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Volumn 47, Issue 11, 2003, Pages 883-894

TCRδ Gene Rearrangements Revealed by Fine Structure of the Recombination Junction in Mice

Author keywords

Nucleotide insertions; Replacement joints; TCR mutant; V D and D D rearrangements

Indexed keywords

T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN;

EID: 0242493025     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2003.tb03455.x     Document Type: Article
Times cited : (2)

References (35)
  • 2
    • 0029852090 scopus 로고    scopus 로고
    • Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity
    • Candeias, S., Muegge, K., and Durum, S.K. 1996. Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity. J. Exp. Med. 184: 1919-1926.
    • (1996) J. Exp. Med. , vol.184 , pp. 1919-1926
    • Candeias, S.1    Muegge, K.2    Durum, S.K.3
  • 3
    • 0027285604 scopus 로고
    • V(D)J recombination generates a high frequency of nonstandard TCR Dδ-associated rearrangements in thymocytes
    • Carroll, A.M., Slack, J.K., and Mu, X. 1993. V(D)J recombination generates a high frequency of nonstandard TCR Dδ-associated rearrangements in thymocytes. J. Immunol. 150: 2222-2230.
    • (1993) J. Immunol. , vol.150 , pp. 2222-2230
    • Carroll, A.M.1    Slack, J.K.2    Mu, X.3
  • 4
    • 0023198749 scopus 로고
    • A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation
    • Chien, Y., Iwashima, M., Kaplan, K.B., Elliott, J.F., and Davis, M.M. 1987. A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation. Nature 327: 677-682.
    • (1987) Nature , vol.327 , pp. 677-682
    • Chien, Y.1    Iwashima, M.2    Kaplan, K.B.3    Elliott, J.F.4    Davis, M.M.5
  • 6
    • 0018843979 scopus 로고
    • An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH
    • Early, P., Huang, H., Davis, M., Calame, K., and Hood, L. 1980. An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. Cell 19: 981-992.
    • (1980) Cell , vol.19 , pp. 981-992
    • Early, P.1    Huang, H.2    Davis, M.3    Calame, K.4    Hood, L.5
  • 7
    • 0023873953 scopus 로고
    • The adult T-cell receptor δ-chain is diverse and distinct from that of fetal thymocytes
    • Elliott, J.F., Lock, E.P., Patten, P.A., Davis, M.M., and Chien, Y. 1988. The adult T-cell receptor δ-chain is diverse and distinct from that of fetal thymocytes. Nature 331: 627-631.
    • (1988) Nature , vol.331 , pp. 627-631
    • Elliott, J.F.1    Lock, E.P.2    Patten, P.A.3    Davis, M.M.4    Chien, Y.5
  • 8
    • 0029065488 scopus 로고
    • Crucial role of the pre-T cell receptor α gene in the development of αβ but not γδ T cells
    • Fehling, H., Krotkova, A., Saint-Ruf, C., and von Boehmer, H. 1995. Crucial role of the pre-T cell receptor α gene in the development of αβ but not γδ T cells. Nature 375: 795-798.
    • (1995) Nature , vol.375 , pp. 795-798
    • Fehling, H.1    Krotkova, A.2    Saint-Ruf, C.3    Von Boehmer, H.4
  • 9
    • 0025137478 scopus 로고
    • On the mechanism of non-allelically excluded Vα-Jα T cell lymphoma
    • Fondell, J.D., Marolleau, J.P., Primi, D., and Marcu, K.B. 1990. On the mechanism of non-allelically excluded Vα-Jα T cell lymphoma. J. Immunol. 144: 1094-1103.
    • (1990) J. Immunol. , vol.144 , pp. 1094-1103
    • Fondell, J.D.1    Marolleau, J.P.2    Primi, D.3    Marcu, K.B.4
  • 10
    • 0023661686 scopus 로고
    • Isolation of an excision product of T-cell receptor α-chain gene rearrangements
    • Fujimoto, S., and Yamagishi, H. 1987. Isolation of an excision product of T-cell receptor α-chain gene rearrangements. Nature 327: 242-243.
    • (1987) Nature , vol.327 , pp. 242-243
    • Fujimoto, S.1    Yamagishi, H.2
  • 11
    • 0027452074 scopus 로고
    • Mice lacking TdT: Mature animals with an immature lymphocyte repertoire
    • Gifillan, S., Dierich, A., Lemeur, M., Benoist, C., and Mathis, D. 1993. Mice lacking TdT: mature animals with an immature lymphocyte repertoire. Science 261: 1175-1178.
    • (1993) Science , vol.261 , pp. 1175-1178
    • Gifillan, S.1    Dierich, A.2    Lemeur, M.3    Benoist, C.4    Mathis, D.5
  • 12
    • 0026016422 scopus 로고
    • Lack of feedback inhibition of Vκ gene rearrangement by productively rearranged alleles
    • Harada, K., and Yamagishi, H. 1991. Lack of feedback inhibition of Vκ gene rearrangement by productively rearranged alleles. J. Exp. Med. 173: 409-415.
    • (1991) J. Exp. Med. , vol.173 , pp. 409-415
