl. Opt., vol. 36, pp. 150-155, 1997.
18. S. G. Demos, A. J. Papadopoulos, H. Savage, A. S. Heerdt, S. Schantz, and R. R. Alfano, "Polarization filter for biomedical tissue optical imaging," Photochem. Photobiol., vol. 66, pp. 821-825, 1997.
19. S. L. Jacques, J. R. Roman, and K. Lee, "Imaging superficial tissues with polarized light," Laser Surg. Med., vol. 26, pp. 119-129, 2000.
20. S. L. Jacques, J. C. Ramella-Roman, and K. Lee, "Imaging skin pathology with polarized light," J. Biomed. Opt., vol. 7, pp. 329-340, 2002.
21. V. Backman, R. Gurjar, K. Badizadegan, R. Dasari, I. Itzkan, L. T. Perelman, and M. S. Feld, "Polarized light scattering spectroscopy for quantitative measurement of epithelial cellular structures in situ," IEEE J. Select. Topics Quantum Electron., vol. 5, pp. 1019-1026, July-Aug. 1999.
22. V. Backman, L. T. Perelman, J. T. Arendt, R. Gurjar, M. G. Muller, Q. Zhang, G. Zonios, E. Kline, T. McGillican, T. Valdez, J. Van Dam, M. Wallace, K. Badizadegan, J. M. Crawford, M. Fitzmaurice, S. Kabani, H. S. Levin, M. Seiler, R. R. Dasari, I. Itzkan, and M. S. Feld, "Detection of preinvasive cancer cells in situ," Nature, vol. 406, pp. 35-36, 2000.
23. V. Backman, V. Gopal, M. Kalashnikov, K. Badizadegan, R. Gurjar, A. Wax, I. Georgakoudi, M. Mueller, C. W. Boone, R. R. Dasari and M. S. Feld, "Measuring cellular structure at submicron scale with light scattering spectroscopy," IEEE J. Select. Topics Quantum Electron., vol. 7, pp. 887-894, Nov.-Dec. 2001.
24. R. Gurjar, V. Backman, L. T. Perelman, I. Georgakoudi, K. Badizadegan, R. Dasari, I. Itzkan, and M. S. Feld, "Imaging of human epithelial properties with polarized light scattering spectroscopy," Nature Med., vol. 7, pp. 1245-1248, 2001.
25. J. R. Mourant, T. M. Johnson, S. Carpenter, A. Guerra, T. Aida, and J. P. Freyer, "Polarized angular dependent spectroscopy of epithelial cells and epithelial cell nuclei to determine the size scale of scattering structures," J. Biomed. Opt., vol. 7, pp. 378-387, 2002.
26. J. R. Mourant, J. P. Freyer, A. H. Hielscher, A. A. Eick, D. Shen, and T. M. Johnson, "Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics," Appl. Opt., vol. 37, pp. 3586-3593, 1998.
27. H. C. Van de Hulst, Light Scattering by Small Particles. New York: Dover, 1995.
28. R. G. Newton, Scattering Theory of Waves and Particles. New York: McGraw-Hill, 1969.
29. M. Kobaek-Larsen, I. Thorup, A. Diederichsen, C. Fenger, and M. R. Hoitinga, "Review of colorectal cancer and its metastases in rodent models: Comparative aspects with those in humans," Comput. Med., vol. 50, pp. 16-26, 2000.
30. L. Roncucci, M. Pedroni, F. Vaccina, P. Benatti, L. Marzona, and A. De Pol, "Aberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics," Cell Prolif., vol. 33, pp. 1-18, 2000.
31. D. C. Chung, "The genetic basis of colorectal cancer: insights into critical pathways of tumorigenesis," Gastroenterol., vol. 119, pp. 854-865, 2000.
32. R. K. Wali, S. Khare, M. Tretiakova, G. Cohen, L. Nguyen, J. Hart, J. Wang, M. Wen, L. Joseph, A. Ramaswamy, M. Sitrin, T. Brasitus and M. Bissonnette, "Ursodeoxycholic acid and F6-D3 inhibit aberrant crypt proliferation in the rat AOM model of colon cancer: roles of cyclin D1 and E-cadherin," Cancer Epidemiol. Biomarkers Prev., vol. 11, pp. 1653-1662, 2002.
33. J. Folkman, "Tumor angiogenesis," in The Molecular Basis of Cancer, J. Mendelsohn, P. M. Howley, M. A. Isreal, and L. A. Liotta, Eds. Philadelphia, PA: Saunder, 1995, pp. 206-232.
34. J. M. Schmitt and G. Kumar, "Optical scattering properties of soft tissue: a discrete particle model," Appl. Opt., vol. 37, pp. 2788-2797, 1998.
35. A. J. Einstain, H. S. Wu, and J. Gil, "Self-affinity and lacunarity of chromatin texture in benign and malignant breast epithelial cell nuclei," Phys. Rev. Lett., vol. 80, pp. 397-400, 1998.
36. J. W. Baish and R. K. Jain, "Fractals and cancer," Cancer Res., vol. 60, pp. 3683-3688, 2000.
37. J. Teixeira, "Experimental methods for studying fractal aggregates," in On Growth and Form Fractal and Non-Fractal Patterns in Physics, H. E. Stanley and N. Ostrowsky, Eds. Boston, MA: Martinus Nijhoff, 1986, pp. 145-162.
38. A. Wax, C. Yang, V. Backman, K. Badizadegan, C. W. Boone, R. R. Dasari, and M. S. Feld, "Cellular organization and substructure measured using single-resolved low-coherence interferometry," Biophys. J., vol. 82, pp. 2256-2264, 2002.
39. J. B. A. Card and A. R. Jones, "An investigation of the potential of polarized light scattering for the characterization of irregular particles," J. Phys. D: Appl. Phys., vol. 32, pp. 2467-2474, 1999.
40. I. Georgakoudi, V. Backman, E. Sheets, M. Muller, C. Crum, K. Badizadegan, M. Dasari, and M. S. Feld, "Diagnosis of cervical dysplasia with tri-modal spectroscopy," Amer. J. Obstet. Gynaecol., vol. 186, pp. 374-382, 2002.