    • Harada, K.1    Yamagishi, H.2
  • 13
    • 0029924217 scopus 로고    scopus 로고
    • Productive T-cell receptor β-chain gene rearrangement: Coincident regulation of cell cycle and clonality during development in vivo
    • Hoffman, E.S., Passoni, L., Crompton, T., Leu, T.M.J., Schatz, D.G., Koff, A., Owen, M.J., and Hayday, A.C. 1996. Productive T-cell receptor β-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo. Genes Dev. 10: 948-962.
    • (1996) Genes Dev. , vol.10 , pp. 948-962
    • Hoffman, E.S.1    Passoni, L.2    Crompton, T.3    Leu, T.M.J.4    Schatz, D.G.5    Koff, A.6    Owen, M.J.7    Hayday, A.C.8
  • 14
    • 0026548415 scopus 로고
    • Novel excision products of T cell receptor γ gene rearrangements and developmental stage specificity implied by the frequency of nucleotide insertions at signal joints
    • Iwasato, T., and Yamagishi, H. 1992. Novel excision products of T cell receptor γ gene rearrangements and developmental stage specificity implied by the frequency of nucleotide insertions at signal joints. Eur. J. Immunol. 22: 101-106.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 101-106
    • Iwasato, T.1    Yamagishi, H.2
  • 15
    • 0023760731 scopus 로고
    • Variable region (Vδ) gene segment most frequently utilized in adult thymocytes is 3′ of the constant (Cδ) region
    • Iwashima, M., Green, A., Davis, M.M., and Chien, Y. 1988. Variable region (Vδ) gene segment most frequently utilized in adult thymocytes is 3′ of the constant (Cδ) region. Proc. Natl. Acad. Sci. U.S.A. 85: 8161-8165.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 8161-8165
    • Iwashima, M.1    Green, A.2    Davis, M.M.3    Chien, Y.4
  • 17
    • 0032052230 scopus 로고    scopus 로고
    • Variable gene segment-specific N-insertions at the signal joint of T-cell receptor Vβ-Dβ recombinations
    • Kanari, Y., Nakagawa, R., Arakawa, H., and Yamagishi, H. 1998. Variable gene segment-specific N-insertions at the signal joint of T-cell receptor Vβ-Dβ recombinations. Immunol. Lett. 61: 151-155.
    • (1998) Immunol. Lett. , vol.61 , pp. 151-155
    • Kanari, Y.1    Nakagawa, R.2    Arakawa, H.3    Yamagishi, H.4
  • 18
    • 0027369562 scopus 로고
    • Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes
    • Komori, T., Okada, A., Stewart, V., and Alt, F.W. 1993. Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes. Science 261: 1171-1178.
    • (1993) Science , vol.261 , pp. 1171-1178
    • Komori, T.1    Okada, A.2    Stewart, V.3    Alt, F.W.4
  • 19
    • 0024532334 scopus 로고
    • Rearrangement by inversion of a T-cell receptor δ variable region gene located 3′ of the δ constant region gene
    • Korman, A.J., Maruyama, J., and Raulet, D.H. 1989. Rearrangement by inversion of a T-cell receptor δ variable region gene located 3′ of the δ constant region gene. Proc. Natl. Acad. Sci. U.S.A. 86: 267-271.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 267-271
    • Korman, A.J.1    Maruyama, J.2    Raulet, D.H.3
  • 20
    • 0022579722 scopus 로고
    • The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition
    • Kronenberg, M., Siu, G., Hood, L., and Shastri, N. 1986. The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition. Annu. Rev. Immunol. 4: 529-591.
    • (1986) Annu. Rev. Immunol. , vol.4 , pp. 529-591
    • Kronenberg, M.1    Siu, G.2    Hood, L.3    Shastri, N.4
  • 21
    • 0024791338 scopus 로고
    • Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining
    • Lafaille, J.J., DeCloux, A., Bonneville, M., Takagaki, Y., and Tonegawa, S. 1989. Junctional sequences of T cell receptor γδ genes: implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining. Cell 59: 859-870.
    • (1989) Cell , vol.59 , pp. 859-870
    • Lafaille, J.J.1    DeCloux, A.2    Bonneville, M.3    Takagaki, Y.4    Tonegawa, S.5
  • 22
    • 0028012025 scopus 로고
    • Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor δ transgene
    • Lauzurica, P., and Krangel, M.S. 1994. Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor δ transgene. J. Exp. Med. 179: 43-55.
    • (1994) J. Exp. Med. , vol.179 , pp. 43-55
    • Lauzurica, P.1    Krangel, M.S.2
  • 23
    • 0024255703 scopus 로고
    • Novel strand exchanges in V(D)J recombination
    • Lewis, S.M., Hesse, J.E., Mizuuchi, K., and Gellert, M. 1988. Novel strand exchanges in V(D)J recombination. Cell 55: 1099-1107.
    • (1988) Cell , vol.55 , pp. 1099-1107
    • Lewis, S.M.1    Hesse, J.E.2    Mizuuchi, K.3    Gellert, M.4
  • 24
    • 0004066515 scopus 로고
    • V(D)J recombination: Nucleotide insertion at signal joints as well as coding joints
    • Lieber, M.R., Hesse, J.E., Mizuuchi, K., and Gellert, M. 1988. V(D)J recombination: nucleotide insertion at signal joints as well as coding joints. Proc. Natl. Acad. Sci. U.S.A. 85: 8588-8592.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 8588-8592
    • Lieber, M.R.1    Hesse, J.E.2    Mizuuchi, K.3    Gellert, M.4
  • 25
    • 0024294021 scopus 로고
    • The joining of germ-line Vα to Jα genes replaces the preexisting Vα-Jα complexes in a T cell receptor α, β positive T cell line
    • Marolleau, J.P., Fondell, J.D., Malissen, M., Trucy, J., Barbier, E., Marcu, K.B., Cazenave, P.A., and Primi, D. 1988. The joining of germ-line Vα to Jα genes replaces the preexisting Vα-Jα complexes in a T cell receptor α, β positive T cell line. Cell 55: 291-300.
    • (1988) Cell , vol.55 , pp. 291-300
    • Marolleau, J.P.1    Fondell, J.D.2    Malissen, M.3    Trucy, J.4    Barbier, E.5    Marcu, K.B.6    Cazenave, P.A.7    Primi, D.8
  • 28
    • 0024024315 scopus 로고
    • Thymocyte circular DNA excised from T cell receptor α-δ gene complex
    • Okazaki, K., and Sakano, H. 1988. Thymocyte circular DNA excised from T cell receptor α-δ gene complex. EMBO J. 7: 1669-1674.
    • (1988) EMBO J. , vol.7 , pp. 1669-1674
    • Okazaki, K.1    Sakano, H.2
  • 29
    • 0030753633 scopus 로고    scopus 로고
    • Cell-free V(D)J recombination
    • Ramsden, D.A., Paull, T.T., and Gellert, M. 1997. Cell-free V(D)J recombination. Nature 388: 488-491.
    • (1997) Nature , vol.388 , pp. 488-491
    • Ramsden, D.A.1    Paull, T.T.2    Gellert, M.3
  • 30
    • 0019214271 scopus 로고
    • Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes
    • Sakano, H., Maki, R., Kurosawa, Y., Roeder, W., and Tonegawa, S. 1980. Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes. Nature 286: 676-683.
    • (1980) Nature , vol.286 , pp. 676-683
    • Sakano, H.1    Maki, R.2    Kurosawa, Y.3    Roeder, W.4    Tonegawa, S.5
  • 31
    • 0027092286 scopus 로고
    • Biased reading frames of pre-existing DH-JH coding joints and preferential nucleotide insertions at VH-DJH signal joints of excision products of immunoglobulin heavy chain gene rearrangements
    • Shimizu, T., and Yamagishi, H. 1992. Biased reading frames of pre-existing DH-JH coding joints and preferential nucleotide insertions at VH-DJH signal joints of excision products of immunoglobulin heavy chain gene rearrangements. EMBO J. 11: 4869-4875.
    • (1992) EMBO J. , vol.11 , pp. 4869-4875
    • Shimizu, T.1    Yamagishi, H.2
  • 32
    • 0024433735 scopus 로고
    • Excision products of the T cell receptor gene support a progressive rearrangement model of the α/δ locus
    • Takeshita, S., Toda, M., and Yamagishi, H. 1989. Excision products of the T cell receptor gene support a progressive rearrangement model of the α/δ locus. EMBO J. 8: 3261-3270.
    • (1989) EMBO J. , vol.8 , pp. 3261-3270
    • Takeshita, S.1    Toda, M.2    Yamagishi, H.3
  • 33
    • 0023711742 scopus 로고
    • Structure of extrachromosomal circular DNAs excised from T-cell antigen receptor alpha and delta-chain loci
    • Toda, M., Fujimoto, S., Iwasato, T., Takeshita, S., Tezuka, K., Ohbayashi, T., and Yamagishi, H. 1988. Structure of extrachromosomal circular DNAs excised from T-cell antigen receptor alpha and delta-chain loci. J. Mol. Biol. 202: 219-231.
    • (1988) J. Mol. Biol. , vol.202 , pp. 219-231
    • Toda, M.1    Fujimoto, S.2    Iwasato, T.3    Takeshita, S.4    Tezuka, K.5    Ohbayashi, T.6    Yamagishi, H.7
  • 34
    • 0030963615 scopus 로고    scopus 로고
    • Structure and function of the pre-T cell receptor
    • Von Boehmer, H., and Fehling, H.L. 1997. Structure and function of the pre-T cell receptor. Annu. Rev. Immunol. 15: 433-452.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 433-452
    • Von Boehmer, H.1    Fehling, H.L.2
  • 35
    • 0024598827 scopus 로고
    • Separate lineages of T cells expressing the αβ and γδ receptors
    • Winoto, A., and Baltimore, D. 1989. Separate lineages of T cells expressing the αβ and γδ receptors. Nature 338: 430-432.
    • (1989) Nature , vol.338 , pp. 430-432
    • Winoto, A.1    Baltimore, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.